12-9 and 12-10
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Turn In: Concept Map and Vocabs
Warm up# 11-15
Notes: Cell Differentiation
Quiz Cell Cycle
Drawing 2-D Model Activity
HF: None  Just study your semester exam
Cell Differentiation
Defining Differentiation
During the development of an organism, cells differentiate to
specialized
become
.
Store sugar
Carry out
photosynthesis
Transport
materials
What Are Stem Cells?
unspecialized
Stem cells are the
differentiated cells develop.
Totipotent: “can do everything”
Pluripotent: “can do most things”
cells from which
Embryonic Stem Cells
embryonic
stem cells
Adult Stem Cells
• Multipotent: “can do many things”
• Give rise to limited number of cell
types
• Mainly found in bone marrow, hair
follicles
• Also some in brain, heart, and
skeletal muscle
Regenerative Medicine
Undifferentiated cells are used to repair or replace
damaged cells and tissues.
STEM CELLS
Unspecialized cells that have the
potential to differentiate (to
become any type of cell)
Stem cells can be found in:
Human embryos
Some adult cells
Cord blood
The use of embryonic stem cells is
controversial. Why?
Potential Uses for Stem Cells
Repair injuries of the brain and spinal cord
Cure some diseases (diabetes)
Replace organs (liver tissue, heart valves)
Ethical Issues
•Human adult stem cell research is
rarely controversial because of willing
donors.
• Human embryonic stem cell
research is controversial because
arguments for and against involve
ethical issues of life and death.
Cellular Reprogramming
• Induced Pluripotent Stem
Cells (iPS)
• May ultimately help society
reframe the debate over use
of stem cells
Dr. Shinya Yamanaka