Chapter 7 The Vitamins Nutrition: Concepts & Controversies, 12e Sizer/Whitney Definition and Classification of Vitamins Vitamin Essential, noncaloric, organic Role of vitamins Vitamin precursors Classes Absorption Roles Vitamin Names Characteristics of the Fat-Soluble and Water-Soluble Vitamins The Fat-Soluble Vitamins A, D, E, and K Food sources Storage Toxicity Deficiency Roles within the body Vitamin A Precursor Beta-carotene Active forms in the body Retinol Retinal Retinoic acid Food sources Vitamin A Deficiency and Toxicity Vitamin A – Snapshot Beta-Carotene Plant-based foods Colorful groups Macular degeneration Dietary antioxidant Measuring beta-carotene Retinol activity equivalents (RAE) Toxicity Food sources Vitamin D Body can synthesize all it needs Sunlight Transformation Liver and kidneys Estimated deficiency prevalence Vitamin D Ultraviolet B light rays Cholesterol Sunbathing risks Sunscreen Exposure times Intake recommendations Food sources Factors Affecting Vitamin D Synthesis Vitamin D - Snapshot Vitamin E Roles of vitamin E Antioxidant Deficiency Symptoms Toxicity Dietary intake vs. supplemental intake Recommendations Food source Free-Radical Damage and Antioxidant Protection Vitamin E – Snapshot Vitamin K – Snapshot The Water-Soluble Vitamins Dissolve in water Absorption Transport Excretion Sources Food Supplements Vitamin C Roles Connective tissues Collagen Antioxidant Protects iron Prooxidant Deficiency symptoms Scurvy Vitamin C – Snapshot The B Vitamins in Unison Function as part of coenzymes Combines with enzyme to activate it Coenzyme shape Roles in metabolism Help the body use the energy-yielding nutrients for energy Cell multiplication Coenzyme Action Some Roles of the B Vitamins in Metabolism: Examples Thiamin Energy metabolism of all cells Nerve cell membranes Deficiency Beriberi Alcohol abuse DRI recommendation Food sources Thiamin Snapshot Riboflavin Role in energy metabolism of all cells Deficiencies Examples Destruction of vitamin UV light Irradiation Heat Riboflavin Snapshot Niacin Participates in energy metabolism Deficiency Pellagra Toxicity Physician administration “Niacin flush” Niacin Snapshot Folate Helps synthesize DNA Normal metabolism of several amino acids Deficiency Causes Outcomes of deficiency Anemia, diminished Immunity, abnormal digestive function Cancer risk Interaction with medications Folate Snapshot Vitamin B12 Closely related to folate Helps maintain sheaths around nerve fibers Deficiency May be masked by folic acid intake Pernicious anemia Vitamin B12 absorption Intrinsic factor Food sources Vitamin B12 Snapshot Vitamin B6 Snapshot Some Valid Reasons for Taking Supplements Arguments Against Taking Supplements Food rarely causes nutrient imbalances or toxicities Toxicity Supplement contamination Lift-threatening misinformation Unknown needs False sense of security Whole foods are best