Mitosis and the Cell Cycle

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Bell Ringer (5)
What are the stages
of the cell cycle?
Bell Ringer
Put these
pictures of
mitosis in the
correct order.
Sketch them.
Label each
phase.
Mitosis Foldable
Materials: 3 pieces of white paper
Stagger the pages about 1 inch apart.
Fold the pages “hamburger style” to make
6 flaps.
Label the flaps as follows: (1) The Cell
Cycle & Mitosis (2) Interphase (3)
Prophase (4) Metaphase (5) Anaphase (6)
Telophase & Cytokinesis
On the back, draw the cell cycle.
G1 phase
M phase
S phase
G2 phase
The Cell Cycle
Interphase (period in-between division)
– G1 (growth)
– S (DNA replication)
– G2 (prepare for mitosis)
M phase (division)
– Mitosis (division of the nucleus)
– Cytokinesis (division of the cytoplasm)
Most of the time the cell is in interphase!!!
Interphase
1. G1 (growth)
2. S (DNA replication)
3. G2 (prepare for mitosis)
Mitosis & Cytokinesis!
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Mitosis Facts
mitotic
cell
division
mitotic
cell
division
(a)
(b)
(c)
Multicellular organisms grow, maintain and
repair cells by mitosis.
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Replication
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DNA
Doubles
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Mitosis
Mitosis is the division of the
nucleus.
There are 4 stages of mitosis:
–Prophase
–Metaphase
–Anaphase
–Telophase
Terms
Centriole
 Centromere
 Spindle
 Chromosome
(sister
chromatids)

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Prophase
In this stage everything sets up for
mitosis. It is the first and longest stage
of mitosis.
The nucleolus disappears.
The chromatin condenses into
chromosomes.
The centrioles separate and form a
spindle of microtubules.
The nuclear membrane breaks down.
Prophase
centromeres
sister chromatids
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Metaphase
Metaphase is the 2nd phase of
mitosis.
The spindle attaches to the
centromere of the chromosomes.
The chromosomes line up on the
spindle in the MIDDLE of the cell.
Metaphase may last only a few
minutes.
Metaphase
Anaphase
Anaphase is the 3rd phase of mitosis.
In this phase the chromosomes are
pulled APART at the centromere.
Sister chromatids are pulled to
opposite ends of the cell.
Anaphase begins as soon as the
chromosomes begin separating and
ends as soon as the chromosomes
stop moving.
Anaphase
Telophase
This is the last phase of mitosis.
Chromosomes disperse and tangle
back into chromatin.
2 nuclear envelopes form around the
chromatin.
The spindle breaks down.
The nucleolus becomes visible.
Telophase
Cytokinesis
Cytokinesis is the division of the
cytoplasm.
It usually occurs at the same time
as telophase.
The cytoplasm can be divided 2
ways:
– Animal cells pinch off into 2 cells.
– Plant cells form a cell plate (which
is the beginning of the cell wall)
Cytokinesis
in
Animal
Cells
Cytokinesis
in
Plant Cells
Final Product
The final product of mitosis
and cytokinesis is:
–2 genetically identical
daughter cells
Mitosis - can you
name the stages?
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