Cell Division—Mitosis Notes Cell Division — process by which a cell divides into __________ • Why do cells need to divide? 1.Living things _______ by producing _________, NOT because each cell increases in size 2._________ of damaged tissue 3.If cell gets too big, it _______ get enough _________ into the cell and _______ out of the cell • The _________ cell is called the _________ cell; 2 ______ cells are called ___________ cells • Before cell division occurs , the cell _________ (copies) all of its ______, so each daughter cell gets complete set of _______________ from parent cell • Each daughter cell is ___________ like the parent cell – _________ kind and number of _______________ as the original cell 2 Daughter Cells Parent Cell •Many organisms, especially ____________organisms, reproduce by means of cell division – called ___________________ – Ex: bacteria DNA • DNA is located in the ____________and controls all cell _____________ including cell division • Long and ____________ DNA in a ______________ cell is called _______________ • ____________, ___________, short DNA in a _______________cell is called _________________ Consists of 2 parts: ____________ and ______________ o 2 identical “sister” chromatids attached at an area in the middle called a ____________ o When cells divide, “sister” ________________ separate and 1 goes to each new cell •Chromatin to chromosomes illustration: Chromatin Duplicates itself Why does DNA need to change from chromatin to chromosome? Coils up into chromosomes More _________division Chromosome number • Every organism has its own ___________________ of chromosomes Examples: Human = ____ chromosomes or ________ Dog = ____ chromosomes or ___________ Goldfish = ____ chromosomes or _______ Lettuce = _____ chromosomes or _______ • All ____________ (body) cells in an organism have the __________ kind and ____________ of chromosomes Examples: Human = _______ chromosomes Human skin cell = _____ chromosomes Human heart cell = _____ chromosomes Human muscle cell = ____ chromosomes Fruit fly = ______chromosomes Fruit fly skin cell = ___ chromosomes Fruit fly heart cell = ___chromosomes Fruit fly muscle cell =__chromosomes Cell Cycle -- series of events cells go through as they _______ and __________ •Cell ________, prepares for division, then _________ to form 2 ____________cells – each of which then begins the cycle again Interphase—period of cell _______ and ___________ •DNA __________ (copying) occurs during Interphase •During Interphase the cell also ________, carries out normal __________, replicates all other ___________ •The cell spends most of its life cycle in _____________ Mitosis – division of the _________ into 2 nuclei, each with the same number of _______________ •Mitosis occurs in _____ the _________ (body) cells So ____ new ____________ Why does mitosis occur? cell has ___________ with a complete set of _____________ • 4 phases of nuclear division (mitosis), directed by the cell’s DNA (___________) _________ _________—(Middle) Anaphase—(Apart) _____________—(Apart) __________—(Two) __________ Chromosomes _______ ____ Nuclear envelope ____________ _________ ______ form ______________—(Middle) Chromosomes line up in __________ of cell Spindle fibers _____________ to chromosomes _____________—(Apart) Chromosome copies __________ Spindle fibers pull chromosomes to _______________ ______________— (Two) Chromosomes ____________ Nuclear envelopes __________ __________________ are formed Spindle fibers ________________ Cytokinesis — the ____________ of the rest of the cell (_______________ and organelles) after the nucleus divides In _____________ cells the cytoplasm pinches in In _________ cells a cell plate forms •After mitosis and cytokinesis, the cell returns to ________________to continue to grow and perform regular cell activities Summary: Cell Cycle Interphase Mitosis (PMAT) Cytokinesis •When cells become old or damaged, they ______ and are replaced with __________ cells Cell Division Control •_______ controls _____cell activities including cell ______________ •Some cells _________ their ability to _________ their rate of cell division – the DNA of these cells has become ___________ or changed (mutated) •These super-dividing cells form masses called ____________ •_________ tumors are _____ cancerous – these cells do not spread to other parts of the body •_________ tumors are ___________ – these cells break loose and can invade and _____________ in other parts of the body (called metastasis) •Cancer is not just one disease, but ______ diseases – over _____ different types of cancers http://www.youtube.com/watch?v=wRrNjHYxP_o http://www.bbc.co.uk/blogs/adamcurtis/2010/06/th e_undead_henrietta_lacks_and.html Phase Chromosome Appearance & Location Important Events Interphase DNA copies itself; chromatin DNA replication, cell grows and replicates organelles Chromosomes coil up Nuclear envelope disappears, spindle fibers form Chromosomes line up in the middle Spindle fibers connect to chromosomes Anaphase Chromosome copies divide and move apart Telophase Chromosomes uncoil back into chromatin Cytokinesis Chromatin Spindle fibers pull chromosome copies apart to opposite poles Nuclear envelopes reform, 2 new nuclei are formed, spindle fibers disappear Division of the rest of the cell: cytoplasm and organelles Prophase Metaphase