1749-1823
British
Vaccine for smallpox created from cowpox
"Vaccination," the word
Jenner invented for his treatment (from the Latin vacca , a cow), was adopted by Pasteur for immunization against any disease.
“Father of Microbiology”
1822-1895
He solved the mysteries of rabies, anthrax, chicken cholera, and silkworm diseases, and contributed to the development of the first vaccines.
“Founder of Microbiology”
German
The Nobel Prize in
Physiology of
Medicine 1905
Koch formulated systematic method for biological research
( Koch's Postulates)
Pathogen must be found in infected organism.
Pathogen must be isolated & grown in lab
Pathogen grown in lab & introduced to healthy organism must cause the same disease
Injected pathogen must be isolated from the second host
Biologist/Pharmacologist
Scottish
In 1914, he joined British Royal
Army Medical Corps to develop a cure to reduce the number of soldiers dying from infected wounds.
Discovered penicillin in
1928
1930’s other scientists discovered a way to mass produce penicillin
Microorganisms that are harmless or beneficial to other organisms
–
Examples
•
Yeast & bacteria in mouth & throat
•
Bacteria in large intestine
Zoonosis = any disease that can be transmitted from animals to humans.
–
Ex. West Nile, Lyme Disease, Ebola
Vector = transport disease from animal to human
- usually do not get sick themselves ex. Deer Tick is vector for Lyme Disease
http://www.reformation.org/pasteur.html
http://nobelprize.org/nobel_prizes/medicine/laureates/1905/kochbio.htmlhttp://search.nobelprize.org/search/nobel/?q=Alexander+Flemi ng&i=en
http://nobelprize.org/educational_games/medicine/immunity/game/ind ex.html
Game above http://www.sjsu.edu/depts/Museum/flemin.html
http://www.accessexcellence.org/RC/AB/BC/Louis_Pasteur.html
http://www.sc.edu/library/spcoll/nathist/jenner.html
http://web.ukonline.co.uk/b.gardner/Koch.htm