http://www.mennellmedia.co.uk/Biology%20-%20Organisms.html •HOW LONG ARE YOUR INTESTINES? At least 25 feet in an adult. Be glad you're not a full-grown horse -- their coiled-up intestines are 89 feet long! •Chewing food takes from 5-30 seconds •Swallowing takes about 10 seconds •Food sloshing in the stomach can last 3-4 hours •It takes 3 hours for food to move through the intestine •Food drying up and hanging out in the large intestine can last 18 hours to 2 days! •Americans eat about 700 million pounds of peanut butter. •Americans eat over 2 billion pounds of chocolate a year. •In your lifetime, your digestive system may handle about 50 tons!! 2 Main Groups I. Alimentary : digests food, breaks it down into smaller fragments and absorbs the digested fragments through its lining into the blood II. Accessory Digestive Organs : assist the process of digestion I. Alimentary Canal *Also called gastrointestinal (GI) tract, and is technically considered to be outside the body b/c it is in contact with the external environment at both ends. Includes the following organs: -mouth -pharynx -esophagus -stomach -sm intestine -lg intestine -anus *Approx 30 feet in a cadaver but smaller in a living person b/c of its constant muscle tone. I. Alimentary Canal 4 Distinct Tissue Layers p741 Fig 25-2 1. Mucosa – innermost layer that lines the cavity or lumen. It secretes mucus and digestive enzymes. In some areas it has folds and tiny projections that help inc the surface area for absorption. 2. Submucosa – beneath the mucosa, contains blood vessels, nerve endings and lymphatic vessels. It nourishes and carries away absorbed material. 3. Muscular layer - a muscle layer made up of circular inner layer and a longitudinal outer layer of smooth muscle cells. I. Alimentary Canal 4. Serous layer - (serosa) outer covering of the tube, composed of visceral peritoneum. Its cells secrete serous fluid to keep the tube’s outer surface lubricated and moist so organs can slide freely against one another. I. Alimentary Canal Mixing and Propelling Movements Mixing - muscular contractions along its walls from end to end mix digestive juices secreted by the mucosa. Propelling - wavelike motion called peristalsis pushes tubular contents ahead. Lips – protect anterior opening A. Mouth Cheeks – protect lateral walls Hard palate – anterior roof Soft palate – posterior roof Uvula – finger-like projection of the soft palate Palantine tonsils – back of mouth on either side of tongue P747 Fig 25-8 Primary teeth & Secondary teeth Tongue – muscular structure A. Mouth Food enters mouth and is chewed and mixed with saliva (bolus). Cheeks and lips hold food between teeth during chewing. The tongue mixes food w/ saliva during chewing and initiates swallowing. Salivary gland – secrete saliva to help bind, moisten, and digest food. 2 Types of Secretory Cells 1. Serous cells – watery fluid that contains amylase 2. Mucous cells – thick, stringy liquid which helps bind food particles together and acts as a lubricant during swallowing. A. Mouth 3 Major Salivary Glands 1. Parotoid gland – largest, secretes a watery fluid rich in amylase 2. Submandibular gland – mostly serous cells and some mucous cells 3. Sublingual gland – floor of mouth under tongue, mostly mucous cells B. Pharynx •A passageway that connects the nasal and oral cavities with the larynx and esophagus 1. Nasopharynx – part of the respiratory passageway 2. Oropharynx – posterior to oral cavity where food moves from the mouth and air to and from the nasal cavity 3. Laryngopharynx – continuous with the esophagus P689 Fig 23-6 C. Esophagus p748 Fig 25-9 Esophagus – runs from pharynx through diaphragm to the stomach (approx 10 in long). Contains mucosa glands to keep inner lining moist and lubricated. Epiglottis - keeps food out of the air tube http://video.about.com/heartburn/HiatalHernia.htm GERD, and Hiatal Hernia http://www.bidmc.org/YourHealth/Proced uresInMotion.aspx D. Stomach Stomach - J-shaped or C-shaped pouchlike organ just under the liver and diaphragm in the upper left side of the abdominal cavity. *approx 10 inches long, when full can hold up to 1 gallon of food. *inner lining marked by folds or rugae *starts digestion of proteins, mixes food with gastric juices D. Stomach 1. 2. 3. 4. Divided into 4 Regions Cardiac - where food enters stomach from esophagus Fundic - expanded part of stomach, acts as temporary storage Body - midportion of stomach Pyloric - terminal part of stomach continuous with the small intestine P749 Fig 25-10 D. Stomach p749 Fig25-11 4 Different types of cells make up the gastric glands 1. Mucous cells - secrete mucus that protects and coats the inside stomach wall 2. Chief cells - secrete digestive enzymes….pepsin….protein splitting enzyme 3. Parietal cells - release HCl, makes stomach acidic and helps activate enzymes. 4. Endocrine cells - secretes the hormone gastrin that functions in increasing the gastric activity. The Hormones That Control Digestion 1. Gastrin - stimulates the stomach cells to inc the sections of the gastric glands. (gastric juice ….HCl & Pepsin) 2. Secretin - stimulates the release of pancreatic juice 3. Cholecystokinin (CCK) - stimulates the gallbladder to empty due to the presence of fat in the sm intestine. D. Stomach * In the pyloric region of the stomach where most digestive activity occurs you will find chyme - digested food mixed with gastric juices. The chyme leaves to the small intestine via the pyloric sphincter. Pyloric sphincter - a valve at end of pyloric canal that prevents food from reentering the stomach. E. Small Intestine Convoluted tube that extends from the pyloric sphincter to the ileocecal valve… where the ileum joins the cecum of the large intestine E. Small Intestine Mesentery - supporting tissues that contains blood vessels, nerves, and lymphatic vessels that supply the intestinal wall. *this fan-shaped mesentary holds the intestines together E. Small Intestine P752 Fig 25-13 Intestinal villi - tiny projections that come in contact with the intestinal contents and inc surface area for absorption. *nutrients are absorbed through the capillaries E. Small Intestine 1. Duodenum - curves around the head of the pancreas. The first part of the small intestine. 2. Jejunum - extends from the duodenum to the ileum 3. Ileum - terminal part of the small intestine. Joins lg intestine at ileocecal valve. Longest portion of the sm intestine E. Small Intestine Small Intestine Secretions * peptidase - split peptides into amino acids * sucrase, maltase, lactase - split double sugars * intestinal lipase - split fats F. Large Intestine *larger diameter than sm intestine and begins in the lower right side of the abdominal cavity where the ileum joins the cecum. *functions in drying out indigestible food residue by absorbing water so it can be eliminated from the body as feces. F. Large Intestine P754 Fig 25-16 *It frames the sm intestine on 3 sides and has the following subdivisions. 1. Appendix - hangs from the cecum and has no digestive function 2. Cecum - a pouch like structure at the beginning of the lg intestine. 3. Colon – Ascending: travels up right side Transverse: turns left to travel across the abdominal cavity Descending: travels down the left side Sigmoid: at pelvis where it make a S-shape F. Large Intestine P755 Fig 25-17 – 25-18 4. Rectum : just posterior to anal canal in the pelvis 5. Anal Canal : contains the anus which has an external voluntary sphincter and an internal involuntary sphincter. F. Large Intestine *Large intestine doesn’t have villi but has goblet cells to produce mucus. The mucus helps lubricate and prevent the intestine from the abrasiveness of the feces as it passes through. It also helps hold fecal matter together. http://www.bidmc.org/YourHealth/ProceduresInMotion.aspx II. Accessory Digestive Organs A. Pancreas *A soft pink, triangular gland that extends across the abdomen from the spleen to the duodenum. *It secretes enzymes into the duodenum to neutralize the acidic chyme. The pancreas also functions in producing the hormones insulin and glucagon. *secretin – hormone that stimulates pancreatic secretions B. Liver P757 Fig 25-22 *Largest gland in the body. Located under the diaphragm more to the right side of the body. Divided into lobes. Functions in: *Carbohydrate, lipid and protein metabolism *Storage of iron and vitamins *Blood filtering *Detoxification *Secretion of bile. B. Liver *Its digestive function is to provide bile. -Bile is made up of salts and is pigmented b/c of red blood cell breakdown. -Bile salts emulsify fat B. Liver -Bile leaves the liver through the hepatic duct and enters the duodenum through the common bile duct. C. Gallbladder -A small, green sac embedded in the inferior surface of the liver. *When digestion is not taking place the bile backs up the cystic duct and enters the gallbladder to be stored. *When fat is consumed a hormone (CCK) stimulates the gallbladder to release bile. C. Gallbladder P759-760 Fig 25-25 – 25-26 *Gallstones – when bile is stored in the gallbladder too long it crystallizes. The gallstones then prevent bile from entering the sm intestine and it eventually backs up into the liver and blood stream. http://www.innerbody.com/image/digeov.html http://www.medtropolis.com/VBody.asp