Cell Division Web Activity Name Period Date In this internet lesson, you will review the steps of mitosis and meiosis. You can either type out the sites listed or go to my web site and click on “My Resources” to click on the titles in the gray boxes. If any websites do not work at school, try them from home and notify the teacher if they still don’t work. Mitosis Tutorial http://www.cellsalive.com/ On the left side of the screen is a navigation bar, click on the link to “MITOSIS” Read the text on this page and view the animation, you can slow down the video by clicking step by step through the phases. 1. Which stage does the following occur: Chromatin condenses into chromosomes Chromosomes align in center of cell. Longest part of the cell cycle. Nuclear envelope breaks down. Cell is cleaved into two new daughter cells. Daughter chromosomes arrive at the poles. 2. Watch the video carefully. The colored chromosomes represent chromatids. There are two of each color because one is an exact duplicate of the other. --How many chromosomes are visible at the beginning of mitosis? --How many are in each daughter cell at the end of mitosis? --What are the green oval shaped structures in this video called? 3. Identify the stages of these cells: Mitosis Animation Go to www.johnkyrk.com/mitosis.html View the animation and sketch the cell in each phase in the top box. You will want to draw each cell near the end of that phase in the animation. In the bottom box, describe what is happening (if you hold the cursor over the phase, it tells you at the top). Prophase Metaphase Anaphase Telophase 1 Onion Root Tip Online Activity http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/cell_cycle.html or go to my web page and click “My Resources” and “Onion Root Activity” Read the introduction, then click the “next” button. Draw the onion root tips in each of their phases: Prophase Metaphase Anaphase Telophase Click Next. Click it again. Now, you will have 36 onion cells to classify. You do NOT have to record it as you do it, at the end you will get a summary table where you can count each phase. When you’re finished, record your data in the chart below. Interphase Number of cells Prophase Metaphase Anaphase Telophase Total 36 Cancer & Mitosis - Online Activity Go to www.insidecancer.org and click on Hallmarks of Cancer. Then click on overview. This talks about what cancer is and how it occurs. Read each slide and then answer the questions/fill in the blank. After you are done with the slide, click on the right arrow at the bottom of your screen. Slide 1- Cancer is a disease that________________________________________________________________________ Slide 2- There are many different types of cancers affecting different parts of the body. A cancer, or ____________, can occur _______________________________________. Solid tumors form ______________, while liquid tumors ________ __________________________. Slide 3- All cancers start with ________________________. The mutations are in the cell's _________________________ ________________________. Less than 10% of all cancer mutations are inherited. Usually, the mutation arises as a result __________________________________________. Slide 4- The DNA mutation may be a single _______________________ as shown below or a _________________ or ________________ of DNA sequence. A change in the genetic sequence can then lead to _________________________ __________________________________. Slide 5- Although in rare cases one mutation is enough, it is usually an _________________________________________ ________ a normal cell into a cancerous one. As we age, ________________________________________________; this explains why cancer incidence increases with age. Slide 6- These mutations can disrupt the _________________________________________________________________. This leads to the accumulation of more “rogue” cancer cells and the ___________________________________________. 2 **Click on Causes and Prevention. After you are done with the slide, click on the right arrow at the bottom of your screen. Slide 1- Despite the attention given to inherited cancer genes in the press, less than Slide 2- Many other people would like to blame cancer on and industrial wastes account for – but pollution, food additives, of cancers in the U.S. So what is really behind cancer? Slide 3- A world map can give surprising clues about cancer causes, as well as prevention. Although cancer affects people of all nationalities, epidemiologists look for cancer “hot spots” – , . Then they attempt to find , cultural, or lifestyle factors that are common to the regions where cancers are most frequent. **Click on the Examine the Worldwide Distribution of cancer types arrow. Click on the various types of cancers at the bottom to answer the following questions: 1. What type of cancer has 90.1-100 cases in 100,000 people in the US? 2. What do the hot spots for the cancer written above have in common? 3. How many cases per 100,000 are there in the US for lung cancer? 4. What do hotspots for lung cancer have in common? 5. Lung cancer is the leading cause of cancer deaths in the United States, but deaths would drop 85% if no one . Lew-Port's Meiosis Page- Go to http://www.lewport.com/10712041113402793/lib/10712041113402793/animations/meiosis.html to answer the following: 1. How many chromosomes does the cell in this animation start with? 2. The homologous pairs are represented by similar 3. Copies of chromosomes are held together by the 4. Each chromosome finds its . In each pair 5. Draw "crossing over" - using colored pencil to shade in the areas that exchange parts. 6. How many chromosomes are at each pole of the cell? 7. During meiosis 2, chromosomes line up again along the cell's 8. Only copy of each chromosome moves toward the poles. Which means only chromosomes of the original six. 9. New membranes form around each cells. Each cell divides, forming a total of 3 PBS: Mitosis vs. Meiosis - http://www.pbs.org/wgbh/nova/baby/ . Click on “How Cells Divide” then click “Mitosis VS Meiosis” In the chart below, SUMMARIZE what happens during the following by watching the animation AND reading the information Step Mitosis Meiosis Before We Split Interphase (I) Prophase and Prometaphase (I) Metaphase (I) Anaphase (I) Telophase (I) Cytokinesis Interphase (II) Prophase and Prometaphase (II) Metaphase (II) Anaphase (II) Telophase (II) Cytokinesis 4