1 2 Cell Cycle… • Does your cell cycle look something like this? 3 4 Lesson #1.3a - Mitosis 5 Identical Daughter Cells Two identical daughter cells Parent Cell 6 Chromosomes 7 Chromosomes in Dividing Cells Duplicated chromosomes are called sister chromatids & are held together by the centromere Called Sister Chromatids 8 Karyotype A picture of the chromosomes from a human cell arranged in pairs by size First 22 pairs are called autosomes Last pair are the sex chromosomes XX female or XY male 9 Boy or Girl? The Y Chromosome Decides Y - Chromosome X - Chromosome 10 Cell Reproduction 11 Types of Cell Reproduction Asexual reproduction involves a single cell dividing to make 2 new, identical cells, these are called daughter cells Mitosis & binary fission are examples of asexual reproduction Sexual reproduction involves two cells (egg & sperm) joining to make a new cell (zygote) that is NOT identical to the original cells Meiosis is an example 12 Cell Cycle DNA Copied Cells Mature Daughter Cells Cells prepare for Division Cell Divides into Identical cells 13 What’s Happening in Interphase? What the cell looks like Animal Cell What’s occurring 14 Mitosis 15 Mitosis Division of the nucleus Only occurs in eukaryotes Produces somatic cells (ALL but sex cells) Has four stages Doesn’t occur in some cells such as brain cells 16 Four Mitotic Stages Prophase Metaphase Anaphase Telophase 17 Early Prophase Chromatin in nucleus continues condensing Mitotic spindle forms from centrioles Microtubules make up the spindle fibres Nucleolus Cytoplasm Nuclear Membrane Chromosomes 18 Late Prophase Nuclear membrane & nucleolus are broken down Chromosomes continue condensing & are clearly visible Spindle fibers attach to the centromere of each chromosome Spindle begin to move to the opposite ends of the cell, stretching out the cell 19 Late Prophase Chromosomes Nucleus & Nucleolus have disintegrated 20 Review of Prophase What the cell looks like Centromeres What’s happening 21 Metaphase Chromosomes, attached to the centromeres and move to the center of the cell Chromosomes are now lined up in the middle 22 Metaphase Spindle Fibers Chromosomes lined up in the middle 23 Metaphase Chromosomes 24 Review of Metaphase What the cell looks like 25 Anaphase Occurs rapidly Sister chromatids are pulled apart to opposite poles of the cell by spindle fibers Cell elongates (gets wider) 26 Anaphase Sister Chromatids being separated 27 Anaphase Review What the cell looks like What’s occurring 28 Telophase Sister chromatids are now at opposite poles Spindle disassembles Nuclear envelope forms around each set of sister chromatids Nucleolus reappears CYTOKINESIS begins at the end of this stage Chromosomes reappear as chromatin 29 Comparison of Anaphase & Telophase 30 “Activity: Mitosis Practice” worksheet (front side only) 31 32 33 Cytokinesis Means division of the cytoplasm Division of cell into two, identical halves called daughter cells 34 Mitotic Stages 35 Daughter Cells of Mitosis Have the same number of chromosomes as each other and as the parent cell from which they were formed Identical to each other, but smaller than parent cell Must grow in size to become mature cells (G1 of Interphase) 36 Identical Daughter Cells Chromosome number the same 37 Review of Mitosis 38 Name the Mitotic Stages: Interphase Telophase start Prophase Metaphase Anaphase 39 Eukaryotic Cell Division Used for growth and repair Produce two new cells identical to the original cell Cells are diploid (2n) Prophase Metaphase Chromosomes during Metaphase of mitosis Anaphase Telophase Cytokinesis 40 REMEMBER… PMAT + Cytokinesis = Mitotic Phase C y P M A T o t a l p a p o h p h p a h a h s a s a e s e s r e e n e e t o k i n e s i s 41 Mitosis Animation Name each stage as you see it occur? 42 Mitosis in Onion Root Tips Do you see any stages of mitosis? 43 Test Yourself over Mitosis 44 Name the Stages of Mitosis: Anaphase prophase Metaphase Interphase Prophase cytokinesis Telophase, Prophase Anaphase 45 Identify the Stages ? Prophase ? ? Metaphase Prophase Anaphase Anaphase ? ? Telophase ? ? Telophase 46 1. “Activity: Mitosis Practice” worksheet (back side) 2. CELL CYCLE worksheet and questions 3. Mitosis Worksheet #1-24 & #1-10 4. Mitosis QUIZ practice 47