Name____________
Human Genome Study Guide
1. What are sex chromosomes? What combination of sex chromosomes produces a
human female? A male?
2. What kind of cell determines the sex of a child?
3. What is a karyotype?
4. What are the different blood types? Which groups are said to be codominant? What
is codominant?
5. What is a pedigree and how are they used? Be able to read them, especially when
given a key.
6. Using an example, explain how a small change in a person’s DNA can cause a genetic
disorder.
7. What is a sex-linked disorder? Why are they more common in males than in
females? List some examples.
8. ______________ occurs when a male inherits an extra X chromosome.
________________ occurs when there is a trisomy of chromosome 21.
_______________ occurs when a woman inherits only one X chromosome.
9. Distinguish between sex-linked disorders and sex chromosome disorders.
10. Why could you conclude that the “xx” chromosomes is essential for the development
of a human embryo but the “y” chromosome is not.
11. What is the process scientist use to manipulate DNA?
12. How does gel electrophoresis work?
Don’t forget the genetics info that we learned for the last test….it will be on this test as
well. (ie. Punnett squares, homozygous, heterozygous, genotype, phenotype, haploid,
diploid.)