SKIN Hair shaft Receptor for touch pore Epidermis Sebaceous gland Dermis Arrector Pili muscle Subcutaneous Hair follicle Receptor for pressure Adipose tissue Sweat gland Epidermis -- bottom or basal layer continually reproduces new cells (Mitosis) -- top layer hardens because of Keratin, a fibrous waterproof protein -- thickest on palms of hands & soles of feet -- contains Melanocytes, that produce Melanin -- a pigment responsible for skin color Dermis -- contains elastic & collagen fibers -- contains nerve fibers & blood vessels Epidermis + Dermis = Cutaneous Membrane (Skin) FUNCTIONS OF THE SKIN 1. Protection -- considered our First Line of Defense against physical trauma, bacterial invasion, & fluid loss 2. Synthesis of Vitamin D -- contains a molecule that converts to Vit. D when exposed to Ultraviolet light 3. Sensory Reception and Communication -- helps us feel pressure, pain, hot & cold 4. Regulation of Body Temperature -- blood vessels constrict, & sweat gland become inactive Functions of the Skeletal System 1. Provides framework & gives us shape 2. Protects vital organs 3. Serves as levers for muscles & permits flexible movement 4. Stores minerals -- 99% of the body’s Calcium & 88% of the body’s Phosphorus is stored in the bones 5. Produces all the blood cells from the red bone marrow -- found in flat bone & ends of long bones Cranium Scapula Sternum Vertebrae Radius Carpals Metacarpals Phalanges Fibula Metatarsals Phalanges Face Clavicle Humerus Ribs Ulna Coxal Sacrum Coccyx Femur Patella Tibia Tarsals Types of Bones 1. Flat Bones -- Ex. skull or cranium; ribs; sternum; hip bones 2. Short Bones -- Cube-shaped -- Ex. wrists & ankles 3. Irregular Bones -- Vertebrae & facial bones 4. Long Bones -- humerus; radius, femur -- femur is the longest bone in the body Structure of Long Bones Epiphysis Ends of the bone Articular Cartilage Epiphyseal disk (growth plates) Yellow Marrow (contains fat) Diaphysis shaft Periosteum Tough connective tissue covering bones Endosteum Lines marrow cavity Epiphysis Compact Bone Marrow (medullary) cavity Spongy Bone (contains yellow marrow) BONE FORMATION Begins in the Fetus in about the 3rd month. -- Cartilage begins to be replaced with bone by the process of Ossification -- Osteoblasts (Bone Building Cells) become active & start producing Collagen. -- With the help of enzymes, Calcium salts are deposited between the osteoblasts. -- When this material hardens, the cells can no longer reproduce and are now called Osteocytes -- Closure of the epiphyseal discs occurs between the 16 & 25. -- Osteoclasts -- break down bone -- Bone is continually being broken down and built back up again. TERMS LIGAMENT -- connects bone to bone TENDON -- connects muscle to bone JOINTS -- union of two or more bones -- articulation -- Fixed -- Ex. Skull -- Limited -- Ex. vertebrae -- Moveable --Ex. shoulder, knee, hip Differences Male Pelvis Male -- smaller in size -- bones are denser -- Pelvic cavity more funnel shaped Female Female Pelvis -- greater flaring of the iliac bone -- pelvis is wider -- pelvic cavity is shallow -- bones are thinner & lighter JOINTS Function of Joints 1. Provides for expansion & molding in infants. 2. Allows for flexibility and movement. Types of Joints -- joints determine the amount of movement allowed 1. Synarthrosis -- immovable 2. Amphiarthrosis -- slightly moveable 3. Diarthrosis -- freely moveable -- also called a Synovial joint -- contains Synovial Fluid that acts as a cushion & allows for ease of movement -- Fluid is thick & colorless Gliding -- allows for sliding or twisting -- ankles & wrists Ball & Socket Hinge Pivot Hinge -- allows for movement in one direction (back & forth) -- elbows, knees, & fingers Pivot -- allows for rotation -- cervical vertebrae & proximal ends of ulna & radius Gliding Condyloid Saddle -- movement in 2 direction, but no rotation -- wrists & forearms, metacarpals & phalanges, & jaw Saddle -- allows for more movement (hand & thumb) Ball & Socket -- movement in many directions (hips & shoulders MUSCLES Types of Muscles 1. Skeletal -- voluntary -- striated -- make up the bulk of the human body 2. Visceral -- involuntary -- smooth -- stomach, intestines, blood vessels 3. Cardiac -- involuntary -- only found in the heart FASCIA -- fibrous connective tissue that covers muscles -- it extends out to become the Tendon -- the fascia layer closest to the muscle is called Epimysium Muscle fibers (cells) are arranged in bundles & work in groups -- Perimysium divides the muscles into bundles -- Endomysium is the fascia layer that covers each fiber Skeletal Muscle Function 1. Muscles & bones work as a system of levers 2. Muscles have two attachment sites -- Origin -- less moveable part -- Insertion -- put muscle into action 3. Many skeletal muscles function in pairs -- Prime Mover -- Synergists -- muscles that help the Prime Mover -- Antagonist 4. Muscles are in a partial state of contraction even when they are not in use -- this is called TONE 5. Muscle cells can be excited by: -- Mechanical means (you choose to move it) -- Chemical means (use of Neurotransmitters) -- Electrical means (nerve impulses) Movement of Sodium (Na+) & Potassium (K+) in and out of the cells Acetylcholine is the neurotransmitter involved here Nerve Conduction Na+ Na+ Na+ Na+ Na+ + + + - - K+ K+ + - K+ + - - + K+ K Na+ K+ K+ Na+ Neuron Negatively charged / Resting Potential Neurotransmitter is released by axon of previous Neuron / Action Potential Na+ K+ + + + + Na+ Na+ + + + + + - -+ - + - -+ Na Na Na + Na+ Na+ K+Na+ Na+ K+ K+ Acetylcholine K+ K+ K+ Na+ K+ K+ The Neurotransmitter causes cell membrane of receiving Neuron becomes permeable to Sodium (Na+) Na+ K+ K+ Na+ K+ + + + + + Na+ Na+ K+Na+ Na+ K+ K+ K+ Na+ moves into cell until saturated & Potassium (K+) moves out Neuron becomes Positively charged / Depolarization Na+ K+ + + Acetylcholinesterase + + + Na+ Na+ K+Na+ Na+ K+ K+ Enzyme is released by receiving Neuron Cell membrane reverts back to being impermeable to Na+ Sodium - Potassium Pump in cell membrane causes Na+ to move out and K+ to move back into cell Na+ Na Na+ Na+ Na+ ++ + - - + - + - + - K+ K+ K+ K+ K+ Na+ Na+ K+ K+ Neuron is now Negatively-charged once again / Repolarization 6. Muscles get their energy from ATP (Adenosine Triphosphate) released by oxidation -- oxidation is the burning of food (Glucose) -- Muscles store Oxygen as Myoglobin & glucose as glycogen As long as muscles have enough oxygen & nutrients the exercise is called AEROBIC (Endurance-type) -- if no oxygen is available, some ATP can be supplied by Anaerobic Respiration -- a waste product of this is Lactic Acid, which in elevated levels will eventually interfere with muscle contraction 7. Contraction of muscle fibers produce most of the heat required to maintain body temperature 8. Special proteins called ACTIN & MYOSIN allow muscle fibers to contract -- Calcium is need for the Actin & Myosin to slide over each other & form a bridge -- ATP is need for detachment Calcium ions Actin -- A Ca+ pump pulls Ca+ back into cell wall when no longer needed Relaxed muscle Myosin Contracted muscle TERMS Excitability -- capacity to respond to a stimuli Contractility -- capacity to undergo shortening & to change shape Elasticity -- the innate tension that causes the muscle to assume a desired shape regardless of how it is stretched Isotonic -- tension remains the same but muscle shortens (requires movement) Isometric -- no change in length, but great increase in tension (no movement) TYPES OF MOVEMENTS Elevation & Depression -- shrug shoulders Abduction (away from the midline) Adduction (toward the midline) Circular movements -- shoulders & hips Dorsiflexion -- pointing toes toward the head Plantar Flexion -- pointing toes downward Flexion (decrease in angle) Extension (increase in angle) Supination -- palm up Pronation -- palm down Inversion -- turning sole of foot inward Eversion -- turning sole of foot outward Temporalis Frontalis Orbicularis Oris Sternocleidomastoid Deltoid Triceps Brachii Pectoralis Biceps Brachii Vastus lateralis Sartorius External Oblique Rectus Femoris Vastus Medialis Occipitalis Trapezius Latissimus dorsi Gluteus medius Semitendenosus Gluteus maximus Semimembranosus Gastrocnemius Achilles tendon