BONES AND THE SKELETON IMAGES Human skeleton The skeleton of a human male in a sitting position. Credit: Wellcome Library, London. BIGPICTUREEDUCATION.COM Normal bone A scanning electron micrograph of normal bone. This sample is from a vertebra (a bone of the spine) of a healthy male. Credit: Professor Alan Boyde, Wellcome Images. Bone affected by osteoporosis A scanning electron micrograph of osteoporotic bone. This sample is from a vertebra (a bone of the spine) of an 89-year-old woman with osteoporosis. Credit: Professor Alan Boyde, Wellcome Images. BIGPICTUREEDUCATION.COM Bone affected by osteoporosis A thin slice of an osteoporotic vertebra (a bone of the spine) from an 89-year-old woman, showing damage to the structure of the bone. This image has been colour enhanced. Credit: Professor Alan Boyde, Wellcome Images. BIGPICTUREEDUCATION.COM Growing bone A region of growth (epiphyseal growth plate) in an immature thighbone. Cartilage is stained purple, and bone is stained yellow-green. The rapidly dividing cartilage cells within the purple band at the top form stacks that run parallel to the long axis of the bone. Below this zone, the cartilage becomes calcified and the cartilage cells (chondrocytes) die. Further down is the ossification zone, where the bone tissue is laid down. Credit: Karin Hing, Wellcome Images. BIGPICTUREEDUCATION.COM The epiphysis The ‘epiphysis’ is the rounded end of a long bone - the region of bone that forms joints with adjacent bones. The process seen here is ossification, the growth process that results in the generation of new bone. Calcification occurs during ossification. Credit: Spike Walker, Wellcome Images. BIGPICTUREEDUCATION.COM Compact bone Compact bone, from human femur. Transverse sections showing cross-sections and the arrangement of osteons and Haversian canals. Bone is made up of two types of tissue: the compact bone forms a shell around the spongy cancellous bone that makes up the marrow space in the centre. Compact bone provides strength and rigidity and is solid in appearance. It is composed of a layered matrix of organic substances and inorganic salts that form around an intricate network of vasculature called Haversian canals. Credit: Ivor Mason, KCL, Wellcome Images. BIGPICTUREEDUCATION.COM Human fingers The bones of the human fingers, wearing a ring. This image is a photograph of an X-ray attributed to L Ropner, 1897. Credit: Wellcome Library, London. BIGPICTUREEDUCATION.COM Composition of bone A diagram showing a cross-section of the composition of bone. Credit: Miles Kelly Art Library, Wellcome Images. BIGPICTUREEDUCATION.COM Female figure running Artwork of the figure of a woman running, revealing the skeleton beneath transparent skin. Credit: Oliver Burston, Wellcome Images. BIGPICTUREEDUCATION.COM Skelton of a man with numerous osseous growths The skeleton of a man, aged 39 years, which had numerous osseous growths of varied dimensions. From the Hunterian specimen in the Museum of the Royal College of Surgeons, no.1616a. Presented by Samuel George Shattock, Esq (1888-1889). Credit: St Bartholomew’s Hospital Archives and Museum, Wellcome Images. BIGPICTUREEDUCATION.COM Reusing our images Images and illustrations • All images, unless otherwise indicated, are from Wellcome Images. • Contemporary images are free to use for educational purposes (they have a Creative Commons Attribution, Non-commercial, No derivatives licence). Please make sure you credit them as we have done on the site; the format is ‘Creator’s name, Wellcome Images’. • Historical images have a Creative Commons Attribution 4.0 licence: they’re free to use in any way as long as they’re credited to ‘Wellcome Library, London’. • Flickr images that we have used have a Creative Commons Attribution 4.0 licence, meaning we – and you – are free to use in any way as long as the original owner is credited. • Cartoon illustrations are © Glen McBeth. We commission Glen to produce these illustrations for ‘Big Picture’. He is happy for teachers and students to use his illustrations in a classroom setting, but for other uses, permission must be sought. • We source other images from photo libraries such as Science Photo Library, Corbis and iStock and will acknowledge in an image’s credit if this is the case. We do not hold the rights to these images, so if you would like to reproduce them, you will need to contact the photo library directly. • If you’re unsure about whether you can use or republish a piece of content, just get in touch with us at bigpicture@wellcome.ac.uk.