The Cell and Cell Transport Anatomy and Physiology The Cell and Cell Transport • Functional anatomy – study of structures as they relate to function • We study a typical cell (composite cell) • Cell size – range from 7.5 µm to 150 µm – µm = 1 millionth of a meter; 1 x 10-6 meters Nerve Cells • Features – Surface is sensitive to stimuli – Has long extensions • Functions – Detects changes in environment – Transmits nerve impulses throughout body http://www.becomehealthynow.com/images/organs/n ervous/nerve_cell_bh.jpg Muscle Cells • Features – Elongated, threadlike – Contain tiny fibers that slide together • Functions – Contract to allow movement of body parts http://missinglink.ucsf.edu/lm/IDS_101_histo_resource/im ages/351Blabeled_copy.jpg • Features Red Blood Cells – Contains hemoglobin (attract and releases O 2) • Functions – Transports O2 in the bloodstream http://www.odec.ca/projects/2007/nand7t2/images/r bc.jpg • Features Gland Cells – Contain sacs that release secretions to the outside of the cell • Functions – Release hormones, enzymes, mucus, and sweat http://mwsu-bio101.ning.com/forum/topics/distincthuman-celltypes-1 Immune Cells • Features – Some can engulf other cells – Some manufacture antibodies – Some can destroy other cells • Functions – Recognize and destroy “nonself” cells (cancer, bacteria) http://www.jyi.org/articleimages/821/originals/img0.j pg Membrane bound organelles • • • • • • • Plasma membrane Endoplasmic Reticulum Golgi apparatus Lysosomes Peroxisomes Mitochondria Nucleus Non membrane bound organelles • • • • Ribosomes Cytoskeleton Cilia and flagella Nucleolus Plasma Membrane • Cell boundary; protein molecules serve as markers that identify cell’s purpose http://micro.magnet.fsu.edu/cells/plasmamembr ane/images/plasmamembranefigure1.jpg Endoplasmic Reticulum • Rough ER – ribosomes attached synthesize proteins that leave via Golgi apparatus • Smooth ER – synthesizes lipids in cell membranes, steroid horomones, and certain CHO http://www.sciencegateway.org/resources/biol ogytext/cb/org/rough_er-em.gif http://www.sciencegateway.org/resources/biology text/cb/org/smooth_er-em.gif Golgi apparatus • Synthsize CHO, combines it with a protein, & packages the product as globules of glycoprotein (proteins that contain oligosaccharide chains (glycan) covalently attached to polypeptide side-chains) http://www.beyondbooks.com/lif7 1/images/00016960.jpg Lysosomes • Digestive enzymes that break down worn cell parts and ingested particles http://www.cartage.org.lb/en/them es/sciences/zoology/animalphysiol ogy/anatomy/animalcellstructure/L ysosomes/lysosome.jpg Peroxisomes • Contain enzymes that detoxify harmful substances http://micro.magnet.fsu.edu /cells/peroxisomes/images/ peroxisomesfigure2.jpg Mitochondria • Catabolism (the set of pathways that break down molecules into smaller units and release energy); ATP synthesis http://microbewiki.kenyon.edu/ima ges/thumb/2/25/Mitochondria.gif/4 00px-Mitochondria.gif Nucleus • Genetic code which dictates protein synthesis http://www.frontiers-ingenetics.org/en/pictures/nucleus_1.jpg Ribosomes • Site of protein synthesis http://www.cbv.ns.ca/bec/science/cell/page11 a.gif Cytoskeleton • Framework to support the cell and organelles; functions in cell movement; forms cell extensions http://www.immediart.com/catalog/images/bi gger_images/SPL_6_P780110Fibroblast_cells_showing_cytoskeleton. jpg Cilia and flagella • Hair like extensions that serve to move substance over the cell or propel sperm cells http://www.pcdfoundation.org/im ages/Johnny%27s%20cilia%20 pic.jpg http://digitaldaily.allthingsd.com/files/2008 /01/sperm.jpg Nucleolus • Part of the nucleus; helps form ribosomes http://www.palaeos.com/Invertebrates/Lists/Imag es/nucleolus.jpg Fluid Mosaic Model • The current model of the plasma or cell membrane that we use. • It is a mosaic (made of many pieces) • Fluid – molecules are able to float around like icebergs http://micro.magnet.fsu.edu/cells/plasmamembrane/ima ges/plasmamembranefigure1.jpg • Hydrophillic = water lover • Hydrophobic = afraid of water Passive Transport • Requires no chemical energy • 4 types – Diffusion – Facilitated diffusion – Filtration – Osmosis Diffusion • Movement of particles from an area of higher concentration to an area of lower concentration • http://www.toltecint.com/how_dialysis_works /diffusion.jpg Facilitated diffusion • the spontaneous passage of molecules or ions across a biological membrane passing through specific transmembrane transport proteins. The facilitated diffusion may occur either across biological membranes or through aqueous compartments of an organism • http://www.williamsclass.com/SeventhScien ceWork/ImagesCellBricks/facilitatedDiffusion .jpg Filtration • movement of water and solute molecules across the cell membrane due to hydrostatic pressure generated by the cardiovascular system. Filtration is a mechanical or physical operation which is used for the separation of solids from fluids • http://upload.wikimedia.org/wikipedia/c ommons/thumb/8/86/Filtration_diagra m.svg/238pxFiltration_diagram.svg.png Osmosis • Osmotic Pressure – water potential of the two solutions • Hypertonic – higher salt concentration • Isotonic – same salt concentration inside and out • Hypotonic – lower salt concentration Osmosis • movement of water molecules across a partially-permeable membrane down a water potential gradient. More specifically, it is the movement of water across a partially permeable membrane from an area of high water potential (low solute concentration) to an area of low water potential (high solute concentration). – • http://en.wikipedia.org/wiki/Osmosis http://www.ndpteachers.org/perit/osmosis2.gif Active Transport • Movement against the concentration gradient (from low to high concentration) –Active Transport –Phagocytosis –Pinocytosis –Exocytosis Active Transport • Please print up to this point in the ppt. I will print copies of the additional slides for you!!!