Name_________________________ http://learn.genetics.utah.edu/content/begin/tour/mitosis.swf 1. What does diploid mean? What does haploid mean? 2. How does this site tell you to remember the difference between mitosis and meiosis? http://www.dnaftb.org/dnaftb/8/concept/index.html Click on Problem 3. What is the human diploid number? What is the human haploid number? http://www.uic.edu/classes/bios/bios100/lecturesf04am/lect16.htm 4. What is crossing over? 5. What does crossing over increase? http://www.biologycorner.com/bio1/meiosis.html 6. What is created in spermatorgenesis? 7. What is created in oogenesis? 8. How is spermatogenesis from oogenesis? (besides the cells that are created) http://www.ygyh.org/ds/whatisit.htm 9. Is there a cure for Down Syndrome? 10. What is the cause of Down Syndrome? 11. About how many people have Down Syndrome? http://www.ygyh.org/ds/cause.htm Click Continue in the bottom right corner to find the answers. 12. How many chromosomes do people with Down Syndrome have? How many chromosomes do most people have? 13. Write down 2 of the physical traits that people with Down syndrome have. 14. What goes wrong in meiosis that causes Down Syndrome? 15. Which is more likely to be the cause of Down Syndrome the egg or the sperm? 16. What causes non disjunction (the most common cause of Down Syndrome)? Karyotyping http://www.biology.arizona.edu/Human_Bio/activities/karyotyping/karyotyping.html 17. What process are the cells going through when you do a karyotype? 18. Label the identifying features of a chromosome. You will evaluate 3 patients' case histories, complete their karyotypes, and diagnose any missing or extra chromosomes. Click on “Patient Histories.” Read patient A’s history then click on “Complete Patient A’s Karyotype.” Missing chromosome order for Patient A. (for example if the first chromosome matches the 20th pair write down 20 etc) Patient A 1._______ 2._______ 3. _______ 4. _______ 5. _______ Answer the questions under "Interpreting the karyotype." A1 A2 Same for Patient B. 1. _______ 2. _______ 3. _______ 4. _______ 5. _______ 6. _______ 7. _______ 8. _______ B1 B2 Patient C. 1. _______ 2. _______ 3. _______ 4. _______ 5. _______ 6. _______ 7. _______ 8. _______ C1 C2 http://learn.genetics.utah.edu/content/disorders/w hataregd/ For each genetic disease describe the chromosome abnormality and a few characteristics of the disease. Syndrome Turner Klinefelter Cri du chat Chromosome Problem Characteristics Williams http://www.biologyinmotion.com/cell_division/index.ht mlPlace Clickthe on Practice Meiosis & follow the directions chromosomes or chromatids in each cell.