Anatomy & Physiology Part 2: Nervous System The Brain: • ~100 billion multipolar neurons • 3 major components: – The cerebrum largest part (associated with sensory & motor functions, higher mental functions) – The cerebellum (voluntary muscle movement & coordination) – The brain stem (connects & regulates viscera) Another part of the brain is the diencephalon. This is also associated with sensory functions. http://www.google.com/imgres Cerebrum: • There are 2 cerebral hemispheres. This is collectively called the cerebrum. • Gyri are ridges; sulci are grooves. • Fissures are deep grooves – Fissures divide the cerebrum into lobes. http://www.google.com/imgres Cerebrum Lobes: These are named for the bones they are under. 1. 2. 3. 4. 5. Frontal lobe Parietal lobe Temporal lobe Occipital lobe Insula • The corpus callosum is a “bridge” of nerve fibers that connect the 2 hemispheres. • The hemispheres generally mirror each other. There are 3 main areas of the cerebrum: • Cerebral Cortex • White Matter • Basal Nuclei Cerebrum: Cerebral Cortex: • Functions: speech, memory, logic, emotional responses, & voluntary movement The cortex includes: • Broca’s area: vocalization/formation of words • Speech area: language comprehension (meanings of words) http://www.google.com/imgres Cerebrum: White Matter: Basal Nuclei: • Contains nerve tracts that allow communication to occur between hemispheres and brain stem • a.k.a. basal ganglia • Gray matter • Regulate voluntary motor functions Diencephalon: • It contains the thalamus, hypothalamus, optic tracts pituitary gland, mammillary gland & pineal gland. • The thalamus is the central region of message relays; receiving all sensory info (except smell) & transmitting the signals to the appropriate location. – It produces awareness of sensations. http://www.google.com/imgres • The hypothalamus maintains homeostasis & links the NS to the endocrine system. It regulates: – Heart rate & blood pressure – Body temperature – Water & electrolyte balance – Hunger & body weight – Stomach & intestinal secretions & movement – Sleep & wakefulness – Production of stimulants for the pituitary gland Diencephalon: • The hypothalamus includes the limbic system and controls emotional responses & expression; as a result, it guides behavior to increase the chance of survival. Other glands part of the Diencephalon: • Pituitary gland (hormones) • Pineal gland (sleep regulation) • Choroid plexuses (capillaries that secrete CSF) Brain Stem: • Connects the spinal cord to the cerebrum Midbrain • Includes the midbrain, pons & medulla oblongata • The midbrain contains reflex centers (visual & auditory http://www.google.com/imgres • The pons is between stem & oblongata; relays sensory impulses & regulates rate & depth of breath. • The medulla oblongata is below the pons • The medulla oblongata is associated with coughing, sneezing, swallowing & vomiting reflexes. • It controls heart rate, blood pressure, and breathing • The reticular formation is a network of nerve fibers that are throughout the midbrain, pons & medulla oblongata. • This regulates wakefulness (increased activity increases awareness; decreased activity induces sleep). • If this is injured, this causes unconsciousness; if the person cannot be aroused, a comatose state (coma) results. Cerebellum: • Integrates & coordinates sensory info & skeletal muscles; helps to maintain posture. • Injury to this area will cause tremors (involuntary movements), inaccurate movements, staggering walk, muscle tone loss or equilibrium disturbance. Protection of CNS: Meninges • The CNS is surrounded by bones, membranes & fluids (skull contains the cranial cavity which contains the brain, etc.). • The membranes of the CNS are the meninges (between bones & soft tissues). • These protect the brain & spinal cord. • There are 3 layers to the meninges: dura mater, arachnoid mater, & pia mater. http://www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/19080.jpg Meninges: Dura Mater: Arachnoid Mater: • outermost layer • • found within the cranial cavity, surrounds skull bones, & extends inward between brain lobes Thin membrane without a blood supply • Between dura mater & pia mater • Covers brain & spinal cord • Surrounds the spinal cord & ends as a sac right below the cord (but is not attached to the vertebrate). • Between the arachnoid mater & pia mater is the subarachnoid space. The cerebrospinal fluid (CSF) is contained here. – This is a clear watery fluid that bathes the brain & spinal cord. Pia Mater: • The innermost layer of the meninges • Covers the brain & spinal cord and follows their surfaces closely Spinal Cord: • This is a nerve column that goes from the brain into the vertebral canal. • Consists of 31 segments & 31 pairs of spinal nerves • There are 2 enlargements: the cervical enlargement contains the nerves for the upper limbs; the lumbar enlargement contains the nerves for the lower limbs. http://www.google.com/imgres Spinal Cord with Meninges: http://www.google.com/imgres PNS: Cranial Nerves: • There are 12 pairs of cranial nerves: 1. Olfactory nerves (I): sense of smell 2. Optic nerves(II): vision (eyes to brain) 3. Oculomotor nerves (III): eye muscle movement (somatic & autonomic) 4. Trochlear nerves (IV): eye movement; smallest cranial nerves 5. Trigeminal nerves (V): contain ophthalmic, maxillary, & mandibular nerves; mixed nerves; largest cranial nerves. 6. Abducens nerves (VI): aids in eye muscle movement 7. Facial nerves (VII): taste receptors; stimulate salivary & tear gland secretions (autonomic) 8. Vestibulocochlear nerves (VIII): maintain equilibrium & enable hearing (ear) 9. Glossopharyngeal nerves (IX): swallowing; mixed nerves; associated with the tongue & pharynx. 10. Vagus nerves (X): speech & swallowing; mixed (autonomic & somatic) 11. Accessory nerves (XI): cranial & spinal 12. Hypoglossal nerves (XII): tongue, speaking, chewing & swallowing. See textbook for summary of cranial nerves. PNS: Spinal Nerves: • Come from the spinal cord • Grouped according to their location: 1. Cervical nerves (#C1 to C8): 8 pairs 2. Thoracic nerves (#T1 to T12): 12 pairs 3. Lumbar nerves (#L1 to L5): 5 pairs 4. Sacral nerves (#S1 to S5): 5 pairs 5. Coccygeal nerves (Co): 1 pair • See textbook summary of these spinal nerves. Autonomic Nervous System: • Functions independently (autonomous), meaning without conscious thought • Controls visceral functions • Contains the parasympathetic & sympathetic divisions • The parasympathetic division functions during restful conditions while the sympathetic division functions during emergency, stressful & energy spending situations. • Look up in text or online! • Know the following: Huntington’s Disease, Parkinson’s Disease, Ataxia, Meningitis, Encephalitis, Hydrocephalus, Blood brain barrier, Concussion, Contusion, Intracranial hemorrhage, cerebral edema, CVA, hemiplegia, TIA, Cerebral palsy, Spina bifida, and Senility • • This slide show was developed by Dana Halloran, Cardinal Mooney High School, Sarasota, FL. • • • Used with her personal permission, adapted and amended by Rosa Whiting, Manatee School for the Arts, Palmetto, FL.