For this Activity You will Need:
Blue Colored Pencil
Red Colored Pencil
Green Colored Pencil
Lead Pencil

• THINK! – What is the goal of the Cell
Cycle? Fill the answer into the box on your graphic organizer.
– To create 2 new cells each with the SAME number of DNA molecules (chromosomes) as the original cell and same size

• 1. Interphase
– Cell Grows
– DNA Doubles

Centrioles • A. Prophase (P=Prepare)
– Chromatin coils into duplicated chromosomes
– Nuclear Membrane disappears
– Spindle fibers shoot out from centrioles

Spindle Fibers
Duplicated
Chromosomes
• B. Metaphase (M=Middle)
– Spindle fibers pull duplicated chromosomes to the middle of the cell

• C. Anaphase (A=Apart)
– Duplicated chromosomes split at centromere
– Fibers pull chromosomes to opposite ends of cell

• D. Telophase (T=Tear)
– Chromosomes uncoil into chromatin
– Nuclear membrane reappears
– Spindle fibers disappear

• 3. Cytokinesis
– Cytoplasm & organelles divide
– Cell splits into two new cells

Visualizing Mitosis
• VIDEO
– Mitosis - Hybrid Medical Animation
– Mitosis courtesy of Protein Lounge Animations
– Mitosis to Music http://wormclassroom.org/files/worm/CellDivision.swf
– Animal Cell Mitosis in Real Time
– Breast Cancer Cells Dividing
– Glencoe Mitosis Animation
• Websites
– Mitosis with Musichttp://www.loci.wisc.edu/outreach/bioclips/CDBio.html
– Brain-Pop Clip (Mitosis) http://glencoe.mcgrawhill.com/sites/007877800x/student_view0/brainpop_movies.html
– Cells Alive http://www.cellsalive.com/mitosis.htm
– Biology Corner http://www.biologycorner.com/bio1/cellcycle.html