1
Curriculum Vitae: Dr. Anton Gartner
Reader / CR-UK Research Fellow (since August 2004) /Wellcome Trust Senior
Research Fellow (from August 2010)
Personal:
Name:
Date of birth:
Place of birth:
Nationality:
Marital Status:
Children:
Anton Gartner
July 7th, 1967
Vienna, Austria
Austrian
married
Isabel Gartner (Oct 3rd, 1997)
Tobias Gartner (August 25th, 2000)
Address private:
81 Camphill Rd.
Broughty Ferry, DD5 2NA, UK
Tel.: +44 (0) 1382 736215
E-mail: ulrike.gartner@web.de
Address work:
Wellcome Trust Centre for Gene Regulation and Expression
The University of Dundee
Dow Street
Dundee, DD1 5EH, UK
Tel.: +44 (0)1382 385809
E-mail: a.gartner@dundee.ac.uk
http://www.dundee.ac.uk/biocentre/gartner/index.htm
Education:
1977-1985
85-90
89
Sept. 90
Oct. 90
Oct. 90-Sept.94
Nov. 92-Feb. 93
Oct. 94-Sept.95
July 95
Gymnasium Neusiedl/See, Austria
Study of Biology at the University of Vienna, Austria
Diploma thesis “Identification of plant cell-cycle genes”. Supervisor: Dr. Erwin
Heberle-Bors, Institute for Microbiology and Genetics, University of Vienna,
Austria
Part II examinations with special options in Genetics and Biochemistry,
Graduation (Master of Science) from the University of Vienna, Austria
PhD. project at the Institute for Molecular Pathology, Vienna, Austria
Research topic: Studies on the pheromone dependent MAP kinase pathway in S.
cerevisiae. Supervisors: Dr. Gustav Ammerer and Dr. Kim Nasmyth
Continuation of the PhD. project at the Institute for General Biochemistry and
Molecular Cell Biology, University of Vienna, Austria
Visit at the University of North Carolina in Dr. Beverly Errede's lab, Chapel Hill,
USA
Social Service (Zivildienst), Working as a nurse in a unit for internal medicine at
the Rudolfsspital, Vienna, Austria
Graduation (PhD) from the University of Vienna, Austria
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Previous positions:
Oct. 95-Jan 97
From Feb. 97
Dec. 99-March 00
April 00-July 04
Since Aug. 2004
June 2009
Since Feb. 2010
From Aug. 2010
Post Doctoral Scientist and Teaching Assistant at the Institute for General
Biochemistry and Molecular Cell Biology, University of Vienna, Austria
Post Doctoral Scientist in the Laboratory of Dr. Michael Hengartner, Cold Spring
Harbor Laboratory, New York, USA
Visitor in the lab of Dr. Michael Glotzer at the Institute for Molecular Pathology,
Vienna
Junior Group Leader at the Max Planck Institute for Biochemistry in the
Department of Cell Biology, Munich, Germany
Lecturer, CRUK Career Development Award Fellow, University of Dundee,
College of Life Sciences, Wellcome Trust Centre for Gene Regulation and
Expression, UK
Successful Tenure Review University of Dundee
Reader, CRUK Career Development Award Fellow, University of Dundee, College
of Life Sciences, Wellcome Trust Centre for Gene Regulation and Expression, UK
Reader, Wellcome Trust Senior Research Fellow, University of Dundee, College
of Life Sciences, Wellcome Trust Centre for Gene Regulation and Expression, UK
Original scientific publications
Master Thesis, PhD and Postdoctoral Work
1) J. Györgey, A. Gartner, K. Nemeth, Z. Magyar, H. Hirt, E. Heberle-Bors and D. Dudits. (1991). Alfalfa heat
shock genes are differentially expressed during somatic embryogenesis. Plant Mol. Biol. 16, 999-1007.
2 ) H. Hirt, M. Mink, M. Pfosser, L. Börge, J. Györgey, C. Jonak, A. Gartner, D. Dudits and E. Heberle Bors.
(1992). Alfalfa Cyclins: Differential Expression during the Cell cycle and in Plant Organs. The Plant Cell, 4,
1531-1538.
3) H. Hirt, A. Gartner, E. Heberle-Bors. (1992). An Alfalfa cDNA encodes a protein with similarity to human
snRNP-E. Nuc. Acid. Res., 20, 613.
4) A. Gartner, K. Nasmyth and G. Ammerer. (1992). Signal transduction in S. cerevisiae requires threonine
and tyrosine phosphorylation of Fus3 and Kss1. Genes and Development, 6, 1305-1318.
5) B. Errede, A. Gartner, Zhaoqing Zhou, K. Nasmyth and G. Ammerer. (1993). A pheromone induced kinase
cascade in S. cerevisiae: activation of the Fus3 kinase by the Ste7 kinase in vitro. Nature, 362, 261-264.
6) Zhaoqing Zhou, A. Gartner, R. Cade G. Ammerer and B. Errede. (1993). Pheromone induced signal
transduction in S. cerevisiae requires the sequential function of three protein kinases. Mol. Cell Biol., 13,
2069-2080.
7) M. Peter, A. Gartner, J. Horecka, G. Ammerer and I. Herskowitz. (1993). Far1 links the signal transduction
pathway to the cell cycle machinery in yeast. Cell, 73, 747-760.
8) C. Wilson, N. Eller, A. Gartner, O. Vincente, E. Heberle-Bors. (1994). Isolation and characterization of a
tobacco cDNA clone encoding a putative MAP kinase. Plant Mol. Biol., 23, 543-551.
9) C. Doi, A. Gartner, G. Ammerer, H. Shinkawa, B. Errede, K. Suigimoto and K. Matsumoto. (1994). A
protein phosphatase promotes adaptation to pheromone response in S. cerevisiae. EMBO J., 13, 61-70.
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10) A. Gartner*, A. Jovanovic, D-I. Jeoung, S. Bourlat, F. Cross and G. Ammerer. (1998). Pheromone
dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of the
Cdc28/Cln2 kinase, in vivo. Mol. Cell Biol., 18, 3681-3691.
*Corresponding author
11) A. Gartner, S. Milstein, S. Ahmed J. Hodgkin and M. Hengartner. (2000). A conserved checkpoint
pathway mediates DNA damage-induced apoptosis and cell cycle arrest in C. elegans. Mol. Cell, 5, 435-444.
Publications as independent group leader
12) S. Ahmed, A. Alpi, M. Hengartner and A. Gartner. (2001). C. elegans RAD-5/CLK-2 defines a new DNA
damage checkpoint protein. Current Biology, Dec 11, 11(24): 1-20.
13) B. Schumacher, K. Hofmann, S. Boulton and A. Gartner. (2001). The C. elegans homolog of the p53
tumor suppressor is required for DNA damage induced apoptosis. Current Biology, Oct 30; 11(21): 1722-7.
14) SJ. Boulton, A. Gartner, J. Reboul, P. Vaglio, N. Dyson, DE. Hill, M. Vidal. (2002). Combined Functional
Genomic Maps of the C. elegans DNA Damage Response. Science, Jan 4, 127-131.
15) U. Grueneberg, M. Glotzer, A. Gartner, EA. Nigg. (2002). The CeCDC-14 phosphatase is required for
cytokinesis in the Caenorhabditis elegans embryo. J. Cell Biol.,158(5): 901-14.
16) R. Hofmann, S. Milstein, S. Boulton, J. Ye, J. Hofmann, L. Stergiou, A. Gartner, M. Vidal , and M.
Hengartner. (2002). Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for
genome stability and EGL-1-mediated apoptosis. Current Biology, 12(22): 1908-18.
17) A. Alpi, P. Pasierbek, A Gartner, J. Loidl. (2003). Genetic and cytological characterization of the
recombination protein RAD-51 in Caenorhabditis elegans. Chromosoma, 112(1): 6-16
18) SJ. Boulton, JS. Martin, J. Polanowska, DE. Hill, A. Gartner and M. Vidal. (2004). BRCA1/BARD1
orthologues required for DNA repair in Caenorhabditis elegans, Current Biology. 14(1): 33-9.
19) C. Wicky, A. Alpi, A. Rose, A. Gartner* and F. Müller. (2004). Multiple genetic pathways involving C.
elegans him-6/Blooms, mre-11, rad-51 and top-3 are needed to maintain genome stability in germ line, Mol.
Cell Biol. 24(11): 5016-27.
*Co-corresponding author
20) B. Schumacher, C. Schertel, N.Wittenburg, S. Tuck, S. Mitani, A. Gartner*, B. Conradt and SC. Shaham.
(2005). C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.
Cell Death Differ., 12(2): 153-61
*Co-corresponding author
21) B. Schumacher, M. Hanazawa, MH. Lee, S. Nayak, K. Volkmann; R. Hofmann, M. Hengartner, T. Schedl
and A. Gartner (2005).Translational Repression of C. elegans p53 by GLD-1 regulates DNA damage
induced apoptosis. Cell 120: 357-368
22) B. Meier, I. Clejab, Y. Liu, M. Lowden, A. Gartner, J. Hodgkin and S. Ahmed (2006). trt-1 Is the
Caenorhabditis elegans Catalytic Subunit of Telomerase. PLoS Genetics, Feb 10; 2(2)
23) A. Woodward, T. Göhler, M. Gloria Luciani,, M. Oehlmann, X. Ge, A. Gartner, D. Jackson and J. Blow
(2006) Excess Mcm2-7 license dormant origins of replication for use when replication fork progress is
inhibited, J. Cell Biol., Jun 5; 173(5): 673-83
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24) V. Jantsch, L. Tang, P. Pasierbek, A. Penkner, S. Nayak, A. Baudrimont, T. Schedl, A. Gartner, J. Loidl
(2007). Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous
chromosome pairing. Mol Biol Cell, Dec; 18(12): 4911-20.
25) H. Lee, LJ. Cho, N. Lambacher, J. Lee, SJ. Lee, TH. Lee, A. Gartner, HS. Koo. (2008). The C. elegans
AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and required for resistance to oxidative
stress and for normal motility and foraging behavior. J. Biol. Chem., Apr 11;
26) S. Greiss, B. Schumacher, K. Grandien, J. Rothblatt, A. Gartner. (2008). Transcriptional profiling in C.
elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family. BMC
Genomics. Jul 15; 9: 334.
27) J. Mouysset, A. Deichsel, S. Moser C. Hoege, A. Hyman, A. Gartner, T. Hoppe. (2008). Cell cycle
progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication. Proc Natl Acad Sci,
USA, Sep, 105(35): 12879-84.
28) S. Greiss, J. Hall, S. Ahmed, A. Gartner. C. elegans SIR-2.1 translocation is linked to a pro-apoptotic
pathway parallel to cep-1/p53-like during DNA damage induced apoptosis (2008) Genes & Development,
Oct, 22(20): 2831-41.
29) S. Moser, S. von Elsner, I. Buessing, A. Alpi, R. Schnabel, A. Gartner. (2009). Functional Dissection of
C. elegans CLK2/TEL2 cell cycle defects during embryogenesis and germ line development, PLOS
Genetics, April 5(4)
30) B. Meier, L. Barber, Y. Liu Y, I, Clejan, S. Boulton, A. Gartner*, S. Ahmed.* (2009), The MRT-1 nuclease
is required for DNA cross link repair and telomerease activity in vivo in C. elegans, EMBO J. 28(22):354963.
*equal senior author contribution with S. Ahmed
31) S. Greiss, and A. Gartner. (2009), Sirtuin phylogeny and structural conservation Mol Cells. 2009
Nov;28(5):407-15.
32) SJ. Lee, A. Gartner, M. Hyun, B. Ahn, and HS. Koo. (2010), A Werner syndrome protein in C. elegans
functions upstream of ATR and ATM in response to DNA replication inhibition and double-strand DNA
breaks, Plos Genetics Jan, 6(1):e10000801. .
33) S. Ito, S. Greiss, A. Gartner and WB. Derry. (2010), kri-1 regulates C. elegans germ cell death in a novel,
cell non-autonomous manner, Current Biology Feb 23;20(4):333-338.
34) C. MacKay, A. Déclais, C. Lundin, A. Agostinho, A. Deans, T. MacArtney, K. Hofmann, A. Gartner, S.
West, T. Helleday, D. Lilley and J. Rouse (2010). Identification of KIAA1018/FAN1, a DNA repair nuclease
recruited to DNA damage by monoubiquitinated FANCD2. Cell, 142(1)65-76
35) A. Bailly, A. Freeman, J. Hall, A. Déclais, A. Alpi, D. Lilley, S. Ahmed and A. Gartner (2010). The C.
elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair,
Plos Genetics, 6(7): e1001025.
36) R. Rutkowski, R Dickinson, G. Stewart, A. Craig, M. Schimpl, S. Keyse, and A. Gartner (2011) ERK
signalling is activated by irradiation and positively regulates CEP-1/p53 dependent apoptosis in C. elegans,
Plos Genetics, 7(8): e1002238
37) E. Pourkarimi, S. Greiss and A. Gartner (2011) Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization
is not consistent with the current model for C. elegans apoptosis induction, Cell Death and Differentiation,
Sept. 2, (Epub) cdd.2011.104
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38) M. Larance, AP. Bailly, E. Pourkarimi, RT. Hay, G. Buchanan, S. Coulthurst, DP. Xirodimas, A. Gartner
and AI. Lamond (2011) SILAN: Stable Isotope Labeling with Amino acids in Nematodes, Nature Methods,
under revision. Co-corresponding author Aug. 28, 7(8), e1002238
39) André Franz, Michael Orth, Paul A. Pirson, Remi Sonneville, Anton Gartner, Julian Blow Olaf
Stemmann, and Thorsten Hoppe (2011). CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin
Dissociation to Ensure Faithful DNA Replication, Mol. Cell, Oct 7, 44:85-96.
40) R. Sonneville, M. Querenet. A. Craig, A. Gartner* and J. Blow (2011). The dynamics of replication
licensing in live C. elegans embryos, in press Journal of Cell Biology *Co-corresponding author
Scientific reviews and bookchapters
PhD and Postdoctoral Work
41) A. Gartner. (1994). The role of protein phosphatases in the adaptation to the pheromone response in
yeast. In Advances in Protein Phosphatases; Leuven University Press 1994, 153-162.
42) A. Gartner and M. Hengartner. (1997). Genetic approaches to programmed cell death in C. elegans. In
‘When Cells Die’; John Wiley and Sons, Publications 1997, 131-146.
Publications published as independent group leader
43) A. Gartner, A. Alpi and B. Schumacher. (2003). Programmed Cell Death in C. elegans, Stefan Grimm
ed. Bios
44) B. Schumacher, A. Alpi and A. Gartner. (2003). Cell cycle: Check for asynchrony, Current Biology,
R560-R562.
45) A. Gartner. (2003). Genome-wide genetic screening by RNAi - a glimpse of the future, The ELSO
Gazette, Vol 14, April
46) A. Gartner, AJ. MacQueen and AM. Villeneuve. (2004). Methods for analyzing checkpoint responses in
Caenorhabditis elegans, Methods in Molecular Biology, entitled "Checkpoint Controls and Cancer". Methods
Mol. Biol., 280: 257-74.
47) AM. Leroi, A. Bartke, G. De Benedictis, C. Franceschi, A. Gartner, E. Gonos, ME. Feder, T. Kivisild, S.
Lee, N. Kartal-Ozer, M. Schumacher, E. Sikora, E. Slagboom, M. Tatar, Al Yashin, J Vijg, B. Zwaan (2005).
What evidence is there for the existence of individual genes with antagonistic pleiotropic effects. Mech.
Ageing Dev., 126(3): 421-9.
48) B. Schumacher and A. Gartner. (2006). Translational regulation of p53 as a potential tumor therapy
target Future Oncol., 2(1), 145-153
49) B. Meier and A. Gartner. (2006). Meiosis: Checking Chromosomes Pair up Properly. Current Biology,
R249-R251
50) A. Gartner, PR. Boag and TK. Blackwell (2008). Germline Survival and Apoptosis, WormBook, ed. The
C. elegans Research Community, WormBook, Sept; 1-20
51) A. Bilitou, J. Watson, A. Gartner and S.Ohnuma. (2009). The NM23 family in development. Molecular
and Cellular Biochemistry. Sept; 329 (1-2):17-33
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52) R. Rutkowski, K. Hofmann, A. Gartner. (2010). Phylogeny and Function of the Invertebrate p53
Superfamily, Cold Spring Harbor Persepect. Biol. 2010 Jul; 1; 2(7) Epub May5.
53) R. Rutkowski, K and A. Gartner. (2010). Tagging the dead a bridging factor for Caenorhabditis elegans
phagocyte receptors. Nature Cell Biol. Jul; 12(7) 638-640.
54) A. Bailly and A. Gartner. (2011). C. elegans DNA damage responses in “Molecular Determinants of
Radiation Response”, Springer press, March 23rd 2010
55) A. Craig S. Moser AP. Bailly and A. Gartner. (2011). “Methods to study C. elegans DNA damage
responses” in press, in the ‘Methods in Cell Biology’ series,
56) A. Bailly and A. Gartner. (2011). Germ cell apoptosis and DNA damage responses, in “The C. elegans
germ line”, Springer press, in press
57) R. Rutkowski, K and A. Gartner. (2012) “The shark in us: Learning about the evolution of the p53
regulatory circuit”, cell cycle, in press
Patent Applications
M. Hengartner, A. Gartner and S. Milstein. (1998). Damage induced apoptosis. US patent application No.
60/090,507
Fellowships and Awards
Max Kade fellowship (Feb 1997, declined), Austria, USA
EMBO long-term fellowship (June 1997), Europe
Schroedinger fellowship (April 1999), Austria
CR-UK Career Development Award (December 2003), UK
Wellcome Trust Senior Research Fellowship (April 2010), UK
Grants
Far1 regulation in pheromone dependent cell cycle arrest in S. cerevisiae (Jubiläumsfonds der
österreichischen Nationalbank 1996), Austria
Genetic and Molecular Analysis of DNA Damage induced Apoptosis and Cell Cycle Arrest in C. elegans
(Deutsche Forschungsgemeinschaft 2000), Germany
Analysis of meiotic, apoptosis-inducing checkpoint pathways by genomics-based, forward genetic and two hybrid
approaches in C. elegans (Deutsche Forschungsgemeinschaft 2001), Germany
Genetic and Molecular Analysis of DNA Damage induced Apoptosis and Cell Cycle Arrest in C. elegans
(Deutsche Forschungsgemeinschaft 2003), Germany
C11852/A4500 CR-UK Career Development Award Elucidation of DNA damage checkpoint pathways by C.
elegans genetics CR-UK Career Development Award 2003). £955,885 (August 2004 - August 2010), UK
C11852/A5991 CR-UK Project Grant (May 2005), Elucidation of Novel Negative Regulators of DNA Damage
Induced Apoptosis Using C. elegans Genetics. £130,802 (Jan. 2006 - Jan. 2009), UK
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Association for International Cancer Research (Nov. 2005), Combined biochemical and genetic approach to
elucidate sir-2 histone deacetylase function in C. elegans DNA damage induced apoptosis. £81,030 (Oct. 2006 Oct. 2009), UK.
Parkinson Disease Society (March 2006), “Elucidation of PINK-1 and LRRk2 function in Parkinson disease by a
combined genetic and biochemical approach in the C. elegans model system” £151,091 (Oct. 2006 - Oct. 2009)
(shared with Dario Alessi), UK
081923/Z/07/Z Wellcome Trust (April 2008 - April 2011), Combined genetic and biochemical C. elegans based
approach to understand differential substrate recognition and the mode of translational repression of the
conserved STAR mRNA binding protein GLD-1 £331,185, UK
COST EU travelling grant (shared with ~25 labs in Europe, from 2008) ca £350,000, EU
C11852/A8052 4 years CR-UK Studentship (Starting from August 2007) ca £120,000, UK
H-0709 Parkinson’s Disease Society 3 years studentship (August 2008 - August 2011), £85,000, UK
G-0912 UK Parkinson Disease Society (Jan 2010), “Establishing and Exploiting C. elegans as a Model for
Parkinson’s” £196,322 (Jan 2010-Jan 2013), UK
0909444/Z/09/Z Wellcome Trust Senior Research Fellowship (May 2010), “ Combined genetic and biochemical
approaches to uncover and characterize redundant factors in late stages of recombinational repair” £1427, 423
(Aug. 2010-Aug 2015).
Reviewing
I reviewed manuscripts for
Aging Cell, Cell, Cell Death and Differentiation, Current Biology, Development, EMBO J., Experimental
Gerontology, FEBS letters, Genes and Development, Genetics, Journal of Cell Science, MCB, Nature,
Nature Cell Biology, Nature Review Cell Biology, Oncogene, Plos Genetics, Plos One, and Science. I also
reviewed grants for CR-UK, the BBSRC, the MRC, the Wellcome Trust, the Parkinson Disease Society, for
the German DFG and the Boehringer Ingelheim Fonds, for the Swiss National Fonds, and junior and senior
ERC grants for the European Science Foundation. Currently I review around 24 papers and grant application
per year. In addition, I reviewed ~ 12 grants/ year for the Helsinki panel (see below). I also acted as reviewer
for the Canadian Terry Fox New Frontiers Program Project. I acted as a reviewer for Tenure Decisions for the
Clare Hall laboratories (2009, 2010) and for the Danish Biotechnology Research and Innovation Centre
(2011).
Service in review panels
German DFG study section, Bonn, 2005 Germany
German Landesstiftung Baden Wuertemberg, Stuttgart 2005 Germany
EU COST review panel, Brussels, May 2008, EU
Finnish Academy of Sciences, Biomedicine I, review panel June 2008), Helsinki, Finland
Finnish Academy of Sciences, Biomedicine I, review panel June 2009), Helsinki, Finland
German Landesstiftung Baden Wuertemberg, Stuttgart July, 2009 Germany
Finnish Academy of Sciences, Biomedicine I, review panel June 2010), Helsinki, Finland
Canadian Terry Fox New Frontiers Program April 2010
Service as PhD examiner
University of Dundee
Kathryn L. Ball lab, 2006
Frances Fuller Pace lab, 2007
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Jean-Christophe Bourdon lab, 2008
Julian Blow lab, 2008
IFROM Milano, Italy
Fabrizio d'Adda di Fagagna lab, Jan 2009
University of Edinburgh Hiro lab, Mai 2010
University of Copenhagen Soerensen lab, Jan 2011
University of Cambridge Miska lab, Feb 2011
Service as external PhD adivsor
Univ. of Zuerich, Switzerland
Michael Hengartner, August 2009
Service on CLS (College of Live Sciences) committees and
administrative roles
Deputy to Tom Owen Hughes for Wellcome Trust Centre for Gene Regulation and Expression, PhD program
Responsible for Wellcome Trust Centre for Gene Regulation and Expression Summer School.
Member of the CLS planning committee for Integrated Masters Degrees
Responsible for Wellcome Trust Centre for Gene Regulation and Expression recommendations for Dundee
undergraduate Curriculum
Deputy to Michael Start for Link to School of Learning and Teaching
Service in national and international committees
I was in the organization committee for the 2004 European Worm Meeting.
Management Committee Member of EU Cancer and Control of Genomic Integrity (CANGENIN) action.
University of Dundee representative for the Scottish University of Life Sciences Alliance (SULSA) for Cell
Biology.
From Jan 2012 Committee member of the UK Genome Stability Network
Teaching and Supervising
1997
“Biochemisches Praktikum für Fortgeschrittene” (biochemical course for advanced students),
University of Vienna, Department of Biochemistry,
2000 to 2003
“Vienna Worm Course” (University of Vienna, Department of Cytology, with Verena Jantsch).
Annual 2 weeks practical course and students seminar series on C. elegans
2000 to 2004
Taking care of rotation students at the MPI for Biochemistry (“Tübinger Studenten”). On
average I had 4 rotation students per year for 6 to 12 weeks each.
Dundee, Wellcome Trust Superseminar
Dundee Cell Biology Course (2 lectures)
Dundee Developmental Genetics Course (3 lectures, two further lectures were given by my
Post Doc Rachael Rutkowski 2007-2010)
Two lectures 4th year Genomics Course
Since 2004
Since 2006
Since 2007
Since 2010
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Since 2010
Since 2007
Three hours (lecture and paper discussion), 4th year Developmental Biology Module,
Invertebrate Development.
three lectures, Dundee Masters Course in Cancer Biology (DNA repair)
Annual lecture at the ENS Lyon, France
Jan 2009
Three lectures at the Pasteur Institute, Paris, France
Diploma Students
2003-2004
Katrin Volkman (PhD thesis at GSF, Munich Germany, now Sanger Centre, UK)
2004-2005
Nils Lambacher (Research Technician, Centre for Genome Damage and Stability,
UK)
2011-2012
Joerg Weiss
6 Month Rotation Students
2006
Magali Billet, Université des Sciences et Technologies de Lille
(Novartis Institutes for BioMedical Research, Basel Switzerland from 2007)
2007
Adriana Milicov, Université des Sciences et Technologies de Lille
(Novartis Institutes for BioMedical Research, Basel Switzerland from 2008)
Honours Students
2005/2006
2008/2009
2009/2010
2010/2011
2011/2012
Nicole Heppel (PhD student, Ducan Baird, Cardiff)
Alexander v. Wiliamowitz-Moellendorff (PhD student, MRC unit, Dundee)
Saif El Din Shehata (PhD student, MRC unit, Dundee)
Goeffrey Denwood (PhD student, Ninewells Hospital)
Markus Doll
PhD students
2000 to 2004
Arno Alpi (Principal Investigator, Scills CLS Dundee, UK, from Sept 2009)
Björn Schumacher (Principal Investigator, University of Cologne, Germany, since
Jan. 2009)
2003 to 2008
Sebastian Greiss (funded by CR-UK, AICR and Dundee CLS, Post Doc till June, 2009)
Post Doc with Jason Chin LMB, University of Cambridge)
Aymeric Bailly (funded by CR-UK, and Dundee CLS, Post Doc in my lab till June 2010,
Sandra Moser funded by CR-UK and Dundee CLS) (Post Doc with Jason Swedlow,
CLS Dundee, since 2008)
Since 2007
Ehsan Pourkarimi (funded by CR-UK)
Alper Akay (funded by a Wellcome Trust project grant)
Since 2008
Neda Masudi (funded by the Parkinson’s Disease Society)
Ana Agostinho (funded by BBSRC studentship to Dundee CLS)
Post Docs
10
2001-2002
co-advising Ulrike Grueneberg (Principal Investigator and CR-UK Career
Development Award Fellow, University of Liverpool, since 2007)
2005 until June 2009
Since 2005
Giulio Mafioletti (funded by CR-UK, now physiotherapist)
Bettina Meier (funded by CR-UK)
2006-2011
Rachael Rutkowski (funded by CR-UK and WT VIP award, now senior postoc WHEI,
Melbourne, Australia)
Remi Sonneville (shared with Julian Blow, funded by AICR and an EMBO long term
2006fellowship)
2006-2010
2007-2011
2009-2011
Pablo Ibanez (funded by the Parkinson’s Disease Society, now senior postoc ENS
Paris)
Ashley Craig (funded by a Wellcome Trust project grant, now free-lance editor,
proof-reader, Trivalent Editing, Tayside)
Aymeric Bailly (funded by CRUK and Wellcome Trust VIP award, now postoc, CNRS
Montpellier, France)
Invited Talks and oral presentation at meetings (since 2000)
Sept. 2001
Nov. 2001
Mar. 2003
May 2003
July 2003
Aug. 2003
Sept. 2003
Nov. 2003
Dec. 2003
Jan. 2004
Feb. 2004
Sept. 2004
Nov. 2004
June 2005
July 2005
Oct. 2005
Nov. 2005
Dec. 2005
Jan. 2006
Mar. 2006
April 2006
Jan. 2007
Feb. 2007
April. 2007
May 2007
EMBO cell cycle workshop, Salamanca, Spain
University of Vienna, Austria
University of Fribourg, Switzerland
Gordon Institute, Cambridge, UK
German Society for Cell Biology, Bonn, Germany
ISREC, Lausanne, Switzerland
University of Fribourg, Switzerland
Technical University of Braunschweig, Germany
Genetic Toxicology DNA repair meeting, Oxford, UK
ENS Lyon, France
University of Regensburg, Germany
EU meeting Brussels (Aging), EU
University of Hamburg, Germany
University if Oslo, Norway
University of Sheffield, UK
Institute for Aging Research, Innsbruck, Austria
EMBO workshop, Corsica, France
University of Zurich, Switzerland
University of Newcastle, UK
Plenary talk at International worm meeting (Los Angeles), USA
University of Turku, Finland
University if Helsinki, Finland
University of Milano, Italy
University of Aberdeen, UK
Apoptosis Meeting Obergurgl, Austria
European Apoptosis Meeting, Crete, Greece
Dundee/ Toulouse Meeting, Toulouse, France
Ninewells Hospital Dundee University, UK
University of Montreal, Canada
University of Toronto, Canada
MRC Edinburgh, UK
CR-UK Fellows Meeting, UK
p63 Workshop Rome, Italy
FMI Basel, Switzerland
ENS Lyon, France
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Nov. 2007
Feb. 2008
June 2008
Nov. 2008
Dec. 2008
Jan 2009
Mar. 2009
May 2009
June 2009
Aug. 2009
Oct. 2009
Nov. 2009
Jan. 2010
May 2010
Dec 2010
Feb 2011
Mar. 2011
May 2011
June 2011
Nov 2011
University of York, UK
Ninewells Hospital, Dundee, UK
MRC unit Sussex, UK
ENS Lyon, France
Sloan Kettering, New York, USA
Madison C. elegans topic meeting, USA
University of Helsinki, Finland
CR-UK Fellows Meeting, UK
IFROM, Milano Italy
Pasteur Institute, Paris, France
Apoptosis Meeting Obergurgl, Austria
University of Michigan Medical School, Ann Arbor, USA
Harvard Medical School, Boston, USA
University of Liverpool, UK
ENS Lyon, France
GENICA/CANGENIN Workshop in Athens, Greece
Association of Radiation Research, Meeting, Glasgow, UK
Plenary talk at International worm meeting (Los Angeles), USA
p63/p73 workshop, Toronto, Canada
Korean Cell Biology Meeting, Seoul, Korea
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences. Beijing,
China
The National Institute of Biological Sciences (NIBS), Beijing, China
Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Denmark
Institute for Genetics, Cologne, Germany
A*STAR meeting Singapore
ENS Lyon, France
Birmingham University
Invited talk, Embo Molecular Medicine Meeting Obergurgl (Given by post doc Rachael
Rutkowski), Austria
Dundee/ Belfast CRUK meeting
ENS Lyon, France
SPRING, Parkinson Disease Conference, Dundee
Cardiff University
Helsinki University
Talks of my group members (since 2005)
May 2006
Jan. 2007
May 2007
June 2007
April 2008
June 2008
Sept. 2008
Jan. 2009
May 2009
Aug. 2009
Feb 2010
Sebastian Greiss, European C. elegans Meeting, Hersonissos, Crete, Greece,
Bettina Meier, Genome Stability Network meeting, Cambridge, UK
Bettina Meier, CSHL, meeting Telomere Biology, Cold Spring Harbor, USA
Sebastian Greiss, International C. elegans Meeting, University of California at Los Angeles
Rachael Rutkowski, International Cell Death Society Symposium, Nice, France
Bettina Meier, European C. elegans meeting, Carmona, Spain
Sebastian Greiss, European C. elegans meeting, Carmona, Spain
Bettina Meier, BACR Conference Cellular Immortality: from Telomerase to Cancer Stem Cells,
Stratford-Upon-Avon, UK
Aymeric Bailly, Cancer and Control of Genomic Integrity, Copenhagen, Denmark
Rachael Rutkowski, EMBO Workshop on Model Organisms in Cell Death Research, Obergurgl,
Austria
Bettina Meier GENICA/CANGENIN Workshop in Athens, Greece
Ehsan Pourakemi, COST/CANGENIN meeting Stockholm
Aymeric Bailly, COST/CANGENIN meeting Stockholm
Pablo-Ibanez Parkinson’s Disease Society PI meeting London
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June 2010
Sept. 2010
Oct. 2010
Mar. 2011
Mar. 2011
July 2011
Sept 2011
Sept 2011
Ehsan Pourakemi, C. elegans topic meeting Heiderlberg, Germany
Bettina Meier, EMBO workshop Replication/repair & segregation of chromsomes, Freiburg,
Germany
Remi Sonneville, EMBO workshop Replication/repair & segregation of chromsomes, Freiburg,
Germany
Bettina Meier, EMBO conference, Telomeres and DNA repair, Marseille, France
Remi Sonneville, COST/CANGENIN meeting Milano
Rachael Rutkowski, EMBO molecular medicine workshop, Cell Death and Disease, Austria
Ehsan Pourakemi, EMBO molecular medicine workshop, Cell Death and Disease, Austria.
Neda Masudi, Los Angeles, International Worm Meeting, USA
Bettina Meier, COST/CANGENIN meeting Amsterdam
Joeg Weiss, COST/CANGENIN meeting Amsterdam
Poster prizes won by my group members
2006
2008
2009
2010
2011
Aymeric Bailly, School of Life Science, 2nd year PhD student presentations Dundee 2006
(2nd)
Sandra Moser, School of Life Science, 2nd year PhD student presentations Dundee 2006
(3rd)
Sebastian Greiss, School of Life Science, 2nd year PhD student presentations Dundee
2006 (4th)
Aymeric Bailly, The Biochemical Society, Annual meeting Cambridge 2008, UK, (1st)
Rachael Rutkowski, COST/CANGENIN meeting Stockholm
Ehsan Pourkaremi, best PhD student image award. Visions of discovery. Dundee
Ehsan Pourkaremi, GRE symposium, 1st poster award
Ehsan Pourkaremi, 2nd microscopy imaging award, Dundee
Ehsan Pourkaremi, 3rd poster prize, International C. elegans Meeting, Los Angeles
Collaborations within the Dundee CLS and the Medical School
Arno Alpi, Scills.
We collaborate on the GEN-1 Holliday junction Resolvase enzymes.
David Lilley, DNA Nucleic Acid Structure Research Group DNA.
We have a very fruitful collaboration on the biochemistry of GEN-1 Holliday junction Resolvase enzymes.
Dario Alessi, MRC Protein Phosphorylation Unit.
We share an interest in Parkinson’s Disease, and analyze C. elegans homologs of PINK-1 and LRRK2
protein kinases. Over the past years we built up a grouping of 5 students and Post Docs working on projects
related to Parkinson’s disease.
Dimitirs Xirodimas/ Ron Hay, Wellcome Trust Centre for Gene Regulation and Expression.
We have a common project on C. elegans ulp-3, which encodes the homolog of the NeddP1 deneddylation
protease. A deletion of this protease is defective in DNA damage induced apoptosis.
Gyorgy Hutvagner, Wellcome Trust Centre for Gene Regulation and Expression.
Gyorgy is helping us with the biochemistry of C. elegans GLD-1. We also generated C. elegans GFP reporter
strains to genetically screen for new micro RNA regulators. These reporter constructs work very well and we
hope to convince a Wellcome Trust Centre PhD student to return to our labs after his rotations to follow up on
this.
John Rouse, MRC Protein Phosphorylation Unit.
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We have neighbouring labs and have joint lab outings approximately every 6 months. At the moment we
contribute to one of John’s projects by analyzing the C. elegans homolog of a conserved gene needed for
DNA cross link repair.
Julian Blow, Wellcome Trust Centre for Gene Regulation and Expression.
We have a joint Postdoc, Remi Sonneville focused on characterizing key C. elegans DNA replication genes
and their differential regulation during embryonic, late larval and germ line cell cycles. Furthermore, Remi
uses functional genomic approaches to identify new DNA replication genes..
Sarah Couthurst, Molecular and Environmental Microbiology.
We will interact with Sarah, who is a new Principle Investigator in MEM helping her to use C. elegans as a
virulence model for Serratia marcescens infections.
Steve Keyse, Biomedical Research Institute.
Steve supports us with his biochemical know-how to study the biochemistry of the C. elegans LIP-1 MAP
kinase phosphatase.
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