CELL BOUNDARIES The Cell Membrane and Transport Processes I. The Structure and Function of the Cell Membrane Components of the cell membrane: Phospholipid bilayer – nonpolar fatty acid tails turn inside, polar phosphate groups turn outside – forms a flexible structure as a boundary Integral proteins – act as ion channels or molecular channels also help in cell identification Peripheral proteins – act as receptors Carbohydrates – Identification tags outside of the cell membrane (glycolipids and glycoproteins) Cholesterol – helps stabilizing the membrane by making it more solid The Function of the Cell Membrane Surrounds the cell. Regulate the transport of molecules in and out of the cell -semipermeable Immune response Attaches the cells to other cells or surfaces. The model that describes cell membrane, the Fluid Mosaic Model http://www.youtube.com/watch?v=ULR79TiUj80 http://www.youtube.com/watch?v=GW0lqf4Fqpg Selective Permeability Cell membranes control what goes in and out of the cell It allows some substances to cross more easily than others Cell membrane is amazingly thin II. Passive Transport Processes Transport means the movement of molecules from one side of the cell membrane to the other Transport is influenced by: The The The The size of substances polarity of substances concentration of substances permeability of the cell membrane Passive transport: requires no energy from the cell, the energy comes from the difference in concentration not ATP. Moves smaller substances from the higher to the lower concentration area. Important in transporting O2, CO2, water, ions, small molecules. http://bcs.whfreeman.com/thelifewire/content/chp05/0502001.html Types of Passive Transport Diffusion:The principal method of moving substances within the cell and small molecules across the cell membrane. http://www.stolaf.edu/people/giannini/flashani mat/transport/osmosis.swf Osmosis: the diffusion of water across the cell membrane. Especially important when the solute cannot move through the membrane. Tonicity: Describes the tendency of a cell in a given solution to lose or gain water. Isotonic, hypertonic, and hypotonic Osmosis in action Isotonic solutions – when cells are put into solutions that have equivalent salt concentration, visible osmosis does not take place. Hypotonic solutions – Cells in very dilute solutions will take in water and eventually can burst (animal cells). Hypertonic solutions – Cells in very concentrated solutions will lose water and shrink. http://bcs.whfreeman.com/thelifewire/cont ent/chp05/0502001.html Facilitated Diffusion – a special type of diffusion in which the transported molecules are moved by a the help of a transport protein. III. Active Transport http://bcs.whfreeman.com/thelifewire/content/chp05/0502002.html Transport processes that can move substances from the lower concentration area to the higher by using energy. Energy is gained by using ATP molecules. A type of active transport is the NaK ion pump 3 sodium ions move out of the cell with the help of a transport protein, while 2 potassium ions move into the cell. This process requires energy in the form of ATP. IV. Transport of Large Particles Endocytosis – a process by which large particles can move into the cell by using membrane vesicles Types of endocytosis: Phagocytosis – engulfing solid particles Pinocytosis – engulfing liquids, solutions Receptor-mediated endocytosis – moving into the cell by first binding with receptor molecules on the cell’s surface. http://bcs.whfreeman.com/thelifewire8e/content/cat_0 10/0504003.html Exocytosis – the process by which the cell releases large molecules through its cell membrane