Happy Tuesday Bellwork: Draw and identify the structure below. Label it’s three parts Happy Tuesday Bellwork: Draw and identify the structure below. Label it’s three parts The sugar and phosphate part of the nucleotides form the DNA backbone. What are the two enzymes used in the replication process? What are the two enzymes used in the replication process? Helicase – performs what function? DNA Polymerase – performs what function? What is the substrate for each enzyme? Remember…enzymes only work on ONE substrate! •each half of the DNA double helix has everything it needs to recreate the other half •the two strands are complementary •complementary = something that completes something else If you only have half of a DNA double helix, how can you fill in the other half? •Semi-conservative: each replicated DNA molecule is made of one original strand and one new (complementary) strand The complementary strand for AGGCTAAGTCGGTA is The complementary strand for AGGCTAAGTCGGTA is TCCGATTCAGCCAT… Your turn… Write the complementary strand for the following sequence: CGGAATTCG GCCTTAAGC How does the structure of DNA make it easy to replicate? DNA Replication Foldable 1. Fold the edges of your paper toward the BACK along the dotted lines. 2. Now fold the two sides in to meet in the middle (also marked with a dotted line). 3. Using the given ORIGINAL strand, complete the complementary strand. 4. Open your edges. Now “replicate” the DNA by filling in the two new strands. 5. Put your name on your paper and turn it in! I will keep them until next week, when we will add another step. DNA is the “molecule of life” • Sheet protectors at your table. • Choose one organism and create the complimentary strand. • DNA worksheet.