Organic Chemistry = The study of compounds that contain bonds between carbon atoms The Chemistry of Carbon Carbon has the ability to bond with many other elements….. SPONCH CaFe Sulfur Phosphorous Oxygen Nitrogen Carbon Hydrogen Calcium Iron Carbon has 4 valence electrons Therefore it can makes four bonds Carbon atoms can form many types of bonds…. Macromolecules Macromolecules (macro = large) are very large molecules Composed of smaller units called monomers (mono = one) which join together to form polymers (poly = many) The process of monomers joining together to form polymers is called polymerization Four groups of organic compounds found in living things Carbohydrates Living things use carbohydrates as their main source of Breaking down sugars supplies immediate energy for all cell activities Carbohydrates Made up of carbon, hydrogen and oxygen atoms Carbohydrates Monomers = monosaccharides Ex) Glucose Polymers = Polysaccharides Ex) Starch, Cellulose The process of monomers joining together to form polymers is called polymerization Lipids • Lipids are fats! – Cholesterol – Oils – Steroids – Waxes Lipids (Fats) - Function in energy storage - Key component of cell membranes Lipids Contain carbon, oxygen and hydrogen atoms Some may also contain nitrogen and phosphorous …. That’s most of our SPONCH CaFe! Lipids are typically made up of: A Glycerol molecule + Fatty Acid Chains Two types of lipids are: - Triglycerides - Phospholipids Triglyercide (tri = 3) Structure: • A glycerol backbone • Three fatty acid chains Why are triglycerides important? Triglycerides are used by the body to store energy! For example: When you eat a big meal, your body uses some of the energy, but also stores some of it Triglycerides can be broken down and used for energy when your body needs it (I’m hungry!) Phospholipid: - Contains a phosphate group - Glycerol molecule - Two fatty acid chains Phospholipids are made up of two groups: Polar Group - interacts with water Nonpolar Group - does not interact with water “-phillic” = attraction, love “water loving” “-phobic” = fear, repelled by “water fearing” Arrangement: • Hydrophilic heads near/touching water • Hydrophobic tails away from water The two rows of phospholipids which make up a cell membrane is called the lipid bilayer (bi = two) So in a cell, the membrane is made of phospholipids: Lipids may be saturated or unsaturated Saturated - Only single bonds between carbon and hydrogen atoms - Chains are straight Unsaturated - One double bond between two carbon atoms - Chains are bent Saturated or unsaturated? Saturated or unsaturated? Nucleic Acids Nucleic Acids • Contain genetic material – Contained in the nucleus • Every living thing has genetic material • Nucleic acids are made up of: – Hydrogen – Oxygen – Nitrogen – Carbon – Phosphorous Nucleic Acids The monomers of nucleic acids are nucleotides Molecular Structure of a Nucleotide Nucleotides bond together to form polymers Nucleic Acids May be DNA or RNA • Ribonucleic Acid (RNA) • Deoxyribonucleic Acid (DNA) Do Now: What is the function of nucleic acids? What are the two types? How are they different? What is a monomer called? Proteins Why are Proteins Important? • Regulate the rate of chemical reactions – Example: Lactose breakdown • Main components of muscles and bones • Transport in cells Molecular Makeup • Proteins contain the following elements: – Carbon – Oxygen – Hydrogen – Nitrogen – Sulfur (small amounts, but very important) The monomers of proteins are called amino acids Amino acids bond together to form polypeptides The bonds between the amino acids are called peptide bonds A polypeptide: Protein Folding Proteins must be folded in order to become functional • Proteins may become unfolded when they are exposed to extreme environments • This is called denaturation and leaves the protein non-functional • Example) High fevers can be very dangerous! Yikes! Denaturation Mad Cow Disease • Degenerative neurological (brain) disorder • Can be passed on to humans through contact with infected meat or animal tissues • The result of an incorrectly folded protein – Can then cause other proteins to fold incorrectly Chemical Reactions A chemical reaction is a process that changes one set of chemicals into another set of chemicals Reactants are the elements or compounds that enter into a chemical reaction The elements or compounds produced by a chemical reaction are known as products CO₂ +H₂O H₂CO₃ (carbonic acid) What are the reactants? What are the products? H₂CO₃ (carbonic acid) CO₂ +H₂O What are the reactants? What are the products? Essentially, chemical reactions involve the breaking of bonds in reactants and the formation of new bonds in products Demo Do Now! Identify the reactants and products in the chemical equation for photosynthesis (the process by which plants use carbon dioxide, water and sunlight to produce glucose and oxygen) Photosynthesis Chemical Reaction Activities • Water bottle and balloon experiment • Hand warmer experiment Amylase Enzymes Proteins that act as catalysts for chemical reactions Catalyze means to speed up the rate of a chemical reaction So, enzymes speed up chemical reactions in cells Activation Energy The energy needed to get the reaction started Enzymes lower the activation energy How do enzymes do this? The substrate is the reactant in the chemical reaction The active site is the region of the enzyme that the substrate binds to Lactose Intolerance • Dairy contains a protein called lactose • Lactose intolerant people can’t break this protein down Lactose pills can help! Enzymes are highly specific molecules!! Ex) Pepsin breaks down protein in the stomach Enzymes function best at certain conditions • Temperature (too high or low = bad) • pH (too acidic or too basic = bad) These conditions are considered optimal for enzyme activity Enzyme Comic Design a comic that shows the function of enzymes