Aim: How does DNA Replicate? 1) Fill in the matching bases: • G• T• A• C• C• T- • 2) Explain why DNA replication has to happen before mitosis can occur? Replication video clip • http://www.dnatube.com/video/365/DNAReplication Go over Replication Questions DNA replication: making an identical copy of a cell’s DNA. During DNA replication, the double strand of DNA unzips, as weak H bonds between the base pairs are broken. Complete the DNA Replication Worksheet DNA • The chemical molecule that makes up chromosomes. • http://www.brainpop.com /science/cellularlifeandg enetics/dna/ Aim: How can we describe the structure of DNA? • • • • 1) What is a nucleotide? 2) What are the three parts of a nucleotide? 3) What is the shape of DNA called? 4) What 2 things make up the SIDES of the molecule? • 5) What 4 things make up the STEPS of the molecule? Aim: How does the structure of DNA relate to its function? Do Now: • Color-Code “The Double Helix” Sheet • Pick a different color for A C G and T • Color P Black or Grey • Leave D White Do Now Review • What do the letters C, N, and H, O, and P represent? • What are the lines between the letters? Homework Review • Go over Homework Matching DNA Base Pairs Fill in the “complementary” base pairs. • C• A• G• T • C• C• A- What does DNA do? • What happens when it doesn’t work? • What do you think happens when it DOES work? Aim: How can we model DNA replication? In-class lab You will need: • Paper • Scissors • Glue/Tape • The Lab Sheet Step 1 • Cut out the 6 nucleotides from the top of the sheet only. Arrange them on the blank sheet of paper, matching the nucleotides. Your DNA should have 2 sides. Show your teacher. Step 2 Cut out the 4 nucleotides from the bottom of the sheet. Arrange them on the blank sheet under your first diagram. Steps 3 and 4 • Fill in the base pairs for the replicating DNA • 1) Why is it important for DNA to replicate? • 2) Why does A pair only with T? Aim: How can we describe the structure of proteins? Do Now • 1) How do the new strands of DNA compare to the original strand after replication? • 2) What is the result of DNA replication? Motivation • Use the letters e, a, r, and d to make as many words as you can. • Letters are used to make . • DNA is used to make . • How did DNA determine your trait of skin color? Protein Model • How would you describe this model? Amino Acids • Amino Acids are the “building blocks” of proteins. • There are 20 kinds. Proteins • Made of Chains of Amino Acids. • A polypeptide is a simple protein chain. • Functions: enzymes, pigments, antibodies, parts of cells and tissues. • How does one protein differ from another? Aim: How do genes make proteins? Do Now: • Complete the Learning Log using your notes from last lesson. Motivation • Morse code had dots and dashes. What about DNA? Fill out the complementary base pairs • Gene #1 • Gene #2 Cell Diagram – Where are proteins made? How do we go from DNA code to protein? DNA vs. RNA Genes • A gene is a segment of DNA that codes for a protein. • Cells put proteins together one at a time.