Chapter 3: Cells Introduction An adult human body consists of about ______________________________________ cells. There are at least_______________________________________________ varieties of cells. Cells differentiate considerably in _________, ________________, and _________________. Cells have different, distinctive shapes that make possible their______________________. History Late 1600’s, _______________________ was looking through a primitive microscope at some _______________________. Saw ______________________that reminded him of _________________________ so he named the structure cells. Overview of the Cellular Basis of Life (1) Cells are made up of _____ elements primarily: ______________________________________ Make up most of ___________________________ The other elements are important for cell functions: _________________________- blood clotting and other things. __________________- necessary to make ________________________(carries oxygen in the blood). _____________________ is required to make the __________________ that controls metabolism. _______________________________________ - carry electrical impulse. Electrolytes. ________________________________________ essential for transmission of nerve impulses and muscle contractions. Overview of the Cellular Basis of Life (2) Cells are about ___________________________________. __________________________- all the cells of the body are constantly bathed in a dilute saltwater solution. Comes from the _________________________. All exchanges between _____________________________are made through this fluid. Cell size: 2micrometers (_________________) to over 1 meter (___________________) Long cells are ______________________________________________ Cell structure reflects the job. _____________________________- red blood cells _______________________________- nerves _____________________________- smooth muscle cells _________________________- epithelial cells ______________________ - wander freely through the body tissue. And protect the body by ____________________________ and other foreign substances. Anatomy of a Composite (Generalized) Cell All cells have three main regions: __________________________________________________ Nucleus- ________________________________________________________________ Cytoplasm- ______________________________________________________________ Plasma membrane- _______________________________________________________ Nucleus DNA- contains the blueprint that contains all the instructions needed for building the whole body ________________________ for building proteins. If a cell ejects its nucleus it ____________________________________________ Nucleus usually forms to the ________________________________________________ Nucleus has three distinct regions: _______________________________________ _______________________________________ _______________________________________ Nuclear Envelope _______________________________________________ Between the two layers is _______________________________________. At various points the two layers of the nuclear envelope approach each other and fuse_________________________________________ ___________________________________ but much freer than else where because of large pores. Encloses a jellylike fluid called ______________________ in which _______________________________are suspended. Nucleoli ___________________________________________________________________________ _________________________________ are assembled here Then the __________________________________________________________________. Ribosomes do ____________________________________________. Chromatin __________________________________________________________ When a cell is dividing to form two _________________________ the __________________ threads coil and condense to form dense, rod-like bodies called ________________________ Plasma Membrane (1) ____________________________________________________________________________ them from the surrounding environment. Consists of ___________________________ arranged ______________________ in which protein molecules float. Most of the lipid portion is __________________________. With a substantial amount of____________________________. The heads are __________________________________________ The tails are _____________________________. These tails make the cell relatively impermeable to most ______________________________ molecules. Plasma Membrane (2) Some proteins are______________________ Many proteins mounted on the cell exterior are ___________________________________________________________________________ Most proteins are for __________________________________________________________are a sugar protein. The cell surface is fuzzy, sticky area. o Determine your ___________________________ o Changes in glycoproteins occur in cells that are ______________________________ Specializations of the Plasma Membrane (1) ___________________________- tiny fingerlike projections that greatly increase the cell’s surface area for absorption so that the process occurs more quickly. __________________________________- vary structurally depending on their roles. ________________________________- impermeable junctions that bind cells together into leak-proof sheets that prevent substances from passing through the extracellular space between cells o __________________________________________________________________ Specializations of the Plasma Membrane (2) Membrane junctions ___________________________- anchoring junctions that prevent cells subjected to mechanical stress (____________________) from being pulled apart. _________________________- commonly seen in the heart and between ______________________, function mainly to allow communication. o ___________________- connected to neighboring cells. Cytoplasm ___________________________________________________________________________ Site of most ______________________________________________________________ 3 major elements: _________________________________________________________________ _____________________ is semitransparent fluid that suspends the other elements. _____________________ are the metabolic machinery of the cell. _____________________ are not functioning units but are chemical substances that may or may not be present o _____________________________________________________________________ _____________________________________________________________________ Cytoplasmic Organelles _______________________________- sausage-shaped organelles Squirm, lengthen and _________________________________________________________ Outer membrane ____________________________________________________________. Carry out reactions in which ___________________________________________________. Captured and used to form ________________________________________ _____________________________ of the cell _____________________________have lots of mitochondria __________________________ has few mitochondria _____________________- tiny round, dark bodies made of proteins and one variety of RNA called ribosomal RNA. _________________________________________ __________________________________________. _______________________________________has ribosomes attached to it. ______________________________- is a system of fluid-filled cisterns that coil and twist through the cytoplasm. __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ ____________________________________. Does not do protein synthesis. It does cholesterol synthesis and breakdown (fat and detoxification of drugs) found in the liver and testes _______________________________- appears as a stack of flattened membranous sacs, associated with swarms of tiny vesicles. _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ o ___________________________________________ are packaged this way. ___________________________- breaks down bodies, appear in different sizes and are membrane bags containing powerful digestive enzymes. Eat ___________________________________________________that enter the cell. _____________________________________________________ _____________________________________________________ Homeostatic Imbalance: ___________________________________________________________________________ ___________________________________________________________________________ ___________________________- membranous sacs containing powerful oxidase enzymes that use molecular oxygen (O2) to detoxify a number of harmful or poisonous substances (alcohol and formaldehyde) ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ __________________________________________________________________________ ___________________________________________________________________________ _________________________________- elaborate network of protein structures extends throughout the cytoplasm. _________________________________________________________________________ _________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ________________________________- cell motility and in producing changes in cell shape ________________________________- tube-like, distribution of organelles and are very important during cell division ______________________________- paired lie close to the nucleus __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ Other Organelles __________________________________________________________________________ __________________________________________________________________________ Cell Physiology Membrane Transport ______________________- homogeneous mixture of 2 or more components. _______________________- dissolving medium (body has water) _______________________- substances that are present in smaller amounts. _______________________- solution containing small amounts of gases (oxygen and carbon dioxide) nutrients, and salts, dissolved in water. _______________________- continuously bathes the exterior of our cells _______________________- means that a barrier allows some substances to pass through it while excluding others. Passive Transport Processes: Diffusion and Filtration _________________________________- the process by which molecules tend to scatter themselves throughout the available space. The speed of diffusion is affected by the size of the molecules __________________________________________________________________________ Molecules move passively through the membrane if: o _____________________________________________________________________ o _____________________________________________________________________ ____________________________- unassisted diffusion of solutes through the plasma membrane. o _____________________________________________________________________ ____________________________- diffusion of water through a selectively permeable membrane _____________________________- means for certain needed substances (glucose) to enter the cell. Filtration _________________________________________________________________________________ ___________________________________________________________________________ ___________________________________________ ___________________________________________ Active Transport Processes ___________________________________- similar to facilitated diffusion _________________________________________________________________________ _________________________________________________________________________ _________________________________________________________________________ __________________________________________________________________________ Bulk Transport ____________________________- out of the cell o _________________________________________________________________ o __________________________________________________________________ ________________________________- into the cell o ________________________________________________ o ________________________________________________ o _________________________________- the cell forms a tiny pit and then its edges fuse around the droplet of extracellular fluid unlike phagocytes this is routine activity for a cell. Cell Division 2 major periods: __________________________________________________________________ Interphase is really metabolic phase not resting phase. Events of cell division: o Mitosis: _______________________________________________________(happens when mitosis is nearly completed) Cytokinesis Occurs during late _________________________________________________________________ At the end _____________________________________________________ Genetically identical to the_____________________________________ Carry out ___________________________________________________________________ Sometimes the cytoplasm does not divide this _____________________________________ o Fairly ________________________________________________ Mitosis gone wild is the basis for _____________________________________________________ Metabolism and T3 and T4 hormones The sum total of the chemical reactions that occur in the body _________________________________________ that are required for normal development of brain tissue. Also normal metabolism of the body. ___________________________________________________ Can also cause _____________________________________ Too much leads to _______________________________________ ______________________________________________________