Unit 1: Cells Essential Questions What makes something “alive”? What are cells and what do they do? How are organisms organized? How do substances move in and out of cells, and how are they transported to the rest of our body? What are enzymes and how do they help our body function? How are organic molecules used in our body? Day 1 Required Readings: Section 2.1: Cells and cell structures Learning Objectives: The basic unit of living organisms is the cell All cells have certain features in common, but there are differences between plant and animal cells The study of cells requires the use of a microscope Vocabulary Organelle Cell membrane Cell wall Nucleus Vacuole Mitochondria Chloroplast Cytoplasm Prokaryote Eukaryote Video: Cells Song Starter There are some microscopes set up with different cells at the back. In your group, go to each station and observe the different slides. I will tell you when time is up and to switch to the next station. Write down what you observe on the different slides. Be sure to label them. When back in your seats, discuss with your group the similarities and differences between the slides. Time: 15 minutes Activity One: What is a Cell? Observe the dish that has been placed on your desk. Is it a living being? Why or why not? What makes something a living thing? Brainstorm with your group features/characteristics that are common to all living things. What is a cell? What features/functions does a cell have? Time: 15 minutes Activity Two: What are the different types of cells? Look at the pictures provided and point out any similarities and differences between the three types of cells. What structures can you see? Time: 15 minutes Activity Three: Prokaryote vs. Eukaryote The pictures you were just looking at were examples of prokaryotic cells and eukaryotic cells. What do these words mean? Create a table to distinguish the difference between prokaryotic and eukaryotic cells Time: 15 minutes Activity Four: Plant Cells vs. Animal Cells Create two different slides: One of an onion cell One of a cheek cell Draw what you see in both of them Use the following pictures to help you with the following questions Compare and contrast the two different types of cells What features do they have in common? What features are different. Time: 30 minutes Animal and Plant Cells Homework: Complete the “Cell as a City” Read section 2.2 Day 2: Organization of Living Things Required reading: Section 2.2 Learning Objectives: To understand that the body of a living organism is a highly organized structure To understand that cells, tissues, organs and systems represent increasing degrees of organization in living organisms The structure of cells relate to its function; cells are specialized Vocabulary Specialized cells Structure and function Levels of organization Organelle Cell Tissue Organ Organ system Organism Starter Draw a pyramid and place these words in the pyramid from smallest (bottom) to largest (top) Cell Organism Organ Molecule Tissue Atom Organ system Time: 10 minutes Video: The Organization of Multicellular Organisms Activity One: Review Cell Organelles Get in a group with 2-3 other people who you do not sit with Compare your answers from the “Cell as a City” and labeling homework. Discuss any discrepancies between your answers and try to come up with answers together for any you left blank. Do not copy answers Time: 20 minutes Activity Two: How are organisms organized? You have put the levels of organization in order from smallest to largest, but what does each one mean? In your group, come up with an explanation for each term using an example: Organelle, cell, tissue, organ, organ system, organism You can represent your information in any way you like Time: 20 minutes Activity Three: Use your text book and microscope slides at the back to help you determine why different cells are shaped differently (cell specialization) Describe how the structure (how it looks) of the following cells relates to its function (what it does) Red blood cell Nerve cell Muscle cell Root hair cell Xylem vessel Time: 30 minutes Closing Activity Explain the following situations: Why do muscle cells have more mitochondria than other types of cells? Why do leaves in plants contain a lot of chloroplasts? Where would you find a lot of ciliated cells? Why? Time: 10 minutes Homework Read Section 2.3 Day 3: Movement in and out of Cells Required Reading 2.3 Movement in and Out of Cells Learning Objectives: To understand that the contents of a living cell must be kept separate from its surroundings To know that the cell surface membrane can act as a barrier to some substances which might pass between a cell and its surroundings To understand the principles of diffusion, osmosis, active transport and phagocytosis Vocabulary Equilibrium Diffusion Osmosis Hypertonic Hypotonic Isotonic Passive transport Active transport Video: Diffusion and Active Transport Starter Give an example of diffusion or osmosis. Is this system in equilibrium? Why or why not? If it is not in equilibrium, draw how it would look in equilibrium. Time: 10 minutes Cell Project Due September 13 Word file is on wiki Work with a partner Activity One: Observing Diffusion Observe the beaker that has been placed on your desk Describe what you see Write down any questions that you have about what is happening Discuss in your group what is happening and why using the following terms: Diffusion Concentration gradient Movement of particles Time: 10 minutes Activity Two: The structure of the cell membrane Cell membranes are often described as a “fluid mosaic” What does this mean to you? Why do you think this would be used to describe the cell membrane? Create a model of the cell membrane using the play-doh Be sure to include: Phospholipid bilayer Membrane proteins for transport Time: 20 minutes Activity Three: osmosis is the diffusion of water particles Osmosis is a special type of diffusion involving water particles We will model this by putting decalcified eggs (the “cell”) into water and sugar solutions to observe the net movement of water particles Design an experiment with your lab group Use the rubric to be sure you have all the necessary included sections Show me when completed and set up your practical Time: 35 minutes Closing Draw a picture of an animal cell and a plant cell Show what happens when the cells are placed in a hypertonic, hypotonic and isotonic solution Homework We will continue with section 2.3 next lesson Day 4: Movement in and Out of Cells (Cont’d) (60 minutes) Required Reading 2.3 Movement in and Out of Cells Learning Objectives: To understand that the contents of a living cell must be kept separate from its surroundings To know that the cell surface membrane can act as a barrier to some substances which might pass between a cell and its surroundings To understand the principles of diffusion, osmosis, active transport and phagocytosis Starter What is the difference between active and passive transport? Use a picture to explain how active transport is achieved Give an example of active transport in the body Time: 10 minutes Activity One: Results from egg lab Obtain the masses from your eggs and record your results CERR lab report due September 3 Extension activity (include at the end of report): Bodies of water have different salinities (salt concentrations) Time: 20 minutes Activity Two: Observing Osmosis and Diffusion We will be completing the “Examining Cellular Transport” lab activity Read over the instructions with your lab group Set up your materials and begin the practical Time: 25 minutes Closing Which of these statements match your results and the observations you have had about cellular transport? Water molecules move across a barrier to reach equilibrium. Sugar molecules move across a barrier to reach equilibrium. Cells in a hypotonic solution shrink. Cells in a hypotonic solution expand. The difference between active and passive transport is passive transport requires energy in the form of ATP. Closing The results obtained didn’t turn out as planned, so here is the data your group can use Time (min) Solution Level in Pipette (mL) Initial 0.85 1 0.81 2 0.78 3 0.77 4 0.75 5 0.74 6 0.73 7 0.71 8 0.70 9 0.70 10 0.69 Total Change in Solution Level (mL) Homework Complete the Examining Cellular Transport lab packet – due September 5 Egg lab – due September 3 Read Section 3.4 Day 5: Enzymes Control Biochemical Reactions Required Readings: 2.4 Learning Objectives: To appreciate that biochemical reactions in living organisms must be controlled To understand how enzymes can act as biological catalysts To list and explain factors that affect enzyme activity To list some examples of human exploitation of enzymes Vocabulary Enzyme Catalyst Substrate Product Denature Activator Inhibitor Starter Starter Chew on the crackers provided Don’t swallow them until instructed to do so What did you notice about how the taste changed when you were chewing? What is happening here? Time: 15 minutes Activity One: Enzymes are biological catalysts Activity One (cont’d) Discuss the following questions with your group: What is an enzyme? How do they work? What conditions do they work best in? (Hint: Think about pH, temperature, concentration etc.) Where do we find enzymes? What are some examples of enzymes? How can we identify if something is an enzyme (Hint: Think of how they are named) Time: 20 minutes Activity Two: Creating an enzyme Using the play-doh create a step-by-step model of how an enzyme works Include the following: Enzyme with active site Substrate Enzyme-substrate complex Product Draw the steps on your cue cards Time: 25 minutes Activity Three: How does an enzyme work? In your group, use the large paper to create a graph that represents the rate of a reaction in our body and how enzymes work to make them faster On your graph, include how temperature and pH can also affect the enzyme activity and how they play a role in the reaction rate Time: 25 minutes Closing Create an acronym for the word ENZYME (you’ll have to be creative with the “Z”!!) Homework Read Section 2.5 Work on Egg Lab (CERR model) – due September 3 Work on Cellular Transport Questions – due September 5 Day 6 Required Readings: 2.5: Humans use enzymes from microorganisms Answer questions posted on Wiki Learning Objectives: To understand that enzymes have many roles which benefit humans To know examples of range of uses of enzymes To understand the benefits of enzyme immobilization Vocabulary Pharmaceuticals Textiles Starter Enzymes are used to benefit our daily lives. Write down questions that you would pose to the class about enzymes and their use in real life and industry to pose to the class (i.e. pretend you are the teacher asking the students questions). Time: 15 minutes Activity One: Using Enzymes You are going to be researching some different ways that people use enzymes from microorganisms to benefit our every day lives You will choose how you would like to present your data. You will then conduct your research and present your findings. Write a story, song or poem Create a documentary Make a powerpoint Create a table and/or graph presenting the data you collected Time: 30 minutes for research Activity One (cont’d) The following items must be included in your presentation: How are enzymes used in pharmaceutical production? How are enzymes used for biological washing powders? How are enzymes used in food production? How are enzymes used in textile production? Time: 30 minutes Activity Two: Making your presentation After you have collected the information you need, work in your group to make up your presentation There are 2 computers that can be used. Time: 30 minutes Activity Three: Presenting your findings Present to the class your findings Time: 15 minutes Closing What was the most interesting thing that you learned about enzymes today? Write down your point and hand it to me before you leave. Homework Read section 2.6 We will be testing an enzyme’s efficiency next lesson The enzyme we will use is catalase What does catalase do? Think of ways that you can test an enzyme to see where it is most efficient Day 7: Enzyme experiments and the scientific method Required readings: 2.6: Enzyme experiments and the scientific method Learning objectives: To understand how enzymes can work as biological catalysts To understand and apply the scientific method Vocabulary Scientific method Independent variable Dependent variable Control Starter In this lab, we will be using the enzyme catalase (from potatoes) to break down hydrogen peroxide (H2O2) Write a balanced chemical equation for the break down of hydrogen peroxide What are the different variables we could test in this lab? Your text mentions one way. Come up with at least 2 more ideas. Time: 10 minutes Activity One: Planning for the experiment For this lab, you can choose the variable you wish to test: pH Temperature [Catalase] We will time how long it takes for a disc soaked in the catalase to float to the top of the hydrogen peroxide solution Time: 15 minutes Activity 1 (cont’d) Create a plan to test how long it will take for the discs soaked in catalase to float to the top of a beaker with hydrogen peroxide Refer to the rubric for what to include Time: 15 minutes Activity Two: Recording your results Create a table to record your results in Data to be collected (Temperature, pH, [Catalase] Time taken for discs to float (do 3 for each condition) Rate (floats/second) Activity Three: Performing the experiment When your group is ready, show me your plan Go to the back and complete the practical Clean up when you are finished Time: 45 minutes Closing Sit with someone who is not in your lab group and also someone who you have not worked with this year and discuss your results What did you see? Did everything go as expected? Homework You will complete a CERR model lab report for this lab – due September 11 Read Section 2.7 Day 8: All living things are made up of organic molecules Required Readings: 2.7 Learning Objectives: To understand that the structures of living things depend on the molecules that make them up To list the types of molecules found in living organisms Vocabulary Organic Carbohydrate Lipid Protein Nucleic acid Monomer Polymer Starter Do you agree or disagree with the following statements? If you disagree with the statement, correct it. All organic molecules contain C, H, O, and N Starch is a polysaccharide Lipids are made of a glycerol molecule and fatty acid chains There are 15 different amino acids A polymer is many molecules attached to each other Nucleic acids are made of a nitrogenous base, a sugar and a hydroxyl group Time: 15 minutes Activity One In your group, create a poster that shows the four different groups of organic compounds. Include: What are they made of (monomer or subunit)? How are the macromolecules formed? What are they used for? 2 food sources (where applicable) Time: 30 minutes Video: Macromolecule Rap Activity Two (cont’d) Create your own rap for the 4 macromolecules Include: What they are made of How they are formed What they are used for in our body Time: 30 minutes Closing Which of the four macromolecules do you think is the most important for our bodies? Write a few sentences to support your point of view. Share your ideas with your group members when you are finished. Time: 10 minutes Homework Read Section 2.9 Enzyme lab (September 11) Cell model project (September 13) Unit 1 test (September 13) Finish posters and rap (September 11) Day 9: Testing for Biochemicals Required Readings: 2.8 Questions for September 12 from wiki Learning Objectives: To describe simple chemical tests for the molecules of living organisms To test different foods to see what macromolecules are in them Vocabulary Emulsion Starter Complete the table Time: 15 minutes Macromolecule Lipid (fat) Protein Starch Glucose Test Positive Result Activity One You will be testing different substances to see what organic molecules are present The following substances will be tested: Vegetable oil, potato, egg, bread, table sugar, canned pineapple, beans, meat Create a table for your data Time: 10 minutes Activity Two Perform the tests for the food samples provided Record your data in the table Clean up when you are finished Time: 30 minutes Closing What foods were high in: Carbohydrate Lipid Protein What implications does this have for our diet? How does the food we ingest affect the macromolecules that are needed in our body? Time: 15 minutes Homework Test: September 13 Sections 2.1-2.8 Review for 30 minutes, test will take 1 hour You may bring your text book to the test