Lecture 2 Class Activities
Overview of Unit 1: The dynamic cell
Structure of the Plasma Membrane
Each membrane phospholipid:
A. always has ____
B. is composed of ___
C. has a head and ____
D. is attached to a ___
E. has two ______
Fluidity of the Plasma Membrane
If cells that normally grow at 37oC are cooled to 32oC, what change would allow the white blood
cell to maintain the same membrane fluidity in the new environment?
A. Add more ______
B. Add more phospholipids with _____
Application: Licofelone treats colon cancer
Receptor name:
Ligand name:
Reference: http://www.ncbi.nlm.nih.gov/pubmed/22343320
A new drug to treat colon cancer, called Licofelone, acts by preventing a receptor tyrosine
kinase on the plasma membrane from forming dimers (pairs). Which of the following would
most likely produce this result?
A. Increasing _____
B. Increasing membrane _____
C. Increasing membrane _____
For Online Discussion:
Two types of cancer cells (A and B) found in the pancreas differ in the
total concentration of phospholipids in their membranes that are
unsaturated (see graph). Which of the following statements is most
likely to be TRUE?
A. Cell type A has more phospholipids tails with ___
B. Cell type B has tyrosine kinase receptors that ____
C. Cell type A shows evidence of less ____
D. Cell type B will move _____