Complex Patterns of Inheritance Ch 11 Summary Exceptions to Mendelian Genetics • Polygenic • Incomplete Dominance • Co-Dominance • Multiple Alleles • Pleiotropy • Gene linkage • Sex-linked Traits OTHER Extension: • Karyotype • Pedigrees – Patterns of inheritance – Inferring genotype • Non-disjunction - trisomy Where is this happening again? Poly-genic Traits Complete Dominance Different? Multiple Alleles glycoproteins = antigens Uni Uni Compare and Contrast Pleiotropy: Cystic fibrosis is a good of example of pleiotropy, where a mutation in a single gene affects multiple systems in this case the lungs, pancreas, and sweat glands BIO SmartStarter – 11/20/15 Xb - Color Blind XB – not Color Blind 1. Make a Punnett square for the cross illustrated here. 2. What are the genotypic and phenotypic ratios (probabilities) for the offspring?