WHY DO CELLS DIVIDE? The larger a cell becomes the harder it is to move enough nutrients and waste across the cell membrane As the cell grows and get bigger and bigger the DNA can no longer meet the needs of the bigger cell. CELLS DIVIDE BEFORE THEY BECOME TOO BIG. The cell will divide forming two identical daughter cells. Before the cell divides the DNA is replicated so there is an exact duplicate DNA in each daughter cell at the end. WHY IS CELL DIVISION NECESSARY Need for growth – a multicellular organism needs more cells as it grows and develops. Needed for repair – worn out or damaged cells need to be replaced. Some cells like your never cells and brain cells are not replaced often and take a long time to regenerate. Other cells like your skin cells are replaced all the time since they are more apt to be injured and exposed to a harsh environment. CHROMOSOMES The DNA that is passed on to new cells is carried on the chromosomes. So chromosomes carry the genetic information Every organism has a specific number of chromosomes – 46 in humans (23 pairs), 8 (4 pairs) in fruit flies, 48 in werewolves (24 pairs) and 50 in vampires (25 pairs) for those of you reading the Twilight series DNA REPLICATION DNA must replicate before mitosis (cell division) Each daughter cell needs an exact copy of the DNA Takes place in the nucleus DNA helicase (a group of enzymes)unzips the two DNA strands at one end (by breaking the hydrogen bonds between the bases) Free nucleotides bond with each strand of the DNA – until two new strands are made DNA REPLICATION After DNA is replicated; two identical sister chromatids exist. They will split apart later so each new cell has identical genetic material Short arm centromere Long arm cromatid MITOSIS AND CYTOKINESIS Mitosis is the dividing of the nucleus after DNA is replicated. Cytokinesis is the dividing of the cytoplasm at the very end INTERPHASE Consists of 3 phases G1 – period of cell growth S phase – key proteins and DNA molecules are synthesized and DNA is replicated G2 – once DNA replication is complete the cell enters G2 phase – many of the organelles and molecules need for cell division are made M PHASE mitosis (division of the nucleus) – 4 phases prophase, metaphase, anaphase and telophase (and cytokenesis – splitting of the cytoplasm)takes place CELL CYCLE http://www.cellsalive.com/cell_cycle.htm