BASIC ORGANIC CHEMISTRY RPD 12302 Mr. Maywan Hariono GENERAL SUBJECT OBJECTIVE LEARNING To introduce several organic compounds commonly found in life. To comprehend the basic organic chemistry concepts related pharmacy area SPESIFIC SUBJECT OBJECTIVE LEARNING To explain the students about organic nomenclature as a basic knowledge to understand the organic physic-chemical properties related pharmacy science such us pharmaceutics, pharmacology and pharmaceutical chemistry. To explain the students about the stereochemistry of organic compounds to support an adequate nomenclature of organic compounds. To explain the students about physical properties as a basic knowledge to understand another/further subject such as drug delivery system and pharmaceutical chemistry. To explain the students about several main organic chemical reaction as a basic knowledge to understand another/further subject such as pharmacology and pharmaceutical chemistry. STUDENT’S LEARNING OUTCOMES Be able to name the simple organic molecule structure & vice versa (draw the simple organic molecule name). Be able to name the simple organic molecule structure due to its stereochemistry & vice versa (draw the simple stereochemistry of organic compounds). Be able to explain the physical properties of main organic compounds. Be able to draw the simple organic chemical reactions. Be able to integrated all learning outcomes mentioned above in a simple organic drugs. ASSESMENT Formative (40%) - quiz : 5% - assignment/lab report :10% - mid exam (written) : 25% Summative: final exam (written) (60%) TOTAL (100%) INTRODUCTION TO ORGANIC CHEMISTRY Organic Chemistry is the chemistry of the compounds of carbon (C). The simple concept ” any substances that composed by carbon is derived from living organism” Whereas Inorganic nonliving resources (no carbon present, usually metal elements such as Na, K, Mg, etc). Other elements which is commonly presented in organic substances are hydrogen (H), oxygen (O) & nitrogen (N) Inorganic elements commonly presented in organic substances are Halogen (F, Cl, Br, I) DNA is the living resource element which composed by C, H, O & N. Carotene : orange pigment in carrot Our clothes are made from cottons Aspirin ( a pain killer) Paracetamol (fever reliever) Insulin (hormone), produced by pancreas, used in Diabetic Mellitus treatment So, what do u think about table salt, chlorophyll & hemoglobin ?? The key point to be successful in basic organic chemistry subject? Must be able to understand the properties of C, H, O & N Please review your Basic Physical Chemistry about electro negativity & chemical bonding What is electro negativity? Focused on C, H, O, N & Halogen What chemical bonds occurred in NaCl, H2O, HCl, CH4?? Ionic bonding??? Covalent bonding??? Hydrogen bonding??? What is the urgency of studying organic chemistry in Diploma in Pharmacy Program?? By understanding of basic organic chemistry students will be easy to integrate the concept with other subjects such as: Pharmaceutics: Basic Form., Intro Pharm., DDS 1, DDS 2. Pharmacology: Basic Pharmaco., Systemic Pharmaco., Autonomic Pharmaco. & Applied Pharmaco. Pharmaceutical Chemistry.