Chapter 3 Preexercise Evaluation Copyright © 2014 American College of Sports Medicine Introduction • Abbreviated versions of the preexercise evaluation described within this chapter are appropriate for low- and moderate-risk individuals wishing to engage in light-to-moderate intensity exercise within health/fitness settings. • High-risk individuals whether in health/fitness or clinical settings will require a more intensive medical evaluation prior to initiating an exercise program (see Chapter 2). Copyright © 2014 American College of Sports Medicine Introduction (cont.) • A comprehensive preexercise test evaluation in the clinical setting generally includes – a medical history, – a physical examination, and – laboratory tests. Copyright © 2014 American College of Sports Medicine Introduction (cont.) • A preexercise evaluation that includes a physical examination, an exercise test, and/or laboratory tests may be warranted for lower risk individuals whenever – the health/fitness and clinical exercise professional has concerns about an individual’s cardiovascular disease (CVD) risk, – requires additional information to design an Ex Rx, – or when the exercise participant has concerns about starting an exercise program of any intensity without such a medical evaluation. Copyright © 2014 American College of Sports Medicine Medical History, Physical Examination, and Laboratory Tests Box 3.1 Components of the Medical History • Medical diagnosis • Previous physical examination findings • History of symptoms • Recent illness, hospitalization, new medical diagnoses, or surgical procedures • Orthopedic problems • Medication use including supplements and drug allergies • Other habits including caffeine, alcohol, tobacco, or drug use • Exercise history • Work history • Family history Copyright © 2014 American College of Sports Medicine Box 3.2 Components of the Preparticipation SymptomLimited Exercise Test Physical Examination (7) Appropriate components of the physical examination may include the following: • Body weight; in many instances determination of body mass index, waist girth, and/or body composition (percent body fat) is desirable • Apical pulse rate and rhythm • Resting blood pressure: seated, supine, and standing • Auscultation of the lungs with specific attention to uniformity of breath sounds in all areas (absence of rales, wheezes, and other breathing sounds) • Palpation of the cardiac apical impulse and point of maximal impulse • Auscultation of the heart with specific attention to murmurs, gallops, clicks, and rubs • Palpation and auscultation of carotid, abdominal, and femoral arteries Copyright © 2014 American College of Sports Medicine Box 3.2 Components of the Preparticipation Symptom-Limited Exercise Test Physical Examination (7) (cont.) • Evaluation of the abdomen for bowel sounds, masses, visceromegaly, and tenderness • Palpation and inspection of lower extremities for edema and presence of arterial pulses • Absence or presence of tendon xanthoma and skin xanthelasma • Follow-up examination related to orthopedic or other medical conditions that would limit exercise testing • Tests of neurologic function including reflexes and cognition (as indicated) • Inspection of the skin, especially of the lower extremities in known patients with diabetes mellitus Adapted from (7). Copyright © 2014 American College of Sports Medicine Box 3.3 Recommended Laboratory Tests by Level of Risk and Clinical Assessment INDIVIDUALS AT LOW-TO-MODERATE RISK • Fasting serum total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides • Fasting plasma glucose, especially in individuals ≥45 yr and younger individuals who are overweight (body mass index ≥25 kg · m−2) and have one or more of the following risk factors for Type 2 diabetes mellitus: a first-degree relative with diabetes, member of a high-risk ethnic population (e.g., African American, Latino, Native American, Asian American, Pacific Islander), delivered a baby weighing >9 lb (4.08 kg) or history of gestational diabetes, hypertension (BP ≥140/90 mm Hg in adults), HDL cholesterol <40 mg · dL−1 (<1.04 mmol · L−1) and/or triglycerides ≥150 mg · dL−1 (≥1.69 mmol · L−1), previously identified impaired glucose tolerance or impaired fasting glucose (fasting glucose ≥100 mg · dL−1; ≥5.55 mmol · L−1), habitual physical inactivity, polycystic ovary disease, and history of vascular disease • Thyroid function, as a screening evaluation especially if dyslipidemia is present Copyright © 2014 American College of Sports Medicine Box 3.3 Recommended Laboratory Tests by Level of Risk and Clinical Assessment INDIVIDUALS AT HIGH RISK • Preceding tests plus pertinent previous cardiovascular laboratory tests (e.g., resting 12-lead ECG, Holter monitoring, coronary angiography, radionuclide or echocardiography studies, previous exercise tests) • Carotid ultrasound and other peripheral vascular studies • Consider measures of lipoprotein(a), high sensitivity C-reactive protein, LDL particle size and number, and HDL subspecies (especially in young individuals with a strong family history of premature CVD and in those individuals without traditional CVD risk factors) • Chest radiograph, if heart failure is present or suspected • Comprehensive blood chemistry panel and complete blood count as indicated by history and physical examination (see Table 3.4) Copyright © 2014 American College of Sports Medicine Box 3.3 Recommended Laboratory Tests by Level of Risk and Clinical Assessment PATIENTS WITH PULMONARY DISEASE • Chest radiograph • Pulmonary function tests (see Table 3.5) • Carbon monoxide diffusing capacity • Other specialized pulmonary studies (e.g., oximetry or blood gas analysis) BP, blood pressure; CVD, cardiovascular disease; ECG, electrocardiogram; HDL, high-density lipoprotein cholesterol; LDL, lowdensity lipoprotein cholesterol. Copyright © 2014 American College of Sports Medicine Blood Pressure Box 3.4 Procedures for Assessment of Resting Blood Pressure 1. Patients should be seated quietly for at least 5 min in a chair with back support (rather than on an examination table) with their feet on the floor and their arms supported at heart level. Patients should refrain from smoking cigarettes or ingesting caffeine for at least 30 min preceding the measurement. 2. Measuring supine and standing values may be indicated under special circumstances. 3. Wrap cuff firmly around upper arm at heart level; align cuff with brachial artery. 4. The appropriate cuff size must be used to ensure accurate measurement. The bladder within the cuff should encircle at least 80% of the upper arm. Many adults require a large adult cuff. 5. Place stethoscope chest piece below the antecubital space over the brachial artery. Bell and diaphragm side of chest piece appear equally effective in assessing BP (15). Copyright © 2014 American College of Sports Medicine Blood Pressure Box 3.4 Procedures for Assessment of Resting Blood Pressure (cont.) 6. Quickly inflate cuff pressure to 20 mm Hg above first Korotkoff sound. 7. Slowly release pressure at rate equal to 2–5 mm Hg · s−1. 8. SBP is the point at which the first of two or more Korotkoff sounds is heard (phase 1), and DBP is the point before the disappearance of Korotkoff sounds (phase 5). 9. At least two measurements should be made (minimum of 1 min apart) and the average should be taken. 10.BP should be measured in both arms during the first examination. Higher pressure should be used when there is consistent interarm difference. 11.Provide to patients, verbally and in writing, their specific BP numbers and BP goals. BP, blood pressure; DBP; diastolic blood pressure; SBP, systolic blood pressure. Modified from (23). For additional, more detailed recommendations, see (21). Copyright © 2014 American College of Sports Medicine Copyright © 2014 American College of Sports Medicine Blood Pressure (cont.) Lifestyle modification is the cornerstone of antihypertensive therapy: •Physical activity •Weight reduction (if needed) •DASH eating plan (i.e., a diet rich in fruits, vegetables, and low-fat dairy products with a reduced content of saturated and total fat), dietary sodium reduction (no more than 100 mmol or 2.4 g sodium · d−1) •Moderation of alcohol consumption Copyright © 2014 American College of Sports Medicine Blood Pressure (cont.) • The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) provides guidelines for hypertension detection and management (see Table 3.1). • According to JNC7, individuals with a systolic blood pressure of 120–139 mm Hg and/or a diastolic BP of 80–89 mm Hg have prehypertension and require health-promoting lifestyle modifications to prevent the development of hypertension. Copyright © 2014 American College of Sports Medicine Blood Pressure (cont.) • JNC7 emphasizes the fact that most patients with hypertension who require drug therapy in addition to lifestyle modification require two or more antihypertensive medications to achieve the goal BP (i.e., <140/90 mm Hg or <130/80 mm Hg for patients with diabetes mellitus or chronic kidney disease). Copyright © 2014 American College of Sports Medicine Copyright © 2014 American College of Sports Medicine Copyright © 2014 American College of Sports Medicine Copyright © 2014 American College of Sports Medicine Pulmonary Function • Pulmonary function testing with spirometry is recommended for all smokers >45 yr and in any individual presenting with – dyspnea (shortness of breath), – chronic cough, – wheezing, or – excessive mucus production. Copyright © 2014 American College of Sports Medicine Pulmonary Function (cont.) • Spirometric testing is also valuable in identifying patients with chronic disease (i.e., COPD and heart failure) with diminished pulmonary function that may benefit from an inspiratory muscle training program. Copyright © 2014 American College of Sports Medicine Pulmonary Function (cont.) Commonly used spirometry measurements: • Forced vital capacity (FVC) • Forced expiratory volume in one second (FEV1.0) • FEV1.0/FVC ratio • Peak expiratory flow (PEF) Copyright © 2014 American College of Sports Medicine Pulmonary Function (cont.) • The FEV1.0/FVC is diminished with obstructive airway diseases (e.g., asthma, chronic bronchitis, emphysema, chronic obstructive pulmonary disease [COPD]). • However, it remains normal with restrictive disorders (e.g., kyphoscoliosis, neuromuscular disease, pulmonary fibrosis, other interstitial lung diseases). Copyright © 2014 American College of Sports Medicine Copyright © 2014 American College of Sports Medicine Copyright © 2014 American College of Sports Medicine Copyright © 2014 American College of Sports Medicine Contraindications to Exercise Testing Assess Risk versus Benefit Copyright © 2014 American College of Sports Medicine Box 3.5 Contraindications to Exercise Testing ABSOLUTE • A recent significant change in the resting electrocardiogram (ECG) suggesting significant ischemia, recent myocardial infarction (within 2 d), or other acute cardiac event • Unstable angina • Uncontrolled cardiac dysrhythmias causing symptoms or hemodynamic compromise • Symptomatic severe aortic stenosis • Uncontrolled symptomatic heart failure • Acute pulmonary embolus or pulmonary infarction • Acute myocarditis or pericarditis • Suspected or known dissecting aneurysm • Acute systemic infection, accompanied by fever, body aches, or swollen lymph glands Copyright © 2014 American College of Sports Medicine Box 3.5 Contraindications to Exercise Testing (cont.) RELATIVEa • Left main coronary stenosis • Moderate stenotic valvular heart disease • Electrolyte abnormalities (e.g., hypokalemia or hypomagnesemia) • Severe arterial hypertension (i.e., systolic blood pressure [SBP] of >200 mm Hg and/or a diastolic BP [DBP] of >110 mm Hg) at rest • Tachydysrhythmia or bradydysrhythmia • Hypertrophic cardiomyopathy and other forms of outflow tract obstruction • Neuromotor, musculoskeletal, or rheumatoid disorders that are exacerbated by exercise • High-degree atrioventricular block Copyright © 2014 American College of Sports Medicine Box 3.5 Contraindications to Exercise Testing (cont.) RELATIVEa (cont.) • Ventricular aneurysm • Uncontrolled metabolic disease (e.g., diabetes, thyrotoxicosis, or myxedema) • Chronic infectious disease (e.g., HIV) • Mental or physical impairment leading to inability to exercise adequately aRelative contraindications can be superseded if benefits outweigh the risks of exercise. In some instances, these individuals can be exercised with caution and/or using low-level endpoints, especially if they are asymptomatic at rest. Modified from (11) cited 2007 June 15. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12356646 Copyright © 2014 American College of Sports Medicine Contraindications to Exercise Testing (cont.) • Patients with absolute contraindications should not perform exercise tests until such conditions are stabilized or adequately treated. • Patients with relative contraindications may be tested only after careful evaluation of the risk–benefit ratio. • Contraindications might not apply in certain specific clinical situations such as soon after an acute myocardial infarction, a revascularization procedure, or bypass surgery or to determine the need for or benefit of drug therapy. Copyright © 2014 American College of Sports Medicine Contraindications to Exercise Testing (cont.) For conditions that preclude reliable diagnostic ECG information, the exercise test may still provide useful information on: • Exercise capacity • Subjective symptomatology • Pulmonary function • Dysrhythmias • The hemodynamic responses to exercise Additional evaluative techniques such as ventilatory expired gas analysis, echocardiography, or nuclear imaging can be added. Copyright © 2014 American College of Sports Medicine Contraindications to Exercise Testing (cont.) • Emergency departments may perform a symptomlimited exercise test on patients who present with chest pain (i.e., 8–12 h after initial evaluation) and meet the indications outlined in Table 3.6. • This practice – appears safe in appropriately screened patients, – may improve diagnostic accuracy, and – may reduce cost of care. Copyright © 2014 American College of Sports Medicine Contraindications to Exercise Testing (cont.) • Generally, these patients include those who are no longer symptomatic and who have unremarkable ECGs and no change in serial cardiac enzymes. • Exercise testing in this setting should be performed only as part of a carefully constructed patient management protocol and only after patients have been screened for high-risk features or other indicators for hospital admission. Copyright © 2014 American College of Sports Medicine 25. Stein RA, Chaitman BR, Balady GJ, et al. Safety and utility of exercise testing in emergency room chest pain centers: an advisory from the Committee on Exercise, Rehabilitation, and Prevention, Council on Clinical Cardiology, American Heart Association. Circulation. 2000;102(12):1463–7. Copyright © 2014 American College of Sports Medicine Informed Consent • Obtaining adequate informed consent from participants before exercise testing and participation in an exercise program is an important ethical and legal consideration. • Although the content and extent of consent forms may vary, enough information must be present in the informed consent process to ensure that the participant knows and understands the purposes and risks associated with the test or exercise program. Copyright © 2014 American College of Sports Medicine Informed Consent (cont.) • The consent form should be verbally explained and include a statement indicating that the patient has been given an opportunity to ask questions about the procedure and has sufficient information to give informed consent. • Note specific questions from the participant on the form along with the responses provided. Copyright © 2014 American College of Sports Medicine Informed Consent (cont.) • The consent form must indicate that the participant is free to withdraw from the procedure at any time. • If the participant is a minor, a legal guardian or parent must sign the consent form. • It is advisable to check with authoritative bodies (e.g., hospital risk management, institutional review boards, facility legal counsel) to determine what is appropriate for an acceptable informed consent process. Copyright © 2014 American College of Sports Medicine Informed Consent (cont.) • All reasonable efforts must be made to protect the privacy of the patient’s health information (e.g., medical history, test results) as described in the Health Insurance Portability and Accountability Act (HIPAA) of 1996. • No sample form should be adopted for a specific test or program unless approved by local legal counsel and/or the appropriate institutional review board. • When the exercise test is for purposes other than diagnosis or exercise prescription (i.e., for experimental purposes), this should be indicated during the consent process and applicable policies for the testing of human subjects must be implemented. Copyright © 2014 American College of Sports Medicine Informed Consent (cont.) • Because most consent forms include a statement that emergency procedures and equipment are available, the program must ensure that available personnel are appropriately trained and authorized to carry out emergency procedures that use such equipment. • Written emergency policies and procedures should be in place, and emergency drills should be practiced at least once every 3 mo or more often when there is a change in staff. Copyright © 2014 American College of Sports Medicine Participant Instructions • Participants should refrain from ingesting food, alcohol, or caffeine or using tobacco products within 3 h of testing. • Participants should be rested for the assessment, avoiding significant exertion or exercise on the day of the assessment. • Clothing should permit freedom of movement and include walking or running shoes. Women should bring a loose fitting, short-sleeved blouse that buttons down the front and should avoid restrictive undergarments. Copyright © 2014 American College of Sports Medicine Participant Instructions (cont.) • If the evaluation is on an outpatient basis, participants should be made aware that the exercise test may be fatiguing and that they may wish to have someone accompany them to the assessment to drive them home afterward. Copyright © 2014 American College of Sports Medicine Participant Instructions (cont.) • If the exercise test is for diagnostic purposes, it may be helpful for patients to discontinue prescribed cardiovascular medications, but only with physician approval. Currently prescribed antianginal agents alter the hemodynamic response to exercise and significantly reduce the sensitivity of ECG changes for ischemia. Patients taking intermediate- or high-dose β-blocking agents may be asked to taper their medication over a 2- to 4-d period to minimize hyperadrenergic withdrawal responses (see Appendix A). Copyright © 2014 American College of Sports Medicine Participant Instructions (cont.) • If the test is for functional or exercise prescription purposes, patients should continue their medication regimen on their usual schedule so that the exercise responses will be consistent with responses expected during exercise training. Copyright © 2014 American College of Sports Medicine Participant Instructions (cont.) • Participants should bring a list of their medications including dosage and frequency of administration to the assessment and should report the last actual dose taken. As an alternative, participants may wish to bring their medications with them for the exercise testing staff to record. • Participants should drink ample fluids over the 24-h period preceding the test to ensure normal hydration before testing. Copyright © 2014 American College of Sports Medicine The Bottom Line The ACSM Exercise Testing Summary Statements are the following: • The preexercise evaluation is vital to ensuring exercise training can be safely initiated. • Regardless of whether or not an exercise test is indicated prior to starting a physical activity program, identifying known CVD risk factors (see Table 2.2) is important for patient management. • Exercise testing information can be used to counsel an individual regarding the risk for developing CVD, tayloring the lifestyle intervention program (i.e., exercise, diet, and weight loss) to potentially ameliorate CVD risk factors, and when appropriate, refer to the appropriate health care professional for additional assessment. Copyright © 2014 American College of Sports Medicine The Bottom Line (cont.) • In those individuals who require exercise testing, absolute and relative contraindications must be considered before initiating the assessment (see Box 3.5). • Individuals undergoing an exercise test should receive detailed instructions regarding the procedure and complete an informed consent document. Copyright © 2014 American College of Sports Medicine