Biomolecule Research Project What you are responsible for: 1. Learning as much as you can about one of the biomolecules (Carbohydrates, Proteins, Lipids, and Nucleic Acids) 2. Creating an advertisement that has all the important information over your biomolecule 3. Teaching/ Selling your biomolecule to the class in an interesting and creative way. How will I learn about my biomolecule that I am selling? You will be placed in pairs to research and create your advertisement about one of the four classes of biomolecules. Monday is the only day designated for in class research. You will be provided basic information about your biomolecule. You are expected to go more in depth that what is provided to you and include pictures of your biomolecule. Anything you do not finish in class will be homework due ____________ . Friday is scheduled to be in class time to make your advertisement. You will be required to turn in a script and have a finished product by the end of Thursday. On Monday, we will start presentations of your sales pitch for your biomolecule. How will I be graded? You will be graded by your peers and your teacher based on the following rubric. On target 3 Preparedness Focus on task Working with others Content written in notes was correct and highlighted the important information from the assigned part of the text Stays on task the majority of time Can self-redirect without the teacher redirection Student works as a team player in the small group to gain information and to help others Quality of teaching product Presentation of information Product contained all the information required All information was correct Creative presentation of material Clearly Organized Presentation of information to home group was organized, understandable, and accurate Approaching the target 2 Content written in notes was somewhat correct and mostly highlighted the important information from the assigned part of the text Somewhat stays on task in expert and home groups Sometimes needs redirection from teacher Student somewhat works as a team player in the small group to gain information and to help others Product contained some of the information required Some of the information was correct Some creative effort of material Missing the target 1 Content written in notes was not correct and does not highlight the important information from the assigned part of the text Rarely or Does Not stay on task in expert and home groups Frequently needs redirection from teacher Student did not work as a team player in the small group to gain information and to help others Product contained none of the information required None of the information was correct No effort was placed into product Not Organized Somewhat organized Presentation of information to home group was somewhat organized, understandable, and accurate Presentation of information to home group was not organized, understandable, and accurate Biomolecule Research Project Name of Presenter: Please rate the way your expert taught you the biomolecule material using the following rating system: 1 2 3 4 1= Expert presenter was hard to follow. I am so lost. 2= Expert presenter taught some of the material. I still need to study on my own. 3= Expert presenter was mostly clear, some concepts I am still not certain on. 4= Expert presenter clearly communicated the concepts in a way I get. I know the material now. Additional comments: _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Name of Presenter: Please rate the way your expert taught you the biomolecule material using the following rating system: 1 2 3 4 1= Expert presenter was hard to follow. I am so lost. 2= Expert presenter taught some of the material. I still need to study on my own. 3= Expert presenter was mostly clear, some concepts I am still not certain on. 4= Expert presenter clearly communicated the concepts in a way I get. I know the material now. Additional comments: Biomolecule Research Project Name of Partner:_________________________________ Please rate your partner and their participation during the project using the following rating system: 1 2 3 4 5 5 – Did an excellent job, took the lead on the project and completed most of it. My partner was great to work with; I would want to work with them again on any project. 4 – Did a great job, my partner and I worked together as a team to complete to project. Our efforts were a 50/50 split. 3 – Did an okay job, my partner and I worked together but I did more of the work. 2 – Did the job, my partner and I worked on the project, but we did not work well together. I did most of the work. 1 – Didn’t do the job, my partner and I were assigned to work together but I did everything alone. _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Name of Partner: ________________________________ Please rate your partner and their participation during the project using the following rating system: 1 2 3 4 5 5 – Did an excellent job, took the lead on the project and completed most of it. My partner was great to work with; I would want to work with them again on any project. 4 – Did a great job, my partner and I worked together as a team to complete to project. Our efforts were a 50/50 split. 3 – Did an okay job, my partner and I worked together but I did more of the work. 2 – Did the job, my partner and I worked on the project, but we did not work well together. I did most of the work. 1 – Didn’t do the job, my partner and I were assigned to work together but I did everything alone. Biomolecule Research Project Carbohydrates Function: Carbohydrates can be simple sugars or complex molecules containing multiple sugars. Carbohydrates are used by the cells of the body in energy-producing reactions and as structural materials. The three main types of carbohydrates you need to know are monosaccharides, disaccharides, and polysaccharides. A monosaccharide, or simple sugar, is the simplest form of a carbohydrate. The most important monosaccharide is glucose (C6H12O6), which is used in cellular respiration to provide energy for cells. Monosaccharides with five carbons (C5H10O5) are used in compounds such as genetic molecules (RNA) and high-energy molecules (ATP). A disaccharide is a sugar consisting of two monosaccharides bound together. A polysaccharide is a carbohydrate containing three or more monosaccharide molecules. Polysaccharides, usually composed of hundreds or thousands of monosaccharides, act as a storage form of energy and as structural material in and around cells. Starch, made solely of glucose molecules linked together, is the storage form of choice for plants. Animals store much of their energy in the form of glycogen, which is most often found in liver and muscle cells. Glycogen is formed by linking many glucose molecules together. Made by: Carbohydrates are generally made in the chloroplast; glucose is an example of a carbohydrate made in the chloroplast a s a product of photosynthesis. Disaccharides are made when two sugar molecules are joined by a reaction know as dehydration synthesis. A water molecule is removed to link the two sugars together. To break the bond in a disaccharide or polysaccharide water is added to split the molecule into simple sugars, this chemical reaction is called hydrolysis. Examples: The most important monosaccharide is glucose (C6H12O6), which is used in cellular respiration to provide energy for cells. Common disaccharides include sucrose, maltose, and lactose. Sucrose, a major energy carbohydrate in plants, is a combination of fructose and glucose; maltose, is a combination of two glucose molecules; and lactose, found in dairy products, is a combination of galactose and glucose. The most important carbohydrates for storing energy are starch and glycogen. Two important structural polysaccharides are cellulose and chitin. Structure: Carbohydrates have the elements C, H, and O. Carbon, Hydrogen and oxygen are present in a 1:2:1 ratio. Sometimes carbohydrates appear as 6 sided ring structures. Biomolecule Research Project Lipids Function: Lipids are organic compounds used by cells as long-term energy stores or building blocks. Lipids are hydrophobic and insoluble in water because they contain a hydrocarbon tail of CH2s that is nonpolar and repellant to water. The most important lipids are triglycerides (fats), oils, steroids, and phospholipids. They are not as easily metabolized as carbohydrates, yet they are a more effective means of storage; for instance, one gram of fat provides two times the energy of one gram of carbohydrate. Most of the fat found in animals is saturated, whereas plants tend to contain unsaturated fats. Phospholipids and some steroids compose the cell membrane. Made by: Lipids are made by the smooth ER in cells. Examples: The most important lipids are fats, oils, steroids, waxes, and phospholipids. One example of a steroid is cholesterol, an important structural component of cell membranes that serves as a precursor molecule for another important class of steroids: the sex hormones (testosterone, progesterone, and estrogen). Structure: Triglycerides (fats), are lipids made by combining glycerol and three fatty acids are used as long-term energy stores in cells and insulation in organisms. Fats can be saturated or unsaturated. Saturated fat molecules contain no double bonds. Unsaturated fats contain one (mono-) or more (poly-) double bonds, which means that they contain fewer hydrogen molecules per carbon than do saturated fats. Steroids are lipids composed of four carbon rings that look like chicken-wire fencing in pictorial representations. Phospholipids have a hydrophilic head region and 2 hydrophobic tails. Biomolecule Research Project Proteins Function: A protein is a compound composed of chains of amino acids. Proteins have many functions in the body—they serve as structural components, transport aids, enzymes, and cell signals, to name only a few. An amino acid consists of a carbon center surrounded by an amino group, a carboxyl group, hydrogen, and an R group. The R stands for "rest" of the compound, which provides an amino acid's unique personal characteristics. For instance, acidic amino acids have acidic R groups; basic amino acids have basic R groups, and so forth. Proteins can be found in the cell membrane to transport molecules across the cell membrane. Enzymes regulate the rate of chemical reactions by lowering the activation energy required for that reaction. Made by: Proteins are made in the ribosomes of cells. Examples: Structural proteins include keratin in the hair and horns of animals and collagen in connective tissues, and silk in spider webs. Transport proteins include hemoglobin which is responsible for transporting oxygen. Storage proteins such as casein in milk and ovalbumin in egg white. Defensive proteins like antibodies provide protection against foreign substances. Enzymes regulate the rate of chemical reactions. Structure: Primary structure. The order of the amino acids that make up the protein. Think of this like beads on a string. Secondary structure. Three-dimensional arrangement of a protein caused by hydrogen bonding at regular intervals along the polypeptide backbone. This would be like the chain of amino acids folding upon itself to make either a beta pleated sheet or an alpha helix. Tertiary structure. Three-dimensional arrangement of a protein caused by interaction among the various R groups of the amino acids involved. Quaternary structure. The arrangement of separate polypeptide "subunits" into a single protein. Not all proteins have quaternary structure; many consist of a single polypeptide chain. Biomolecule Research Project Nucleic Acids Function: The nucleic acids are the building blocks of living organisms. DNA is just one type of nucleic acid, it is considered the blueprint for . Some other types are RNA, mRNA, and tRNA. All of these "NAs" work together to help cells replicate and build proteins. DNA stands for deoxyribonucleic acid. RNA stands for ribonucleic acid. The mRNA and tRNA are messenger RNA and transfer RNA, respectively. You may even hear about rRNA which stands for ribosomal RNA. They are called nucleic acids because scientists first found them in the nucleus of cells. Now that we have better equipment, nucleic acids have been found in mitochondria, chloroplasts, and cells that have no nucleus, such as bacteria and viruses. ATP – adenosine triphosphate is the energy molecule in the cell. It transports energy in the phosphate bonds, which is released when the bonds are broken. ATP is a multifunctional nucleotide, most important as the "molecular currency" of intracellular energy transfer. Made by: ATP is produced during cellular respiration in the mitochondria and is consumed by a multitude of cellular processes. It is also incorporated into nucleic acids in DNA replication and transcription. DNA and they various RNAs are formed in the nucleus. Examples: Deoxyribonucleic acid is a nucleic acid containing the genetic instructions used in the development and functioning of all known living organisms. Ribonucleic acid (RNA) functions in converting genetic information from genes into the amino acid sequences of proteins. tRNA serves as the carrier molecule for amino acids to be used in protein synthesis, and is responsible for decoding the mRNA. ATP, the energy molecule in the cell is another type of amino acid. Structure: There are five easy parts of nucleic acids. All nucleic acids are made up of the same building blocks (monomers). Chemists call the monomers "nucleotides." The five pieces are uracil, cytosine, thymine, adenine, and guanine. No matter what science class you are in, you will always hear about ATCG when looking at DNA. Uracil is only found in RNA. Just as there are twenty (20) amino acids needed by humans to survive, we also require five (5) nucleotides. These nucleotides are made of three parts: 1. A five-carbon sugar 2. A base that has nitrogen (N) atoms 3. An ion of phosphoric acid known as phosphate (PO43-) We already told you about the big nucleic acids (DNA, mRNA, tRNA). They are actually made up of chains of base pairs of nucleic acids stretching from as few as three to millions. When those pairs combine in super long chains (DNA), they make a shape called a double helix. The double helix shape is like a twisted ladder. The base pairs are the rungs. Biomolecule Research Project Student note form What is your biomolecule? ______________________________________ What is the function of your biomolecule: Where is it made and how (if applicable): What are examples of you biomolecule: Sketch the structure of your biomolecule: