Performance Enhancing Drugs and Analysis

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What do these
sportsman have
in common?
Performance Enhancing Drugs
and Chemical Analysis
How did the world know?
The Ben Johnson Story
(click on the link-you will
have to register)
Can you name the
sporting persons?
Questions
1. Give the names of 3 performance
enhancing drugs available to the modern
athlete and give a brief description of how
they improve the athletes performance.
David Millar Story
(Click on the link)
2. Name some of the methods chemists
use to detect these drugs
Questions
3. One of the most important
methods is GC-MS (Gas
chromatography-mass
spectroscopy). What does this
method involve and use a simple
diagram to illustrate your points.
4. Some sports people and
scientists suggest that
performance enhancing drugs
should be legalised. What are
you feelings about this and why?
Paper Chromatography
Chromatography is used to separate mixtures of coloured or non-coloured
substances that are soluble in the same solvent. Paper chromatography is the
simple method of doing this.
spot of
mixture
solvent
A spot of the mixture is placed on some filter paper.
In method A, the solvent is soaked up the paper.
The substances in the mixture get separated because more soluble
substances spread along the paper faster.
Chromatography Experiment
Identifying dyes in a mixture
Chromatography can be used to find out if a dye is made up of a single
coloured substance or a mixture.
The
mixture
consists of
dyes
3 and 5.
1 2
3
4 5 6
mixture
1 2
3
4 5 6
mixture
Dots of known single dyes are placed alongside the dot for the unknown
mixture.
After the solvent washes through the paper, the pattern of the dyes in the
mixture is compared with the single dyes.
Which dyes does the mixture consist of?
Identifying dyes in a mixture
Which dyes are in the mixture?
1
2
3
4
5
6
mixture
1
2
3
4
5
6
mixture
The mixture consists of dyes
1 and 4.
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