P16081: SYSTEMIC
CIRCULATION MODEL
Jacob Zaremski – Lead Engineer
Mallory Lennon – Project Manager
John Ray – Communications Manager
Fabian Perez – Purchasing Coordinator
Robert Kelley – Document Control/EDGE Coordinator
Agenda
Our goals for this review
Updates from Phase I Review (Background)
10 minutes
5 minutes
10 minutes
5 minutes
15 minutes
5 minutes
2 minutes
• Engineering Requirements
• Customer Requirements
• Market Analysis
Functional Decomposition
Concept Development
System Architecture
Engineering Analysis
Risk Assessment
Project Plans
Goals
1. Receive feedback
2. Identify obstacles between current state and desired
end goal
3. Clarify feedback
4. Create action plan for each
Project Statement
• Develop a physical model of systemic
circulation
• Provide a teaching tool that will validate
theoretical models from Chapter 5 of Feher
• Measure relevant outputs: pressure and flow
• Interface with P16080 project
Use Scenario
Marketing Potential
•
Quantitative Human
Physiology: An Introduction
by Joseph J. Feher
($119.95 @ RIT
B&N)
• Add lab fee
$15/student/semester
•
•
Average 70
students/semester
Covers ability to build new
system each semester (if
desired)
• Add model as addition to
purchasing textbook
• Add lab experiment and
computer program as
additional costs
1
Customer Requirements (1 of 2)
Customer Requirements (2 of 2)
Engineering Requirements (1 of 2)
Engineering Requirements (2 of 2)
System Architecture
Flow Diagram
Functional Decomposition
Morph Chart (1 of 2)
Morph Chart (2 of 2)
Concept Selection Criteria
Design Concepts
Pugh Chart (1 of 3)
Pugh Chart (2 of 3)
Pugh Chart (3 of 3)
Preliminary Engineering Analysis
•
Lumped Parameter Model
•
Governing Equations
•
Critical Parameters and Ranges
Lumped Parameter Model
Lumped Parameter Model
Cardiac Output
Venous Return
Qc
QR
P16081 Pump
Arterial
Compliance,
CA
Pressure, PA
Resistance, RA
Resistance, RV
Capillary
Compliance,
CC
Venous
Compliance,
CV
Pressure, PV
Resistance, RC
Pressure, PC
v
Subsystem Model
Governing Equations: Flow
Measured
Defined
2
Governing Equations: Resistance
• Poiseuille’s Law
Governing Equations: Compliance
Tygon Tubing
- has been shown to have physiologically relevant
compliance
- higher wall hardness for arterial, softer for
venous
7
Fluid Capacitors
Spring piston
Air chamber acts as spring
Spring piston
For A = 10 in2:
(Woodruff et al, 1997)
Cylindrical Tank
P
Compliance Range: 1-200 mL/mmHg
Rectangular Prism Tanks
P
P
CArterial
CVenous
Compliance Range: 1-200 mL/mmHg
Concept Risks
Technical Risks
Resource Risks
Safety Risks
Environmental Risks
Theoretical Risk Assessment
Project Plans Phase 2
Project Plan Phase 3
Next Steps
•
Engineering Analysis
•
Budget Feasibility
•
Iterate Pugh Chart
•
Collaboration with P16080
•
PASCO sensors
Concerns
1. Lacking sufficient background knowledge to
make supported decisions about system
components
2. Accurately modeling textbook models and
what precision we will be able to achieve
3. Creating the software interface to run system
and/or record desired outputs
4. Possible sources of error that are neglected in
calculations
Acknowledgements
RIT Faculty
• Dr. Jennifer Bailey
• Dr. Steven Day
U of R Faculty
• Dr. Schwartz
• Dr. Doran Mix
Guide
• Gerald Garavuso
Sources
1.
2.
3.
4.
5.
6.
7.
8.
9.
http://www.amazon.com/Quantitative-Human-Physiology-Introduction-Engineering/dp/0123821630
Feher, Joseph J. Quantitative Human Physiology: An Introduction. Amsterdam: Elsevier/Academic,
2012. Print.
F. M. Donovan. Design of a Hydraulic Analog of the Circulatory System for Evaluating Artificial Hearts,
Biomaterials, Medical Devices, and Artificial Organs, 1975, 3:4, 439-449.
https://www.google.com/search?q=needle+valve&espv=2&biw=1149&bih=659&source=lnms&tbm=is
ch&sa=X&ved=0CAYQ_AUoAWoVChMIjIOY0-ieyAIVCqYeCh2pJwgr#imgrc=WwAmF7IltMl6-M%3A
http://www.terrybookers.co.uk/35mm-gate-valve-2226-p.asp
http://www.hassmfg.com/search.pl/1213638750-2927?keyword=1165
Varble N, et al. In vitro hemodynamic model of the arm arteriovenous circulation to study
hemodynamics of native arteriovenous fistula and the distal revascularization and interval ligation
procedure, Journal of Vascular Surgery, 2013, 59:5, 1410-1417.
Linearization and nonlinear fluid elements - Dartmouth College
http://www.dartmouth.edu/~sullivan/22files/linearization_and_fluid.pdf
Woodruff, Stewart J., Keith M. Sharp, and George M. Pantalos. "Compact Compliance Chamber
Design for the Study of Cardiac Performance in Microgravity." ASAIO Journal (1997): 316-20. Web.
30 Sept. 2015.
ADDITIONAL SLIDES
Customer Requirements Mapping (1 of 2)
Customer Requirements Mapping (2 of 2)