Thought, Mood and Somatoform Disorders When comparing the “newer” high potency antipsychotic meds, such as haloperidol & droperidol to the “older” low potency antipsychotic meds, such as chlorpromazine, haloperidol drugs cause which of the following side effects? A. More extrapyramidal symptoms B. More cardiovascular toxicity C. More orthostatic hypotension D. More sedation E. All of the above Compared to droperidol, haloperidol does which of the following? A. Causes more sedation than droperidol B. Has a faster onset of action than droperidol C. Has a shorter duration of action than droperidol D. Has more antipsychotic activity than droperidol E. Requires higher doses than droperidol A 32yo F c/o 4 days of anxiety, restlessness, and an inability to stop moving. 2 days ago her doctor increased her haloperidol from 2 mg PO bid to 4 mg PO bid, with no change in her symptoms. Appropriate management includes: • A. Haldol to 6mg PO bid, & f/u tomorrow w/ 1°MD • B. Stop Haldol, start clozapine, and f/u in AM w/ her primary physician. • C. Haldol to 1 mg PO bid, add benztropine 1 mg PO tid, & f/u in AM w/ 1°MD • D. Stop Haldol, give dantrolene 1mg/kg IV, & admit to the hospital. • E. Admit for management of her decompensating psychosis. Which of the following is INCORRECT regarding dystonic reactions from neuroleptic medications: • A. Torticollis • B. Laryngospasm • C. Motor restlessness • D. Sustained upward deviation of the eyes • E. Symptoms decrease with voluntary activities and increase with stress Which is the correct diagnosis of a 28yo M on chronic neuroleptic drug therapy presenting to the ED w/ complaints of involuntary wiggling movements of his face and tongue? A. Akinesia B. Dystonia C. Neuroleptic malignant syndrome D. Tardive dyskinesia E. None of the answers Psychotic symptoms can be clinically sorted into four categories. Which of the following is NOT one of these categories? A. Aggressive behavior disorders B. malingering or factitious C. brief reactive psychosis D. functional psychosis E. organic brain syndrome What drug could potentiate symptoms of a phenothiazine overdose? • • • • • A. Magnesium sulfate B. Phenytoin C. Lidocaine D. Procainamide E. Amiodarone After a very traumatic or stressful experience, a previously healthy patient develops acute confusion, hallucinations and bizarre behavior. Choose the correct diagnosis assuming symptoms last less than two weeks. A. B. C. D. brief reactive psychosis schizophreniform disorder paranoid disorder stress induced transient psychosis Depression during childhood and adolescent years is seen in 10 to 20% of the patients seen in child psychiatry clinics. In samples of normal schoolchildren and adolescents, what percentage meet diagnostic criteria for depression? A. B. C. D. 0.5-2% 2-5% 5-10% 10-15% Which of the following is a risk factor for child suicide? A. 2-parent family B. family history of suicide C. close peer relationships D. presence of chronic disease E. family history of epilepsy Life-threatening sympathomimetic rxns can occur when MAO inhibitors are combined w/ the wrong meds. Which of the following is NOT a MAO inhibitor? A. B. C. D. tranylcypromine (Parnate) phenelzine (Nardil) selegiline (Eldepryl) pergolide (Permax) Tricyclic antidepressants increase the concentration of this neurotransmitter at the synapse by blocking presynaptic reuptake. A. B. C. D. norepinephrine or serotonin glutamate and epinephrine dopamine and GABA epinephrine and norepinephrine Most of the serious toxic effects of lithium occur at serum levels over 2 mEq/L, but mild adverse effects may be seen at levels of 1.5-2.0 mEq/L. Dehydration, salt restriction, diuretic use, childbirth and infection predispose patients to these side effects. Which of the following is NOT one of these side effects? A. Diarrhea B. Vomiting C. Drowsiness D. muscular weakness E. lack of coordination F. hypoglycemia What is the usual amount of time between manic and depressive episodes in bipolar patients? A. 1-4 years B. 1-2 months C. 2-3 weeks D. 6-12 months Which of the following is paired Incorrectly? A. Bupropion : potent anticholinergic/ antihistaminic effects & has cardiac/ neurotoxicity with overdose. B. Heterocyclic antidepressants: less side effects & toxicity relative to the tricyclics. C. Serotonin reuptake inhibitors: may cause anxiety, nausea, drowsiness; highly protein bound & may displace Coumadin and digoxin, increasing toxicity. Relatively nontoxic with overdose. D. Tricyclic antidepressants: highly anticholinergic and antihistaminic; cardiac and neurotoxicity with overdose (OD). ____ percent of patients with major depressive disorder die by suicide A. 1 % B. 4 % C. 15 % D. 30 % E. 35% Which of the following statements is INCORRECT? A. The sole presentation of porphyria may be psychiatric symptoms including anxiety, apathy, depression, or psychosis B. 10% of patients with Wilson's disease present with psychiatric problems including personality change, paranoia, depression, and catatonia. C. 20-40% of patients with severe adrenal insufficiency have depression and/or psychosis. D. Pancreatic cancer patients frequently suffer from anxiety prior to their diagnosis. E. There is a higher incidence of psychiatric disease in patients with thyroid disease Which of the following is characteristic of somatoform disorders? A. Giving drugs or substances to another person to produce symptoms B. Desire for painful tests or surgery in order to continue hospitalization C. Ingestion of substances to produce symptoms D. Intentional fabrication of symptoms for secondary gain E. Involuntary control of symptoms with the unconscious goal to be "sick" A 38year-old woman presents with a chronic history of headache, dizziness, nausea, fatigue, and dysmenorrhea. Her exam is normal. Which of the following is a likely diagnosis? A. Conversion disorder B. Factitious disorder C. Malingering D. Pain disorder E. Somatization disorder Which of the following is INCORRECT regarding characteristics of conversion disorder? A. Motivated by external incentive to feign illness (voluntary) B. Nonpainful, usually neurologic complaint C. Rapid onset D. Single organ system E. Without anatomic or physiologic explanation A 42yo woman has neck pain and headaches from a MVC 3 years ago. She presents to your ED with disabling neck pain. Her past work-up for neck pathology is negative and she is now on disability. What is the most likely diagnosis? A. Hypochondriasis B. Somatization disorder C. Somatoform pain disorder D. Factitious disorder E. Malingering Which of the following is NOT an example of a dissociative disorder? A. localized or selective dissociative amnesia B. dissociative fugue C. paranoid personality disorder D. dissociative identity disorder E. depersonalization disorder A 8 year old child presents with a cough that resolves with distraction & during sleep. After a neg exam, the child's chest is wrapped w/ a sheet & the child is told that the chest muscles are tired & that the sheet will cure the cough w/in 15 min. 15 min later the cough is gone. A.Conversion Disorder B. Panic Disorder C. Brief Reactive Psychosis D.Hypokalemia Some symptoms of schizophrenia are not as responsive to phenothiazine therapy as hallucinations & delusions. Which of the following is NOT one of these so-called "negative" symptoms? A. neologism and "word salad" (abnormal). B. blunted affect (lack of emotion). C. abulia (lack of volition). D. alogia (poverty of speech) Some brief psychotic syndromes are characterized by good premorbid functioning & a good prognosis compared to a formal chronic diagnosis of schizophrenia. Which of the following is NOT one of these ‘good prognosis’ syndromes? A. brief psychotic disorder or brief reactive psychosis B. transient paranoid disorder C. schizophreniform disorder D. substance induced psychotic disorder