Cell Division CELL CYCLE The cell cycle is divided into 3 main stages: Interphase, when the cell is carrying out its normal cellular functions and chromosomes are replicated, Mitosis when the nuclear division occurs and the cell splits. Cytokinesis- division of the cytoplasm 3 Stages of Interphase: The beginning of interphase The cell grows and develops. Protein Synthesis and other cell processes are occuring The cell is busy being a cell!! Pull Pull Interphase- *A cell spends 90% of its life in interphase. *Chromosomes are replicated. * A cell grows to full size. S T f of G2 Phase Pull Pull G1 Phase: Centriole DNA be starting The ce MITOSIS: Cell division Results: Mitosis results in 2 identical daughter cells that are diploid. Diploid: Cells that have 2 copies of each chromosome or a full set (2n) of genetic information (DNA). Somatic (body) cells are diploid. URPOSE OF MITOSIS: P Growth: Mitosis is how your body makes new cells so you can grow. URPOSE OF MITOSIS: P Repair: Mitosis is how your body repairs itself. The roots of your hair are always growing. URPOSE OF MITOSIS: P Your epidermis is constantly replacing new skin cells. The life span of skin cells in an adult is about 50 days. Maintenance: Replace cells life. In 3-4 months your whole blood supply is completely replaced. A blood cell lasts 60-120 days. Everyreplaced day 1% of throughout your blood cells are that are replaced. While you have been reading this sentence around 50,000 cells have died and been replaced. Other cells are never (or very slowly replaced, like skeletal muscle cells o neurons. The average age of all the cells in an adults body may turn out to be as young as 7-10 years old. Intestinal cells are replaced about every 5 days. WHAT DOES MITOSIS HAVE TO DO WITH ME? 1. Mitosis out of control = cancer 2. Mitosis that stops early =advanced aging or disease such as progeria 3. Many diseases are related to problems with cell division: *Cancer *Alzheimers *Parkinson's STAGES OF MITOSIS 2 3 4 5 1. Prophase: Centrioles Centrioles move the the sides (poles) of the cell. Spindle Fibers Spindle fibers start to form. Link to Chromosome Structure nuclear membrane The nuclear membrane dissolves Chromosome Chromatin winds up to form chromosomes. 2. Metaphase: Spindle Fibers Line Up A) Chromosomes line up in the center of the cell. B) ce 3. Anaphase: Chromosome Double stranded chromosomes separate. Spindle fibers anchored to centrioles pull the chromosomes towards the sides of the cell. 4. Telophase: Spindle Fibers B) Spindle fibers dissolve reform Interphase E) The cell will reenter interphase. Chromatin C) Chromosomes unwind to chromatin. Chromosome A) Chromosomes continue to moving to the sides of the cell. Cytokinesis Duration of Cell Cycle On average a cell takes 24 hours to complete the cell cycle. Of those 24 hours, approximately 22 hours the cell is in interphase (G1, S, and G2 Phases). Then it takes only 2 hours to complete mitosis (prophase telophase). Put the following stages of mitosis in order.