Transport-cell membrane • Do Now: • Brainstorm: • What is homeostasis? • Can you brainstorm one • What is transport? way that transport helps to maintain homeostasis in your body? (explain) Definitions….. • TRANSPORT • -absorption, distribution, circulation, cyclosis, osmosis, diffusion • HOMEOSTASIS • -maintaining a stable internal environment What does venom have to do with cell membranes? • Brown Recluse Spider Bite! Western Diamondback Rattlesnake bite! Vocabulary • Solution- mixture in which one or more substances are UNIFORMLY distributed in another. “homogenous solution” • Solute- what gets dissolved. • Solvent- what does the dissolving. • Ex- salt water- salt is solute, water is solvent. Ice tea- mix=solute, water=solvent Why is the cell membrane so important??? Names! • Cell membrane • Plasma membrane • Selectively permeable membrane • Semi permeable membrane Honors Know diagram on pg 82! • Variety of Proteins: • I. Glycoproteins a) b) c) d) e) Receptor protein Recognition proteins Enzymatic proteins Attachment proteins Transport proteins Functions of the Cell Membrane • • • • • Protects the cell Regulates what goes in and out of cell Helps to communicate with other cells Creates attachments between cells Dynamic! Fluid Mosaic Model dev. By Singer & Nicolson 1972 • Proteins move within layers of lipids w/I viscous fluid • Hydrogen bonds can form between water and phospholipid heads inside and outside of cell • The more double bonds there are in the tails the more fluid the membrane • Incr. in temp. causes membr. To be more fluid (because mol. Move faster) • Decr. Temp. (mol. Move slower -> less fluid) Active & Passive Transport Illustrations Chapter 5 Lab Biology Chapter 5 Honors Biology Passive Transport •Requires NO energy!! •Movement from a high concentration to a low concentration! Passive Transport • 1. diffusion • 2. osmosis • 3. facilitated diffusion • 4. diffusion through ion channels Diffusion Diffusion • Molecules moving from a greater concentration to a lower concentration • Ex: perfume • Simple diffusion: Oxygen, Carbon Dioxide, water and lipid soluble molecules Vocabulary • Concentration gradient: difference in concentrations (amount of solute) • Equilibrium: particles/molecules are equal on both sides of membrane More diffusion -> “equilibrium”!! Osmosis Osmosis •Movement of WATER from a high concentration to a low concentration across the cell membrane Iso – Hyper – Hypotonic Solutions Vocabulary • Isotonic: concentration inside and outside of cell are the same no diffusion • Hypertonic: when concentration of solute outside of cell is greater, water moves out of cell (shrink) • Hypotonic: concentration of solute inside of cell is greater, water moves into cell (burst) Plasmolysis Plants! • Plasmolysis = cell shrinks away from cell wall due to water loss ex: drought (low rain fall) causing plants to wilt • Turgor Pressure = cell wall sustains shape, otherwise would explode Facilitated Diffusion Facilitated Diffusion • Carrier Protein – -protein recognizes substance->changes shape->delivers substance to inside of the cell • Facilitated Diffusion: water soluble molecules (hydrophillic). Ex: ions, amino acids (small proteins), and sugars Ion Channels Ion channels • -allows ions Ca2+ and Cl- to enter cell • Some are open all the time • Others are gated and will open when – Cell membrane stretches – Electrical signals – Chemical signals Active Transport •REQUIRES ENERGY! •Movement from a LOW concentration to a HIGH concentation! Active Transport • 1. Sodium Potassium Pump • 2. Endocytosis • 3. Exocytosis Active Transport Sodium Potassium Pump • -pumps like to keep ions in balance • 3 Na+ out for every 2 K+ in • This creates a build up of Na+ outside cell and K+ inside cell forming a net electrical charge across the membrane • Allows for nerve impulses • Contraction of muscles • 1/3 of all energy in animal cells goes to running this pump even as we sleep! Endocytosis Endocytosis • Take in external fluid, macromolecules and other large particles. • Forms “vesicle” some fuse with lysosomes (digestion) others fuse with membrane of other organelles. • 2 Types: a) pinocytosis – cell drinking fluid • b) phagocytosis – cell eats Exocytosis opposite of endocytosis!!