Mitosis Review Lesson Get your brains in gear with the Mitosis game!! How much do you remember about mitosis? Listen to the song and see if you can fill in the blanks on your sheet! Group Activity Here is a summary of the stages of mitosis. Put the letters for each stage in the correct order… A. the chromosomes move to the equator of the cell spindle fibres attach each centromere to the poles B. each chromosome doubles up to form two identical chromatids the chromosomes shorten and thicken and become visible C. nuclear membranes form and the cytoplasm divides to make two identical cells D. the spindle fibres shorten and pull the chromatids apart the chromatids are pulled to the opposite ends of the cell Answer: BADC Group Sort It Out! 1. The chromosomes form replicas of themselves before division starts. 2. The chromosomes become visible as double structures, the nuclear membrane vanishes. 3. The chromosomes line up along the equator of the cell. 4. The chromatids are pulled apart by the spindle fibres. 5. A complete set of chromosomes is gathered at each end of the cell. 6. The cytoplasm divides and the nuclear membranes form to give two identical cells. Group Activity Can you identify which cells are in which stage? Tasks for this lesson • Complete the Mitosis worksheet • Try the Mitosis Modelling exercise -use some coloured chalks -go outside -as a group draw the process of mitosis out onto the ground -make sure everything is labelled! -DO NOT USE NOTES!! • Watch this summary of mitosis Timed extended answer response 1. Up to two additional marks are available for the construction of your answers.(2) (a) Before cell division in unicellular and multicellular organisms, the nucleus must divide to produce two genetically identical nuclei. Explain the events that occur in cells that result in the production of genetically identical nuclei. (8) (b) Suggest why cell division is necessary in multicellular organisms. (4) (Total 14 marks) 1.(a) mitosis; • DNA replication; • each chromosome consists of two sister / identical chromatids; • chromosomes condense / supercoiling; • nuclear membrane breaks down; • chromosomes align (at equatorial plate); • spindle fibres / microtubules attach to centromeres of chromosomes on opposite sides; • centromeres split; • chromatids become chromosomes; • sister / identical chromosomes pulled to opposite poles; • nuclear membranes reform; • events correctly assigned to interphase, prophase, metaphase, anaphase, and telophase; 8 max • NB: A correct sequence of idea should be recognized when awarding the quality mark for structure of the answer (linked ideas). (b) • more cells needed for growth; • repair / replacement; • cells specialize / differentiate for particular functions; • formation of reproductive cells (meiosis); • cells have to divide when they reach a certain size; • surface area to volume ratio becomes too small; • materials / oxygen / named material cannot be absorbed quickly enough; • rate of use of materials related to volume but rate of exchange related to SA; 4 max