Genetics Part 2: and Classic/Complete Dominance Classic Dominance: (aka “complete dominance”) the heterozygote displays the dominant phenotype. It doesn’t always work this way, though … Observation: A Litter of Puppies Which is Dad? Mom Dad 2 is the sire of the litter! Dad 1? Dad 2? How is that possible?? Many traits have complex inheritance. They can involve more than two alleles! (Example: blood types) May not be as simple as complete dominance Sometimes involves more than 1 gene! (Examples: eye color, height, skin color) In the case of the dogs shown in the previous two slides, there are 2 separate gene locations that control coat color. Incomplete Dominance: occurs when Incomplete Dominance offspring have a phenotype that is in between the two parent phenotypes. Heterozyote displays a blended phenotype (dominant no longer masks recessive!) Ex) Four o’clock flowers Get ready to write in the answers to the example and Square 1! Incomplete Dominance Example Four o’clock flowers (This is square 3 on your notes sheet) Genotype Phenotype RR Red Flowers rr White Flowers Rr Pink Flowers Show a cross between two heterozygous pink flowers. Rr X Rr R r R RR Rr Genotypic ratio: 1 RR : 2 Rr : 1 rr r Rr rr Phenotypic ratio: 1 Red : 2 Pink: 1 white There is only 1 genotype per phenotype! Now, you try it! Complete squares 2 and 3 on your fill-in notes sheet using the “rules” from our Four ‘O Clock Flowers example. Codominance: both alleles are expressed in a heterozygote. Neither allele is recessive! Both show up in the phenotype – there is no “in between” like with incomplete dominance. Codominance Examples: blood types, spotted cows, spotted flower color SPECIAL CASE: How to write genotypes for codominant alleles Notation: USE WITH CODOMINANCE ONLY! Example: Codominance in cow coat colors Represents the gene for coat color Genotype written as: The allele for the color R C CC R R (in this case, it is red) Phenotype written as: Red Codominance Example Roan Coat Color in Cattle Genotype Phenotype C R CR CWCW C R CW Red Coat White Coat Roan Coat Show a cross between a red bull and a roan cow. CRCR X CRCW CR CR C R CR CR CR CR C W CR CW CR CW Genotypic Ratio: 2 CR CR : 2 CR CW Phenotypic Ratio: 2 Red Coat : 2 Roan Coat Blood type = Codominance and Multiple Alleles There are 3 alleles for blood genotypes: IA, IB, i There are 4 blood phenotypes: A, B, O, AB IA and IB are codominant; both are expressed for blood type AB. Type O, which has genotype ii, is recessive to both A and B. Genotypes Phenotypes IA IA or IA i IB IB or IBi ii IA IB Type A Type B Type O Type AB Multiple alleles! The only one that is Codominant! Blood Type Example (write this down!) A woman has Type A blood and her genotype is IAi She marries a man who is Type B with genotype IBi. What are the possible blood types of their children? IB IA i IAIB i IAi Type AB Type A IBi ii Type B Type O The possible offspring blood types are: Type AB, Type A, Type B, and Type O Back to the dog example from yesterday… There are TWO alleles for Coat Color K = Black k = Not Black Y = Red y = Tri-color Dam (mom): KkYY Sire (dad): kkyy The Pups are: KkYy = Black kkYy = Red To Sum Up Classic Dominance: Dominant Phenotype Incomplete Dominance: X An “in between” of the dominant and recessive Codominance: X Both alleles are displayed