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Kansas Association of Nursing Students
Shan Nanji
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Thank You!
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Kansas Association of Nursing Students!
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About KISSPrep
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KISSPharm
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8 online programs

Live Test Prep in Miami

Nursing School and EMS School Coming Soon
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My Parents:
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My Dog, Hero…
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Stay Positive!
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Limitless
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Why is pharmacology so
important?
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Up to 25% or more of your NCLEX
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Used each and every day in practice
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New drugs introduced daily
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Most drugs administered by nurses
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Side effects monitored by… nurses!
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What is Cancer?
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Rapidly dividing cells
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Out of control, rapidly dividing cells…
Where are rapidly dividing cells located in a normal body?
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Skin
Hair
GI
Bone Marrow
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Vitamin/Pregnancy Connection
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Mechanism of Action Connection
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Why does this folate connection `matter…?
 Side

effects
Our method: understand concepts, don’t memorize
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ANS – Parasympathetic &
Sympathetic Basics
Parasympathetic
“CHOLinergic”
MUSCARINIC
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- Most
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Parasympathetic System
- CHOLinergic
 M1
– CNS/ENS
M2
– Heart
M3
– EG BB
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Increases Exocrine Gland Secretion
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Increases Gut Motility
 Bronchoconstriction
 Bladder contraction
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CHOLinergics
Bethanachol
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CHOLinergics
 BethanaCHOL
– Post op and neurogenic ileus and
urinary retention
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CHOLinergics
Methacholine
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CHOLinergics
 MethaCHOLine
– Induces bronchospasm used in
Asthma Challenge Test
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CHOLinergics
 Bethanachol
– Post op and neurogenic ileus and
urinary retention
 Methacholine – Induces bronchospasm used in
Asthma Challenge Test
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CHOLinergics
 BethanaCHOL
– Post op and neurogenic ileus and
urinary retention
 MethaCHOLine – Induces bronchospasm used in
Asthma Challenge Test
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Anti-ACh – Anti-Cholinergics
MOA:
So, if cholinergics agonize M3…
……………an Anti-ACh will ANTAGONIZE M3.
Antagonizing M3 will cause:
 Decrease
Exocrine Gland Secretions
 Decrease Gut Motility
 Bronchodilation
 Bladder relaxation
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Anti-ACh
 aTROPine,
HomaTROPine/TROPicamide:
Mydriasis w/Cyclopegia
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Anti-ACh
Benztropine
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Anti-ACh
 BenzTROPine – Lipid Soluble (CNS Entry) for
Parkinson's, and EPS Symptoms due to antipsychotics
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Let me break it down for ya…
Fat Soluble
Long Half Life
Small
Liver
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Anti-ACh
Ipratropium
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Anti-ACh
 IpraTROPium – Safe to use in Asthma and COPD
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Let me show you how it works…
Tiotropium Bromide
Tio-TROP-ium Bromide
Questions:
1)
What kind of drug is it?
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2)
What is it used for?
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3)
Anti-ACh (Anti Cholinergic)
COPD/Asthma. Brand name: Spiriva!
What is this drug’s mechanism of action?
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Blocks M3
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Tetracyclines “+-etracyclins”
MOA:
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Bacteriostatic
Bind to 30s
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Prevent Attachment of Aminoacyl-tRNA
Limited CNS Penetration
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DO NOT take with Milk, Antacids, or an Iron Containing Prep
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RESISTANCE:
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Shan Nanji - NanjiMD@gmail.com
Decrease Uptake Into Cells or
Increased Efflux Out of Cells by
Plasmid Encoded Transport Pumps
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Tetracyclines “+-etracyclins”
 RESISTANCE:
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Decrease Uptake Into Cells Or
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Increased Efflux Out Of Cells By Plasmid
Encoded Transport Pumps
Shan Nanji - NanjiMD@gmail.com
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Tetracyclines “+-etracyclins”
S/E:
GI Distress
 Discoloration of Teeth
 Inhibition of Bone Growth in Children
 Photosensitivity
 C/I in Pregnancy
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Shan Nanji - NanjiMD@gmail.com
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Tetracyclines “+-etracyclins”
 Thirty
S subunit
 Tummy
 Taller
 Transport
 Teratogen
Shan Nanji - NanjiMD@gmail.com
Pumps (resistance)
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Tetracyclines “+-etracyclins”
 Doxycycline
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Hepatic Excretion
 Demeclocycline
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ADH Antagonist
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Can be Used a Diuretic in SIADH
 Minocycline
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Effective against acne
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Effective against Rosacea
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“Mi–NO like acne”
Shan Nanji - NanjiMD@gmail.com
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Alpha and Beta Receptors
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Check, check, check it out!
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Understand Equations. Don’t
Memorize.
CO = SV * HR
Cardiac Output = Stroke Volume * Heart Rate
African Americans & Hispanics – High Sodium Diet
Middle Aged Caucasion Males – High Stress
Elderly Males - Atherosclerosis
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KISS Success Stories
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KISSPrep

Campus Visits
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Group Pricing for Classes/Institutions
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KISS Guarantee

100 % PASS Rate

25 Hours

Know what is right!

Money back guarantee

Tutor

Schedule

PASS!
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Exclusive Offers:

Pharmacology - 25 months: $134.95

Anatomy – 25 months: $134.95

NCLEX – 25 months: $239.95
Today’s Special Offer
Lifetime Access to Pharmacology + Lifetime Access to
Anatomy + 25 months NCLEX Only: $134.95
Lifetime access is ONLY offered at convention!
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