Chocolate Sweetens Fight Against High Blood Pressure for Some By: Karen Kaplan Los Angeles Times Presented By: Dan Pastor Hypertension • A condition where the force of blood against the artery walls is too high.* • Determined by the amount of resistance to blood flow in the arteries. • Blood pressure has 2 parts: – Systolic (top number) – Diastolic (bottom number) • A typical blood pressure is “120 over 80”. • Measured in mmHg *http://www.mayoclinic.com/health/high-blood-pressure/DS00100 Hypertension • Complications*: – – – – – – – Heart attack or stroke Aneurysm Heart failure Damage to blood vessels in the eyes Various metabolic problems Trouble with memory or understanding Many other conditions *http://www.mayoclinic.com/health/high-blood-pressure/DS00100/DSECTION=complications The Study* • Karin Ried and her colleagues at the University of Adelaide found that dark chocolate was superior to a placebo in reducing hypertension. • Studies lasted from 2 to 18 weeks. • Participants were given daily doses of chocolate that ranged from 50% to 70% cocoa. • Daily doses of flavanol ranged between 30mg and 1000mg. *Ried et al. BMC Medicine 2010, 8:39 The Results • Ried, et al. found that for those with hypertension and pre-hypertension: SBP: -5.0 ± 3.0 mmHg; P = 0.0009 DBP: -2.7 ± 2.2 mmHg; P = 0.01 • For those with normal BP, no significant effects. HTN Statistics* • Affects 32% of adults over 20. • In 2006, 40.5 million ambulatory care visits with HTN as primary diagnosis (3.6%). • 23,965 deaths in 2007 • 7.9 per 100,000 *http://www.cdc.gov/nchs/fastats/hyprtens.htm C Economics C: Home Good H: Health M: Medical Good X: Non-Medical Good C = C(X) Less M, but same H More C and X X H Y(H) = pX + qM H2 = H (M2) From: Zweifel and Breyer, Dr. Goodman, Lecture #2 H1 = H (M1) M Conclusions • Chocolate did not reduce mean SBP below 140mmHg, or mean DBP below 80mmHg. • 2 people dropped out of a previous study by Ried because they found dark chocolate to be unpalatable.* • Chocolate is not likely to replace BP meds any time soon. *Dark chocolate or tomato extract for prehypertension: a randomised controlled trial Ried, et.al BMC Complementary and Alternative Medicine 2009, 9:22