Meiosis & Modern Genetics Name: ________________________________________ Date: ______ Period: _____ I. Meiosis (Chap 8, Sec 3) A. Meiosis is the process of making ________________ _______________ (gametes) which contain __________ the normal number of genetic material = haploid cells(n) B. What is the difference between diploid and haploid numbers of chromosomes? C. In your body which types of cells are diploid and which are haploid? D. Match the terms with their definition. _____ allele _____ gene _____ homologous chromosomes _____ autosomes _____ sex chromosomes _____ gametes A. B. C. D. Sex cells of the body like sperm and egg Different forms of a gene (ex: black vs. blonde hair) Chromosomes with genes in the same order but with different alleles A hereditary unit consisting of a sequence of DNA that occupies a specific location on a chromosome and determines a particular characteristic in an organism. E. Chromosomes that determine an organisms sex (XX in ♀ and XY in ♂) F. Chromosomes NOT involved in sex determination E. Diagram the stages of meiosis I with 1 chromosome. Use dots for the paternal chromosome and shaded for the maternal chromosome. Prophase I MetaphaseI Anaphase I Telophase I Cytokinesis -each homologous chromosome moves to an opposite pole of the dividing cells -**random separation of homologous chromosomes -chromosomes reach opposite ends of the cell -nucleus reforms around chromosomes of new cells –spindle fibers disassemble -cell is still 2n -cytoplasm divides between two cells Description Diagram Interphase -chromosomes replicate -two genetically identical chromatids -DNA coils -spindle fibers/centrioles appear -nucleus disassembles -homologous chromosomes pair up & exchange genes* -tetrads line up randomly along midline of cell -spindle fibers from the opposite pole attach to chromosomes F. *The pairing of homologous chromosomes during prophase I is called synapsis. Diagram a pair of homologous chromosomes undergoing synapsis and then crossing over. Label the tetrad & crossing over (pg 161-162) Define crossing over: Define genetic recombination: G. **Independent assortment of homologous chromosomes occurs during Anaphase I. What is independent assortment? H. Diagram the stages of meiosis II with 1 chromosome. Use chromosomes from meiosis I. Description Diagram Prophase II Metaphase II Anaphase II Telophase II Cytokinesis II -chromosomes reach opposite ends of the cell -nucleus reforms –spindle fibers disassemble -each of the four cells is 1n -cytoplasm divides -result is four new cells each with half the original cells # of chromosomes Meiosis II occurs in each cell formed during meiosis I. DNA is NOT copied before meiosis II. -DNA coils into chromosomes -spindle fibers/centrioles appear -nucleus disassembles -chromosomes line up in the midline of cell -spindle fibers from the opposite pole attach to chromosomes -chromosomes separate and move to opposite poles of the dividing cells II. Gamete formation & sexual reproduction (Chap 8, Sec 3) A. Compare and contrast spermatogenesis and oogenesis. Where do each occur? B. Are the gametes produced during meiosis the same genetically? Explain. C. Compare the development of the sperm and the egg in sexual reproduction. Specify which cells are diploid and which are haploid. Spermatogenesis Oogenesis Process: Process: D. What occurs during fertilization? E. Is the resulting zygote/embryo haploid or diploid. Explain. F. Which parent contributes more mitochondria to the new embryo explain your reasoning? G. Describe the differences between mitosis and meiosis? What is the end result of each process? H. What is nondisjunction? (pg 239) I. What is amniocentesis? (pg 245) J. What is chorionic villi sampling? (pg 246) III. Genetic Engineering (Chap 13, pg 266 -270) A. What is gene therapy? Gene therapy works best on what type of disorders? Give an example. B. Describe cloning by nuclear transfer. C. What is a genetically modified crop? (pg 269)