General notes for the exam and this study guide: 1. Anything in the reading is fair game for the exam even if not included in this study guide. So unless I have told you specifically that you can ignore something, please study everything in the book. However, I will of course draw the majority of my questions from topics I either stressed in lecture or in this study guide even if I include some questions from outside of these sources. So you should be strategic: make sure you know the material I stressed during lecture and here in the study guide first, then if you feel you understand that well enough, then turn to textbook to try to identify other potentially important topics left out. 2. For the key terms in these chapters a) The most important terms to know are in bold, then the next important are those in normal text (non-bolded), and the least important are in grey text. b) The crossed out terms are those that were bold in the book but that I don’t expect you to memorize for the exam. c) Terms that are not bolded/highlighted in the book but which I think are important are shown in italics. 3. For multiple choice questions on the exam, read the questions and ALL of the answers very carefully before choosing an answer. Most questions will be multiple choice. Too often students will select the first one that sounds correct but if they had read all of the answer choices, they would realize why their first choice was not really correct. 4. Remember, many of my questions will approach the concepts in these chapters from a different perspective than the way you have learned them. If you truly understand the concept, this should not be too difficult, but if you just memorized an association between related terms or concepts, you will likely get confused and you will be more likely to choose an incorrect answer. 5. If I think of any other tips I will post them, but I want to get this out to you ASAP. Chapter 1 - Introduction: Biology Today Key Terms biology biosphere controlled experiment discovery science eukaryotic cell ecosystem genes genome hypothesis hypothesis-driven science life natural selection prokaryotic cell science scientific method theory Biology and Society: Biology All Around Us 6. Describe three examples of how biology is woven into the fabric of society. The Scope of Life 7. Read but don’t memorize the seven properties or processes we associate with life. Understand at least 3 of those well enough to explain to a friend how they are associated with life. 8. List in order of increasing complexity and give an example of each level of biological organization, starting with atoms and ending biosphere. a) The only one not covered either in this chapter (book or lecture), or other chapters covered since, is communities. (1) The difference between communities and populations is that populations are composed of a single species living in a particular area and communities are composed of many different species living in a particular area (2) The difference between communities and ecosystems is that an ecosystem includes nonliving components that life interacts with. 9. Describe the two main dynamic processes in an ecosystem. Within the ecosystem where can energy become trapped (even if only temporarily)? a) Describe the categories of organisms that are required for the “circle of life,” what they do, and a specific example of each 10. What is the smallest structure that can still be considered alive. 11. Compare the structure of prokaryotic and eukaryotic cells. 12. List each of the biological domains and which type of cells is associated with each one. 13. List and give one example of a specific organism for each of the subdivisions of domain eukarya (3 kingdoms and another group with multiple kingdoms). a) For the example for the group with multiple kingdoms, use one of the organisms we observed in lab. 14. Understand what is meant by “unity in the diversity of life” a) What are properties that unite all living things? b) What are properties that unite us with an amoeba but differentiate us from bacteria? c) What are properties that unite us with plants but differentiate us from amoebas? d) What are properties that unite us with all animals but differentiate us from plants? Evolution: Biology’s Unifying Theme 15. Understand how to interpret a “tree of life” as in fig 1.10. a) Name all of the closest relatives to the sun bear. b) Name which bear or bears is the most distantly related to the sun bear 16. Be able to write down the name of the famous scientist and the book that he published that had the most significant impact on our modern understanding of evolution. 17. What phrase from Darwin’s writings illustrate the duality of life’s unity and diversity? 18. Describe the two observations that led Darwin to his inescapable conclusion. State this conclusion. 19. Compare artificial and natural selection, noting similarities and differences. Give an example of each that was mentioned in lecture and/or the book. 20. Describe how broccoli arose from the wild mustard plant, be as specific as possible. Note that this requires you to “fill in the gaps” between what was covered in the book and lecture. The Process of Science 21. Compare discovery science and hypothesis-driven science. Provide examples of each regarding the study of trans fats in the human diet. 22. Distinguish between a hypothesis and a theory. Explain why natural selection qualifies as a scientific theory. 23. Distinguish science from other styles of inquiry. 24. Explain why being wrongly imprisoned for 25 years makes the man in fig 1.18 so happy. ;-) …this will not be on the exam! Evolution Connection: Evolution in Our Everyday Lives 25. Describe the relationship between the emergence of antibiotic resistance in bacteria and natural selection. How is this different than what Lamark (from chapter 13) would say? Chapter 2 - Essential Chemistry for Biology Key Terms acid aqueous solution atom atomic number base buffers chemical bonds chemical reactions cohesion compounds covalent bond electron elements evaporative cooling heat hydrogen bonds ions ionic bond isotopes mass mass number matter molecule neutron nucleus pH scale polar molecule products proton radioactive isotope reactants solute solution solvent temperature trace elements Biology and Society: More Precious than Gold 1. Explain why water is precious to life. Some Basic Chemistry 2. Distinguish between matter, chemical elements, and compounds. Give examples of each. 3. Describe the relative size, location, and electrical charge of protons, neutrons, and electrons within an atom. Explain how the atomic number and mass number are determined. 4. A neutral\balanced carbon atom has 6 protons, 6 neutrons and 6 electrons, what could you do to the atom to create: a) A different element b) A different isotope c) An ion of the same element 5. Explain how the location of electrons determines the chemical properties of an atom. 6. Distinguish between ionic, covalent, and hydrogen chemical bonds. 7. Water is a polar molecule, what does this mean? What is it about the molecule that creates the polarity? Water and Life 8. Describe the four life-supporting properties of water. 9. Distinguish between the chemical properties of acids, bases, and neutral solutions. Evolution Connection: The Search for Extraterrestrial Life 10. Explain why the search for extraterrestrial life centers on the search for water. Chapter 3: The Molecules of Life Key Terms amino acid atherosclerosis carbohydrates cellulose dehydration reaction denaturation disaccharide DNA double helix fat functional groups gene glycogen hydrocarbons hydrogenation hydrolysis hydrophilic hydrophobic isomers lipids macromolecules monomers monosaccharides nucleic acids nucleotides organic compounds peptide bond polymers polypeptide polysaccharides primary structure protein RNA saturated secondary structure starch steroids sugar-phosphate backbone trans fat triglyceride unsaturated Biology and Society: Got Lactose? 1. Describe the causes and consequences of lactose intolerance. Organic Compounds 2. Describe the special bonding properties of carbon that allow it to form an endless variety of organic molecules. Large Biological Molecules 3. Briefly describe and give examples of the following: monosaccharides, disaccharides and polysaccharides in living organisms. 4. Lipids and carbohydrates have vastly different chemical properties, most carbohydrates tend to be ____________ whereas lipids are ______________. 5. Describe the structure of proteins. Distinguish between the primary structure and the final three-dimensional shape. 6. Describe and compare the structures of DNA and RNA. a) There is something missing in DNA that is present in RNA, on what part of the nucleotide is this missing? 7. What is a gene? Evolution Connection: Evolution and Lactose Intolerance in Humans 8. Don’t worry about the top box on pg 51: “Lactose Intolerance THE PROCESS OF SCIENCE” 9. Explain why lactose intolerance has evolved differently in humans spread throughout the world. Chapter 4 - A Tour of the Cell Key Terms cell junctions cell theory central vacuole chloroplasts chromatin chromosomes cilia cristae cytoplasm cytoskeleton cytosol electron microscope (EM) endomembrane system endoplasmic reticulum (ER) eukaryotic cells extracellular matrix flagella fluid mosaic Golgi apparatus grana light microscope (LM) lysosome magnification matrix microtubules mitochondria nuclear envelope nucleoid nucleolus nucleus organelles phospholipids phospholipid bilayer plasma membrane prokaryotic cells resolving power ribosomes rough ER scanning electron microscope (SEM) smooth ER stroma transmission electron microscope (TEM) transport vesicles vacuoles Biology and Society: Antibiotics: Drugs that Target Bacterial Cells 1. Explain how antibiotics specifically target bacteria while minimally harming the human host. The Microscopic World of Cells 2. Compare the following pairs of terms, noting the most significant differences: light microscopes versus electron microscopes, magnification versus resolution, prokaryotic cells versus eukaryotic cells, plant cells versus animal cells. Membrane Structure 3. Describe the structure of the plasma membrane and other membranes of the cell. 4. What is on the surface of most animals cells that connect cells together into tissues? The Nucleus and Ribosomes: Genetic Control of the Cell 5. I didn’t go over this in class, but know that the genetic information in DNA is copied into mRNA which leaves the nucleus. Ribosomes “read” the genetic information in the mRNA and translate the nucleic acid code into an amino acid sequence which folds in a specific way to produce a functional protein (see pg 63). The Endomembrane System: Manufacturing and Distributing Cellular Products 6. The endoplasmic reticulum occurs in two forms, what are these forms? a) In terms of how the two appear, what makes one form different than the other? Be specific. b) Which form is important for producing proteins that are secreted? 7. Which part of the endomembrane system serves as the “shipping and receiving” center? Chloroplasts and Mitochondria: Energy Conversion 8. The figure in the chapter summary on pg 72 is good, know the concepts underlying this figure 9. Don’t worry about the terms stroma, grana, cristae, and matrix (mitochondrial) you’ll have to wait until next week for those ;) 10. Compare the structure and function of chloroplasts and mitochondria. Describe the adaptive advantages of extensive folds in the grana of chloroplasts and the inner membrane of mitochondria. The Cytoskeleton: Cell Shape and Movement 11. Don’t worry about the definitions of, or the differences between, the different types of filaments (microtubules, intermediate filaments, and microfilimants) but DO KNOW the names of each and that each are part of the cytoskeleton 12. Describe the functions of the cytoskeleton. 13. Don’t worry about the similarities and differences between cilia and flagella, just know they are long thin structures that extend out from the cell membrane and move/wiggle. Evolution Connection: The Evolution of Antibiotic Resistance 14. Explain how and why antibiotic-resistant bacteria have evolved. Chapter 13 - How Populations Evolve Key Terms evolution evolutionary adaptation fossils natural selection population Charles Darwin and The Origin of Species 1. Compare the ideas of Aristotle, Lamarck, and Darwin on the ability of species to change. 2. Explain how Darwin’s voyages on the Beagle influenced the development of his thoughts on evolution. 3. Explain how Lyell’s ideas impacted Darwin’s thinking. 4. Describe Darwin’s two main points in The Origin of Species. Natural Selection 5. Describe Darwin’s two main observations that led to the concept of natural selection. 6. Explain how natural selection is more a process of editing than a creative mechanism. Chapter 21 - How Populations Evolve Key Terms connective tissue epithelial tissue muscle tissue nervous tissue organ organ systems tissue General 1. Don’t worry about the specific details of each of the figures on p 468-463 but still look over them. The Structural Organization of Animals 2. Understand what is meant by form fits function and the analogy with the screwdriver and hammer. Understand why this is an important concept in biology. 3. Define a tissue and describe the four main categories of animal tissues, noting examples of each. 4. Be able to define and differentiate between organelles, cells, tissues, organs, organ systems and organisms. Also be able to give an example of each (refer to earlier chapters for more)