Lab 10: Reproductive System Endocrine Review • What is the structure that transports hormones from the hypothalamus to the posterior pituitary gland? • What is the function of parathyroid hormone? Digestive Review • What 2 structures are linked by the esophagus? • Name two specialized structures in the digestive tract that increase the surface area available for reabsorption. Announcements • Next week- Final Lab Practical Review • Lab Reports Due Today • Final Lab Practical regular lab time two weeks from today. Sexual vs. Asexual Reproduction • What is sexual reproduction? • Compared to asexual reproduction – Advantages – Disadvantages Chromosomes and “n” • What is “n”? – Number of copies of each chromosome • Difference between “n” and chromosome number. – Humans have 23 pairs of chromosomes – Humans are 2n – Humans have a total of 46 chromosomes Gametes and Zygotes • Gametes – 1N sex cells – Product of meiosis • Zygote – 2N fusion of gametes – Product of fertilization Meiosis vs Mitosis • Meiosis – Reduction division – Sexual division and formation of gametes • Mitosis – Somatic cell division – Chromosome “n” number same in starting cell and end products Sex organs and characteristics • Primary Sex Organs • Secondary Sex Organs • Secondary Sex Characteristics Overview- Male Reproductive Anatomy • • • • • • • • • Testis Epididymis Vas Deferens Prostate Gland Seminal Vesicle Bulbourethral Gland Penis Urethra Glans Penis Male Reproductive System Scrotum • Testis – Produce Sperm • Epididymis – Stores Sperm and allows to mature • Vas deferens – Connects epididymis to the seminal vessicles – Smooth muscles transport sperm to pelvic cavity Semen • Semen: fluid ejaculated by the male • Components: – – – – Sperm: 10% of semen Prostrate Gland: 30% of semen Seminal vesicle: 60% of semen Secretions from the Bulbourethral gland • Secretes fluid that lubricates tip of penis • Neutralizes acid pH from urine Penis • Penis – Delivers semen to the vagina • Urethra – Tube that delivers semen out of body – What other system is this a part of??? • Glans penis – Swollen head of the penis Erection • Cause – Increase Blood Flow / Vasodilation • Activator – Sexual simulation – Nitric Oxide stimulates vasodilation Overview- Female Reproductive System • • • • • • Ovary Fimbriae Uterine tubes Uterus Cervix Vagina Female Reproductive System Uterine tubes Uterus Vagina Ovary Egg development and Transport • Ovary – Female gonads produce eggs • Fimbriae – Feathery projections connect ovary to the uterine tube • Uterine Tube – Delivers egg to the uterus Uterus • • • • • • Thick muscular chamber Fertilized egg will attach to wall Harbors embryo Provides nutrition to embryo Expels fetus 3 layers: perimetrium, myometrium and endometrium Birth Canal • Cervix – Cylindrical inferior end of Uterus • Vagina – Birth Canal – Receptor for the penis Dynamic Human CD Anatomy Spermatogenesis • Primordial Germ Cell Mitosis • Type A and Type B spermatogonium • Type A retained • Type B passes over blood-testis barrier and becomes Primary spermatocyte Spermatogenesis • Primary spermatocyte Meiosis I • Secondary spermatocyte Meiosis II • Spermatids Spermatogenesis • Spermatozoa Spermatogenesis Oogenesis • One cell type (Primary oocyte) 2n • Meiosis first division – Secondary Oocyte (1n) – Polar body 1n (Degrades) Secondary Oocyte • No fertilization – Gets half way through meiosis 2 and dies • Fertilization – Meiosis second division completes – Egg 1n (to be fertilized) – Polar body 1n (Degrades) Oogenesis Summary of Gamete Formation • Spermatogenesis – 1 primary spermatocyte produces 4 spermatozoa • Oogenesis – 1 primary oocyte produces 1 egg and two lost polar bodies Dynamic Human CD Spermatogenesis and Oogenesis Ovarian Cycle (Egg maturation) • Follicular – Lasts about 14 days – First 3-5 days menstruation – Developing oocytes held in follicle, polar bodies die • Ovulation – Day 14 – Oocyte released from follicle • Luteal – About 14 days – Oocyte held in corpus luteum Ovarian Cycle Menstrual Cycle • Proliferative – Rebuilding of endometrial tissue by mitosis • Secretory – Thickening of endometrial tissue caused by secretion of nutrient-rich fluid • Menstration – Blood, serous fluid and tissue discharge Menstrual Cycle Breast Cancer • Cancer of the lymphatic vessels of the breast • Caused by: – – – – Excess weight Smoking Alcohol Heredity • Treatment – Lumpectomy – Partial mastectomy – Total mastectomy Circumcision • Prepuce is removed from Glans penis • Done for hygienic reasons • Largely deemed unnecessary today – Although??? Sterilization Males • Vasectomy – Vas deferens severed Females • Tubal ligation – Division of uterine tubes Cat dissection • Sex the cat • Female – Ovary – Uterine horns – Body of uterus Male – Scrotum – Testes – Carefully remove the connective tissue surrounding the testes epididymis vas deferens - Penis Review • • • • Reproductive anatomy Meiosis and Gamete formation Identification of anatomy of cats Lab Practical Review Next Week during normal lab time. • Final Lab Practice two weeks from today