Name: Nationality: Fadel A. Sharif Palestinian Profession: Birth: Gaza Molecular Biologist Place of Present Employer: Birth: 1963 The Islamic University of Gaza Date of Field of Interest: Male Molecular Genetics Sex: Address: Islamic University of Gaza, Medical Technology Dept. Gaza Strip, P.O. Box 108. Tel: 08-2863554 ext. 2675. Fax: 08-2863552. Mobile: 0599-308364, E-mail: fsharif@iugaza.edu EDUCATION 2005 Professor in Molecular Biology, Islamic University-Gaza 1999 Associate Professorship in Biology, Ankara-Turkey 1991 Ph.D. in Biology, Middle East Technical University, Ankara-Turkey 1987 M.Sc. in Biology, Middle East Technical University, Ankara-Turkey 1985 B.Sc. in Biology, Middle East Technical University, Ankara-Turkey EMPLOYMENT RECORD 2007-present IUG Lecturer/Researcher 2004-2006 Vice Dean 2005 IUG Professor Medical Technology Department, Faculty of Science, IUG Medical Technology Department, 1999-2004 Associate Professor 1999- 2003 IUG. Chairperson 1996-1998 Assistant Professor 1995-1996 Unit Director Cooperation, Gaza. 1994-1995 Assistant Professor University. 1992-1994 Lecturer Ankara-Turkey. “ “ Researcher METU, Ankara-Turkey. 1986-1991 Research Assistant Ankara-Turkey. Medical Technology Department, IUG. Medical Technology Deapartment, Medical Technology Department, IUG. Ministry of Planning & International Institute of Pediatric Hematology, Hacettepe Department of Biological Sciences, METU, Biotechnology Research Center, Department of Biological Sciences, METU, EXPERIENCE RECORD 2006-present Director of Molecular Genetics Lab., Islamic University of Gaza 2005-present Supervisor in Biological Sciences Master Program, Islamic University of Gaza. Lecturer in “Applications of Molecular Genetics in Medicine” and Biological Sciences Master 2004-present “Microbial Genetics”, Program, Islamic University of Gaza. Co-supervisor of an M.Sc. thesis entitled “Prevalence of Escherichia 2002-2003 coli O157:H7 and other microbial parameters in Gaza Strip” Ein Shams & Al-Aqsa Univ. program 1996- present Lecturer in “Medical Genetics”, “Virology”, “General and Environmental Microbiology”, Medical Technology Dept., Islamic University of Gaza. 1995-1996 Unit director, Environmental Planning Directorate, Ministry of 19941995 19921994 19911994 19861991 Planning & International Cooperation , Gaza. Lecturer in Genetics, Hacettepe University, Pediatric Hematology Dept. (Turkey, Ankara) Lecturer in General Biology, Microbiology and Virology courses, METU Researcher in the Biotechnology Center on Rhizobia symbiosis and Biodegradation of xenobiotics (METU, Ankara) Research Assistant in General Biology, Biochemistry and Genetics, METU. PUBLICATIONS 2010. Dawoud M, Shubair ME, Sharif FA. RHD Gene Polymorphism among Palestinians of Gaza Strip. Annals of Alquds Medicine (Accepted for publication) 2010. Zaharna MM, Abed AA, Sharif FA. Calpain 10 Gene Polymorphism in Type 2 Diabetes Mellitus Patients in Gaza Strip. Medical Principles and Practice; (Accepted for publication). 2010. Al-Sallout RJ, Sharif FA. Polymorphisms in NOS3, ACE and PAI-1 genes and risk of spontaneous recurrent miscarriage in the Gaza Strip. Medical Principles and Practice; 19:99-104 (DOI: 10.1159/000273067) 2009. Abu Halima MS, Bernal LP, Sharif FA. Genetic variation of 15 autosomal short tandem repeat (STR) loci in the Palestinian population of Gaza Strip. Legal Medicine; 11:203–204. 2009. Alghorra S, Aljeesh Y, Sharif FA. Relation between Brain Natriuretic Peptide (BNP) and Congestive Heart Failure among Hypertensive Patients in Gaza Strip. Annals of Alquds Medicine. 5:1-8. 2009. Shaqalaih AJ, Abu Halima MS, Ashour MJ, Sharif FA. Screening for YChromosome Microdeletions in a Population of Infertile Males in the Gaza Strip. Journal of Experimental and Clinical Assisted Reproduction; 1-9. 2009 Abu-Eid SI; Gharbieh AM; Abed A; Sharif FA. CYP2C19 genotypes in a population of healthy volunteers and in children with hematological malignancies in Gaza strip. Canadian J. of Clinical Pharmacology; 16(1):e156-e162. 2008 El Qouqa IA, Shubair ME, Al Jarousha A, Sharif FA. Prevalence of Chlamydia trachomatis among women attending gynecology and infertility clinics in Gaza, Palestine. International Journal of Infectious Diseases DOI: 10.1016/j.ijid.2008.07.013. 2008 N.S. Abu Hujier and F.A. Sharif. Detection of methicillin-resistant Staphylococcus aureus in nosocomial infections in Gaza Strip. African Journal of Microbiology Research, 2:235-241. 2008 Abd Rabou F; Yassin M; Sharif FA; Al-Agha MR; Abu Daher K; Ali A; Hamad D. habitants’ Knowledge on Mosquito Proliferation and Control in the Wetland Ecosystem of Wadi Gaza, Gaza Strip, Palestine. Journal of the Islamic University of Gaza 2008; 16(2):41-61. 2008. Fadel A. Nassar, Farid H Abu-Elamreen, Mohammad E. Shubair, Fadel A Sharif. Detection of Chlamydia trachomatis and Mycoplasma hominis, genitalium and Ureaplasma urealyticum by Polymerase Chain Reaction in patients with sterile pyuria. Advances in Medical Sciences. Volume 53. 2008 Farid H Abu Elamreen, Abdalla A Abed, Fadel A Sharif . Viral, Bacterial and Parasitic Etiology of Pediatric Diarrhea in Gaza, Palestine. Medical Principles and Practice 17:296–301 2007 Farid H. Abu Elamreen, Abdala Aabed, Fadel A. Sharif. Detection and Identification of Bacterial Enteropathogens by Polymerase Chain Reaction (PCR) and Conventional Techniques in Childhood Acute Gastroenteritis in Gaza, Palestine. International Journal of Infectious Diseases. 11, 501—507. 2007 Farid H. Abu Elamreen , Fadel A. Sharif , Jamal Elshikh Deeb. Isolation and antibiotic susceptibility of Salmonella and Shigella strains isolated from children in Gaza, Palestine from 1999 to 2006. Journal of gastroenterology & hepatology, 23(8):e330-e333. 2006 Farid H. Abu Elamreen, Abdala Aabed, Fadel A. Sharif . Rotavirus Infection in Infants and Young Children with Acute Gastroenteritis in Gaza, Palestine. Annals of Alquds Medicine 2:11-17 2005. Sharif F.A., Yilmaz Y., Zieske A. and Qumsiyeh M.B. Natural Killer Cell lymphoma/Leukemia with homozygous loss of p27/kip1. Leukemia and Lymphoma Journal, accepted for publication. 2005. Hindi A, Shubair M, Sharif, F.A., Abed A. Entamoeba histolytica or Entamoeba dispar? Egyptian Journal of Parasitology. 2004. Sharif F.A. and Astal Z. Role of plasmids in mediating antibiotic resistance and extended-spectrum beta-lactamase production in Escherichia coli. Journal of the Islamic University of Gaza 2004; 12(2):1-8. 2004. Sharif F.A. and Arafa H.Z. Occurrence of Escherichia coli O157 in Gaza Strip: A preliminary study. Journal of the Islamic University of Gaza 2004; 12(1):51-56. 2004. Astal Z., Sharif F.A., Abdallah S., Fahd M. Extended spectrum beta-lactamase in E. coli isolated from community-acquired urinary tract infections in Gaza Strip, Palestine. Annals of Saudi Medicine 2004; 24(1):55-57 2003. Sharif F.A. Impact of a wastewater treatment facility on wells water in Beit Lahia, Gaza Strip. Journal of the Islamic University of Gaza 2003; 11(1):99-111. 2002. Astal Z., El-Manama A. and Sharif, F.A. Antibiotic resistance of bacteria associated with community-acquired urinary tract infections in the southern area of Gaza Strip. Journal of Chemotherapy (2002) 14: 259-264. 2002. Astal Z.Y. and Sharif F.A. Relationship between demographic characteristics and commuity-acquired urinary tractinfections. Eastern Mediterranean Health Journal 2002; 8(1):164-171. 2002. Sharif F.A. Prevalence and seasonal fluctuations of common intestinal parasites in Khan Younes, 1996-2000. Journal of the Islamic University of Gaza 2002; 10(2):69-79. 2002. Astal Z., Sharif F.A., Abdallah S., Fahd M. Multiresistant E. coli isolated from women with community-acquired urinary tract infections in Gaza Strip. Journal of Chemotherapy 2002; 14(6):637-638. 2002. Zabut B.M. Sharif F.A. Bashiti T. Photoproduction of hydrogen by Rhodobacter sphaeroides O.U.001 in a column photoreactor: effect of Halobacterium halobium. Journal of the Islamic University of Gaza 2002; 10(1):21-32. 2001. Sharif F.A. and Zabut B.M. Glucose oxidase production by Cladosporium, Alternaria and Aspergillus isolated from stored grains. Al-Aqsa University Journal 2001; 5(2):9-16. 2001. Shubair M.E. and Sharif F.A. Lecture notes on virology: for students of medicine, pharmacy, medical technology and biology. 1st edition. Islamic University Publications, 2001. 1995. Sharif, F.A., Alaeddinoglu, N.G., Gene cloning and protoplast transformation in Aspergillus niger. (Review). DOGA: Turkish Journal of Biology (1995) 209-215 1995. Asgari, N., Sharif, F.A., Bacterial utilization of purified Temik aldicarb. Process Biochem. 30: 183-187. 1993. Arica, M.Y., Sharif, F.A., Alaeddinoglu, N.G., Hasirci, N., Covalent immobilization of Aspergillus niger on pHEMA membrane: application to continuous flow reactor. J. Chem. Tech. Biotechnol. 58: 281-285. 1993. Alaeddinoglu, N.G., Ozbakan, M., Ozkan, S., Sharif F.A. Science for high school students. Publications of Ministry of Education. Ankara (in Turkish language). 1992. Sharif, F.A. & Alaeddinoglu N.G. Expression and overproduction of glucose oxidase gene in Aspergillus niger. Appl. Microbiol. Biotechnol. 38:115-116. 1991. Sharif, F.A. Cloning and expression of glucose oxidase gene from Aspergillus niger NRRL-3. Ph.D. thesis, METU-Ankara. 1989. Kriechbaum, M., Heilmann, H.J., Weintijes, F.J., Hahn, M., Yany, K.D., Gassen, H.J., Sharif, F.A., Alaeddinoglu, N.G. Cloning and DNA sequence of glucose oxidase gene from Aspergillus niger NRRL-3. FEBS lett. 225: 63-66. 1988. Sharif, F.A. & Alaeddinoglu, N.G., A rapid and simple method for the staining of the crystal protein of Bacillus thuringiensis. J. Indust. Microbiol. 3:22-229. 1987. Sharif, F.A. Identification and genetical analysis of Bacillus thuringiensis plasmids. M.Sc. thesis, METU-Ankara. Thesis Supervised/co-supervised 8002Genetic Variation of 15 autosomal short tandem repeat (STR) loci in the Palestinian population of Gaza Strip 8002Polymorphism in NOS3, ACE and PAI-1 genes and risk of recurrent spontaneous miscarriage in Gaza strip 8002The Genetic Polymorphism of RhD among Blood Donors in Gaza strip and it is Reflection on Blood Transfusion Strategy 8002Community-acquired urinary tract infection causing microorganisms among paraplegic patients in Gaza strip Genetic causes of male infertility in Gaza strip-Palestine. A combined 8002cytogenetic and Y chromosome microdeletions study 8002Calpain 10 Gene Polymorphism in Type 2 Diabetes Mellitus Patients in Gaza Strip 8002 Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, and ureaplasma urealyticum in Palients with Sterile Pyuria in GazaPalestine 8002Detection of Chlamydia trachomatis in endocervical swabs using molecular (PCR) and enzyme immunoassay techniques 8002Application of Polymerase Chain Reaction Bacteriological Culture, Immunoassay, and Microscopy for Detection and Identification of Gastrointestinal Pathogens in Children, Gaza- Palestine 8002Association Between APOE Gene Polymorphism and Serum Lipid Profile in Coronary Heart Disease and Healthy Subjects 8002Detection of Methicillin- Resistant Staphylococcus aureus in nosocomial infection in Gaza Strip 8002Common CYP2C19 Alleles in Gaza Strip Population 8002CYP2C19 Polymorphism in Childhood Hematological Malignancy 8002Occurrence of Hereditary Hemochromatosis Among ? Thalassemia intermediate and ? Thalassemia minor subjects in Gaza strip- Palestine Brain natriuretic peptide (BNP) among congestive heart failure (CHF) 8002patients in Gaza strip 2000 Supervisor of an M.Sc. thesis entitled “Antibiotic resistance in community-acquired urinary tract infections among adults at Khan Younes hospital. Public Health Program, Al-Quds University. 2001-2003 Co-supervisor of a Ph.D. thesis entitled “Multiresistant Escherichia coli isolated from women with community-acquired urinary tract infections in Gaza Strip” Ein Shams & Al-Aqsa Univ. program. 1994 Co-supervisor of an M.Sc. thesis entitled “Characterization of Aldicarb Utilizing Bacteria” 1993 Co-supervisor of an M.Sc. thesis entitled “Microbial Utilization of Temik Aldicarb. PRESENTATIONS & OTHER PROFESSIONAL ACTIVITIES 2009. Zayed Harara, Abdalla A Abed, Fadel A Sharif. HFE gene mutations among ?thalassemia intermediate and ?-thalassemia minor individuals in Gaza strip, Palestine. Accepted for presentation. The 2nd international online conference on Medicine (IOMC 2009). 14-15 March, 2009. 2008. Fadel A. Sharif. Applications of molecular genetics in medicine. College of Medicine Conference (CMCI) Medical Education and Public health on 4-5 march 2008. 2008. Farid H. Abu Elamreen , Fadel A. Sharif, Jamal Elshikh Deeb. Isolation and antibiotic susceptibility of Salmonella and Shigella strains isolated from children in Gaza, Palestine from 1999 to 2006. College of Medicine Conference (CMCI) Medical Education and Public health on 4-5 march 2008. 2008. Ashraf Shaqalah, Fadel A. Sharif. Genetic causes of male infertility in Gaza strip-Palestine: A combined cytogenetic and Y chromosome microdeletion study. College of Medicine Conference (CMCI) Medical Education and Public health on 4-5 march 2008. 2007. Farid H. Abu Elamreen, Abdala Aabed, Fadel A. Sharif. Parasitic and viral infection in Infants and Young Children with Acute Gastroenteritis in Gaza, Palestine . 11th Annual Scientific Conference 2007 (11th ASCON 2007) 4-6 March 2007 at ICDDR, B. 2007. Fadel A. Sharif, Mohammad E. Shubair, Farid H. Abu Elamreen and Fadel Nassar. Detection of Chlamydia trachomatis and Mycoplasma spp in patients with sterile pyuria in Gaza, Palestine, Second Intentional Conference for science and development, Islamic University of Gaza (March 2007). 2007. Said Ghorra, Yousef Aljeesh, and Fadel A. Sharif. Relationship between duration time of systemic arterial hypertension and plasma brain natriuretic peptide, Second Intentional Conference for science and development, Islamic University of Gaza (March 2007). 2006. Farid H. Abu Elamreen, Abdala Aabed, Fadel A. Sharif . Detection and Identification of Bacterial Enteropathogens by Polymerase Chain Reaction (PCR) and Conventional Techniques in Childhood Acute Gastroenteritis in Gaza, Palestine. The 3rd International Conference on Child Health, Suadi Pediatric Association. November 2006 Jeddah Saudi Arabia 2006. Farid H. Abu Elamreen, Abdala Aabed, Fadel A. Sharif . Occurrence of Rotavirus in Infants and Young Children with Acute Gastroenteritis in Gaza, Palestine. The First Intentional Conference of Natural and Applied Sciences. Al-Aqsa University Faculty of Applied Science. 29-30 (2006) 2001-2002. Consultant in “UNDP-GEF-SGP funded biogas production from waste” project, IUG. 2000. Project coordinator in “Environmental awareness for school teachers”, IUG. 1994. Halicigil, C., Sharif, F.A., Ozden, M.Y., and Alaeddinoglu, N.G., Biotransformation of Aldicarb. Meeting Abstracts pp. 25. Presented at the 2nd National congress of Biotechnology. 1994. Ucgen. B., Erdal, E., Ozcengiz, G., Sharif, F.A., Rhizobium cicer-Chickpea symbiosis: Evaluation of some parameters. Meeting Abstracts pp. 21. Presented at the 2nd National Congress of Biotechnology. 1994. Erdal, E., Ozcengiz, G., Sharif, F.A., Genetical analysis of melanin production in Rhizobium cicer. Meeting Abstracts pp. 34. Presented at the 2nd National congress of Biotechnology. 1994. Sharif, F.A., Halicigil, C. Ozden, M.Y. and Alaeddinoglu, N.G. Biotransformation of Aldicarb. Meeting Abstracts pp.530. Presented at the 7th International congress of Bacteriol. and Appl. Microbiol. Prague, Czech Republic. 1994. Ucgen. B., Erdal, E., Ozcengiz, G., Sharif, F.A., Chickpea Rhizobium cicer symbiosis: Competitiveness of inoculants and optimization of nodulation conditions. Meeting Abstracts pp.547. Presented at the 7th International congress of Bacteriol. and Appl. Microbiol. Prague, Czech Republic. 1994. Erdal, E., Ucgen, b., Ozcengiz, G., Sharif, F.A., Chickpea Rhizobium cicer symbiosis: screening and characterization of effective strains. Meeting Abstracts, pp. 547. Presented at the 7th International congress of Bacteriol. and Appl. Microbiol. Prague, Czech Republic. 1993. Erdal, E., Ucgen, B., Sharif, F.A., Improvement of chickpea yields by various strains of Rhizobium cicer. Kukem Journal 16 (2): 122-123. Presented at the 8th Congress of Kukem. 1993. Ucgen B., Erdal, E., Sharif, F.A. Antibiotic resistance and plasmid analysis of local isolates of Rhizobium cicer. Kukem Journal 16 (2): 106-107. Presented at the 8th Congress of Kukem. 1993. Asgari, N., Sharif, F.A., Ozden, M.Y., Alaeddinoglu, N.G. Biodegradation of Temik aldicarb. Kukem Journal 16 (2): 26-27. Presented at the 8th Congress of Kukem. 1993. Arica, M.Y., Sharif, F.A., Alaeddinoglu, N.G. Genetical improvement of production of glucose oxidase from Aspergillus niger, immoblization and bioreactor application of the improved strain Kukem Journal 16 (2): 4-5. Presented at the 8th Congress of Kukem. 1993. Aygun, S.B., Sharif, F.A. Isolation and improvement of bacterial strains with degradative potential against 4-monochlorophenoxyacetic acid and 1,2dichloroethane. Presented at the 12th international meeting of the European Culture Collection Organization. 1993. Sharif, F.A. Arica, M.Y., Alaeddinoglu, N.G. and Hasirci, V. Overproduction of glucose oxidase from Aspergillus niger and immobilization of overproducer and wild-type strains. Presented at the 12th international meeting of the European Culture Collection Organization. 1993. Sharif, F.A. and Alaeddinoglu, N.G. Cloning of glucose oxidase gene from Aspergillus niger. Presented at the 12th international meeting of the European Culture Collection Organization. 1993. Asgari, N., Ozden, M.Y., Sharif, F.A., Alaeddinoglu, N.G. Microbial degradation of Temik aldicarb. presented at the 12th international meeting of the European Culture Collection Organization. 1989. Sharif, F.A., Kocabiyik, S., Alaeddinoglu, N.G. Isolation of glucose oxidase producing fungi and mutagenesis for obtaining non-producing strains. J. Biochem. 14(3):183. Meeting abstract The Turkish Biochemical Society. 1987. Sharif, F.A., and Alaeddinoglu, N.G., Identification and genetical Analysis of Bacillus thuringiensis plasmids. J. Biochem. 12 (2): 96. Meeting Abstract, Turkish Biochemical Society 1987. Alaeddinoglu, N.G. and Sharif, F.A. A rapid and simple method for staining the crystal protein of Bacillus thuringiensis. Kukem Journal 10 (2): 40, 5th Congress of Kukem. Courses and Meetings Attended 1996, “Globe 96”, International Trade Fair and Conference, Globe Foundation of Canada. March 26-29, 1996. Vancouver, Canada. 1995, Environmental and Infrastructural Projects. September 3-9. Amesterdam, Holland. 1995, Integrated Coastal Zone Management. October 15-18. World Bank, Gaza. 1995, Coastal Zone Management in the Mediterranean. October 22-27. Tarragona, Spain. 1995, Second Regional Meeting of the Center for Environmental and Development for Arab Region and Europe. December 11-17. Cairo, Egypt. 1995, Tumor Biology Course, European School of Oncology. April 17-21. Antalya, Turkey. 1995, Cell Separation and Flow Cytometry. June 11-17. Prague, Czech Republic. 1995, Our Shared Environment. Israel/Palestinan Center for Research and Information. December, 18-20. Jerusalem. 1996, Improved Management of Programs. A course delivered by the Netherlands Management for Development Foundation. January 7-17. Gaza. 1996, The Ecosystem of the Gulf of Aqaba. February 22-25. Eilat. 1996, Beach and Sea Water Quality. Practical Training Course. January 27-31. The Islamic University-Gaza. MEMBERSHIPS Palestinian Academy of Science and Technology Turkish Society of Biotechnology FELLOWSHIPS 2003-2004 Fulbright Scholarship: Yale University, School of Medicine, Cytogenetics Unit 1988-1989 der Germany: Training in Gene Technology, Institute fur Biochemie Technischen Hochschule, Darmstadt. COMMUNITY SERVICE 2006-present Director of Molecular Genetics Lab. Islamic University of Gaza. 1999-2001 Vice-Director of the Continuing Education and Community Service Unit, IUG.