Enzymes What is an enzyme? • Organic catalyst • Protein molecule What is the function of an enzyme? Speed up chemical reactions by lowering the activation energy Activation Energy • energy required to start all chemical reaction • How can all reactions require energy, if some are considered exergonic/exothermic? Induced-Fit Model Factors that affect enzyme functioning 1. 2. 3. 4. 5. 6. Temperature pH Enzyme concentration Substrate concentration Cofactors/coenzymes inhibitors Cofactors/Coenzymes Feedback Inhibition • End product controls action of enzyme • When end product binds to enzyme, there is a change of shape and enzyme no longer functions