A/P 242 G. Brady 2013-2014 Somatotrophs (Acidophil) hGH Growth General body Building, Tissue repair Corticotrophs (Basophil) ACTH, MSH Anterior Pituitary Gland Cell Type Lactotrophs Thyrotrophs (Acidophil) (Basophil) Hormone Produced PRL TSH Result Of Activity ACTH Women Production Secrete Androgens Milk of T3, T4 (mainly DHEA) Production Secrete Men Glucocorticoids Unknown (mainly cortisol) MSH Produce Melanin (Skin Pigment) Gonadotrophs LH Surge for Ovulation (Basophil) FSH, FSH, LH FSH Produce estrogen, Initiate Follicle Development & Spermatogenesis FSH & LH Maturation of the follicle in ovary LH Ovulation, Produce Progesterone, Produce Testosterone Thyroid Gland Cell Type Follicular cells Parafollicular cells (“C” cells) Hormone Produced T3, T4 Calcitonin Result Of Activity Growth & Development Regulate metabolism, Nervous system reactivity Blood Ca++ by using the Ca++ to build bones by osteoblasts Parathyroid Gland Cell Type Principal or Chief cells Oxyphil Cells Hormone Produced PTH Unknown Result Of Activity Demineralize bone to Increase Blood Ca++ Thymus Cell Type NO CELLS TYPES Hormone Produced Thymopoietin, Thymosin & others Result Of Activity Proliferation, maturation of T- Lymphocytes Skin Cell Type NO CELLS TYPES Hormone Produced Vitamin D Result Of Activity Convert Vitamin D to Calcitriol Pineal Gland Cell Type Pinealocytes Hormone Produced Melatonin Result Of Activity Affects diurnal clock Adrenal Gland Cell Type 1.Cortex a.Zona glomerulosa Mineralcorticoids (Aldosterone) H2O, Na++ reabsorption K+ secretion, Vasoconstriction Increase Blood Pressure 1.Cortex b.Zone fascocilata 1.Cortex c.Zona reticularis Hormone Produced Glucocorticoids Androgens (cortisol) ( DHEA) Result Of Activity Anti-inflammatory response provides resistance to stress by keeping blood in a “ready state” w/Gluconeogenesis & Protein Catabolism Axillary, pubic hair, prepubertal growth, post menopausal estrogen, Women’s sex drive, facial hair 2. Medulla (Chromaffin Cells) Epinephrine (adrenaline) Norepinephrine “Fight-or-flight” response Posterior Pituitary Gland Cell Type Hormones made in hypothalmus are stored here Hormone Produced ADH Vasoconstriction Increase H2O reabsorption Oxytocin Result Of Activity “Let down” of Milk, inc. Uterine Contractions Ovaries 1.Follicle Cells Estrogen 2. Follicle Estrogen Blood Cholesterol Produce Sex Characteristics, initiate follicle development Cell Type 3. Developing Follicle 4. Mature Follicle 5. Corpus Luteum Hormone Produced Estrogen Progesterone/Estrogen Inhibin Result Of Activity Follicle Maturation Ovulation, Prepare Enlarge Uterus for birth Implantation, canal Breast development Inhibit FSH Relaxin Maintain Uterus in a resting state Testes Spermatogonia (in Seminiferous Tubules) Cell Type Leydig’s Cells Hormone Produced Testosterone Initiate Spermatogenesis Result Of Activity Protein Synthesis Develop male sexual characteristics and maturation, Sex drive Sertoli Cells (Sustentacular cells) Produce Inhibin inhibit FSH to regulate Spermatogenesis Placenta Cell Type NO CELL TYPES HCG Estrogens Progesterone Maintain estrogen and progesterone production for pregnancy Hormone Produced Relaxin Result Of Activity Relax pubic symphasis, Dilate cervix during labor Hc Sommatomammotropin Prepare breasts for Lactation Pancreas Acinar cells 99% Pancreatic tissue Secretes enzymes Digestion of specific nutrients Islets of Langerhans Alpha cells Cell Type Islets of Langerhans beta cells Islets of Langerhans delta cells Glucagon Hormone Produced Insulin Somatostatin (Panacrine) Blood sugar by glycogenolysis gluconeogenesis Result Of Activity Blood sugar by getting inhibits relase of sugar into cells both glucagon & glycogenesis, lipogenesis, insulin Protein anabolism Islets of Langerhans F cells Pancreatic Polypeptide Inhibits Pancreatic digestive enzymes