Name: ______________________________________________________________________ Date: _______ DNA and Central Dogma Study Guide 5-1: DNA Structure 1. Draw and label a nucleotide. 2. What are the four bases found in DNA? 3. What are the base paring rules? 4. Describe the difference between purines and pyrimidines. 5. Identify which bases are purines and which are pyrimidines. 6. Name and describe the two type of bonds found in DNA. 7. What term is used to describe the shape of DNA? Why? Label 8-13 by using the image to the right. 8. 9. 10. 11. 12. 13. 14. Complete the table by estimating the percentages of each based on Chargaff’s rules. Bases DNA Sample #1 DNA Sample #2 Adenine Thymine Cytosine Guanine 30 % 17% 5-2: DNA Replication 15. Describe what semi conservative replication means. Draw an image to represent this. 16. Explain the three steps of DNA replication. Include the roles of helicase and DNA polymerase. a. b. c. 17. Write the complimentary DNA bases to the right. 10-4: Transcription 18. Define Transcription and state where it takes place. 19. What are three types of RNA and what are their functions a. b. c. 20. Transcribe this DNA strand: A – G – C – T – G – A – A – C – G – T – A ____________________________________________ RNA Nucleic Acid Sugar Bases Used Number of Strands Where can it be found in the cell. Picture 10-4: Translation 21. What does translation make and where does it occur? 22. Explain the three steps of translation. a. b. c. 23. Translate this piece of mRNA into amino acids UAA CAA GGA GCA UCC 24. Draw and label the Central Dogma Diagram. DNA