Microbiology – Chapter 2 BIOLOGICAL CHEMISTRY Do Now What is an atom? What is an element? What is the name of the table that keeps track of all the elements? Why do biologists study chemistry?? Chemical changes in _________ are essential to all life processes All _______ ________ are made of the same kinds of matter that make up non-living things If you learn how ________ in matter occur you will understand the _____ ___________ of organisms Elements Elements – ______ _________ that cannot be broken down chemically into simpler kinds of matter Of more than 100 elements fewer than 30 are important to _______ _______ More than ____% of the mass of living things is composed of combinations of just: _____, ______, _____ and ______ Elements ________ _________ – usually part of the element’s name or the Latin word for the element Organized into the _______ _______ of elements There are 118 elements, 94 are naturally occurring, the rest are synthetic (made in particle accelerators) Elements listed by increasing atomic number Columns – groups of elements with similar properties because of the number of electrons in their outer shell Rows - periods Atoms – basic units of matter -________ are the simplest particles of an element that retain all the ________ of that element -Atoms are so small that their true structure has not been observed -Models of the atom help us understand their structure enough to _______ how they will act in nature Atoms Structure – net electrical charge of _______ a. Protons (charge +) 1 AWU b. neutron (charge 0) 1 AWU c. electrons (charge -) .008 AWU AWU – atomic weight unit _________ – central mass of an atom, contains protons and neutrons Atoms _________ – high energy particles that move about the nucleus at high speeds in one of several different energy levels - Electrons in _______ energy levels have more energy than those in ______ energy levels - Each energy level can only hold a certain _________ of electrons - 1st energy level can hold ___ electrons -2nd energy level can hold ___ electrons - In most elements, the outer energy level is Atom Number of Protons? Atom animation of an atom Atomic number – the number of protons in the nucleus of the atom Atomic mass – the number of protons plus neutrons in the nucleus of the atom Isotopes _________ – A different form of an element which has the same number of protons and electrons, but has a different number of _________ Carbon (C): -atomic number is 6 - it has 6 protons -mass number is 12 – it has 6 protons and 6 neutrons -C14 – isotope that has 8 neutrons Hydrogen Isotopes Isotopes Radioisotopes – _________ element forms whose nuclei can undergo spontaneous change in which charged particles and radiant energy are released Atoms Activity Complete worksheet on atoms Finish for homework if not completed in class Do Now What is the positively charged particle in an atom called? What is the negatively charged particle in an atom called? What is the neutral particle in an atom called? What is an isotope? Compound 1. A pure substance made up of ____ __ _____ elements combined chemically 2. The properties of compound _______ from the elements it is composed of – H2O vs. H and O 3. The _________ of each kind of element are fixed – Water always H2O 4. Elements combine and form compounds to become more ________ 5. Elements are more stable when their outer electron shells are ________ Bonds Chemical bonds – forces that ____ two or more atoms a. Covalent bonds – ________ of electrons (water H2O) b. Ionic bonds – __________ of electrons (sodium chloride NaCl) Chemical Bond Animation Molecules A _________ is the simplest part of a substance that retains all of the _________ of that substance and that can exist in a ______ state Hydrogen gas (H2) Water (H2O) Matter Activity Complete “Composition of Matter” worksheet. Finish what you don’t complete for homework. Do Now What is a compound? What is a covalent bond? What is an ionic bond? 2. INORGANIC CHEMISTRY STUDY OF COMPOUNDS THAT DO NOT CONTAIN THE THREE ELEMENTS ____, _____, & ____ AT THE SAME TIME. CAN CONTAIN _____ OF THOSE THREE AND ANY OF OTHER ELEMENTS ORGANIC CHEMISTRY LIVING THINGS ________ GREATLY FROM NON-LIVING THINGS THERE MUST BE A BIG DIFFERENCE IN HOW THEY ARE CONSTRUCTED THEY ARE ACTUALLY CONSTRUCTED OF THE ________ MATERIALS THE ONLY DIFFERENCE IS IN HOW THEY ARE ___________ ALL BIOLOGY HAS A __________ BASIS 3. ORGANIC CHEMISTRY STUDY OF _______ COMPOUNDS - CHEMICAL BASIS FOR LIVING CELLS ALWAYS _____, _____, & ______ SOMETIMES NITROGEN & PHOSPHORUS USUALLY SMALL AMOUNTS OF METALS THERE ARE “FOUR” DIFFERENT CLASSES OF ORGANIC COMPOUNDS ______________ ______________ ______________ ______________ Carbohydrates Organic compounds of C, H and O Used as ________ _________ in cells Also found in several __________ structures such as bacterial capsules They are synthesized from water and carbon dioxide during _____________ Carbohydrates _____________ are the simplest carbohydrates They are the building blocks for the larger carbohydrates (_______________) Glucose, galactose and fructose are examples of isomers – they have the same chemical formula C6H12O6 But their structures and properties are different A. CARBOHYDRATES Glucose Represents the basic supply of ______________ in the world Half of the world’s __________ exists as glucose GLUCOSE – UNIVERSAL ENERGY Disaccharides ____________ sugars – composed of _______ monosaccharides held together by covalent bonds They are made from glucose molecules through ___________ __________– water is removed as the new bonds are formed Examples are: maltose – found in barley and used to ferment beer lactose – found in milk and digested by bacteria to form yogurt, sour cream Sucrose – table sugar and is the starting point in wine fermentation and may be a cause of tooth decay DISACCHARIDE – TWO MONOSACCHARIDES Polysaccharides ____________ sugars Large compounds formed by joining together 100’s or 1000’s of _________ molecules ___________ – used by bacteria as an energy source ___________ – a component of the cell walls of plants and molds and also used as an energy source by microorganisms Polysaccharide Polysaccharide animation Polysaccharides Activity Complete polysaccharides color worksheet Finish for homework if not completed in class Do Now What are the 4 classes of organic compounds? What 3 elements are carbohydrates made up of? What carbohydrate is considered a universal source of energy? B. LIPIDS __________ in organic solvents, but not in water Like carbohydrates, they are composed of C, H, and O, but with much less _________ The best known lipids are ________ Fats are important ___________ energy sources for living things Fats are also components of ______ ____________ LIPIDS cell membrane animation LIPIDS Fats consist of a 3 carbon ________ molecule and up to 3 long-chain ________ ________ 2 major types of fatty acids: ___________ – contain the maximum number of H atoms ___________ – contain less than the maximum number of H atoms Unsaturated fatty acids are good for us – they lower the levels of __________ in the blood LIPIDS Other types of lipids: ____________ – long chains of fatty acids Bee’s wax Plant leaves ____________ – contain a phosphate group Cell membranes ____________ – composed of several rings of carbon atoms with side chains Cholesterol Estrogen Testosterone C. PROTEINS Most __________ organic compounds of living things They can be: __________ __________ – regulate the rate of chemical reactions They are composed of chains of _______ _______ Each amino acid contains Carbon atom Amino group (NH2) Carboxyl group (COOH) Another side group Amino Acids – there are 20 Proteins Amino acids are joined together by __________ bonds The __________ of amino acids is extremely important One mistake changes the protein (____________) Protein Structure: Primary – AA sequence Secondary – AA chain twists into a corkscrew pattern Tertiary – Protein folds back upon itself Proteins Protein structure animation D. NUCLEIC ACIDS Some of the _______ molecules found in organisms ________ – genetic material of the chromosomes that carries the genetic code ________ – cell messenger that functions in protein construction Composed of __________ Carbohydrate molecule (ribose or deoxyribose) Phosphate group Nitrogenous base DNA – adenine, guanine, cytosine, thymine RNA – adenine, guanine, cytosine, uracil Nucleic Acids DNA is located in the ______________ of the cell It passes on the genetic information and directs _________ synthesis DNA molecule consists of 2 single strands of DNA in opposite directions arranged in a _________ _______ Nucleic acids can not be altered without disrupting or killing the organism – this can help us control ______________ DNA Structure Animation Acids and Bases Degree of ________ or _________ is very important to living systems You may hear the term pH a lot What does this mean? Acids and Bases Water can dissociate into: ____________ Ions OH- ____________ Ions H3O+ Acids and Bases - pH is a measure of a solution’s ___________ ion concentration -pH is a scale of _____ - _____ - an acid = more hydronium ions (H3O+) - a base = more hydroxide ions (OH-) Acids and Bases Acids : Have more hydronium ions Have a ________ taste In concentrated forms can be very ___________ Example: Strong acid – HCl (hydrochloric acid) Weak acid – CH3COOH (vinegar) Acid Rain Acids and Bases Bases : Have more _________ ions Have a ________ taste Tend to feel _________ because they react with the oil on our skin to form soap Example: Strong base – NaOH (sodium hydroxide) Weak base – NH4 (ammonia) Acids and Bases pH scale ranges from 0 – 14: Solution with a pH of 0 is very __________ Solution with a pH of 14 is very __________ Solution with a pH of 7 is __________ pH can be measured with pH paper or strips Acid Rain ______ ______is a rain or any other form of precipitation that is unusually _______ (low pH) It can have _________ effects on plants, aquatic animals, and infrastructure Acid rain is caused by _________ of compounds of ammonium, carbon, nitrogen, and sulfur which react with the _______ _________in the atmosphere to produce acids Formation results from both ________ sources (volcanoes, decaying vegetation) and ____________ sources (fossil fuel combustion) Activity Complete Acids/Bases worksheet Finish for homework if not completed in class