Ch. 10 Anatomy of the muscular system The incredible human machine QuickTime™ and a decompressor are needed to see this picture. Introduction • Myology - Study of muscles • Energy for Muscular contraction ATP • Three types of muscle - skeletal, cardiac, smooth • Number of skeletal muscles - more than 600 • Weight of muscles - 40-50% Full muscular system Connective Tissue coverings • Fascia - surrounds and separates muscles • Tendons - connects muscle to bone • Aponeurosis - broad sheet of connective tissue • Epimysium - covers whole muscle • Perimysium - covers fascicles • Endomysium - covers myofibrils Structure • Size - range from small to large • Shape -broad, narrow, short, long • Arrangement – Parallel, converging, oblique, pennate, bi- pennate, sphincter Attachment of muscles • Origin - attachment to immovable bone • Insertion - attachment to movable bone Muscle actions • Prime movers (agonists) - main action • Antagonists - opposite action • Synergists - helper muscle The power of muscle QuickTime™ and a decompressor are needed to see this picture. Lever systems • Bones serve as levers and joints serve as fulcrums • Contracting muscles applies pulling force on bone lever • Four components of lever system – – – – Rigid bar - bone Fulcrum - joint Load - what is moved Pull - muscle contraction How muscles are named • Latin based or English • Naming - supply hints as to muscle action – – – – – Location, function, shape Direction of fibers Number of heads Points of attachment Relative size Muscles of facial expression • Epicranius - raises eyebrows • Orbicularis oculi - closes eye • Orbicularis oris - draws lips together • Buccinator - smiling • Zygomaticus - laughing Muscles of mastication chewing • *Masseter - closes jaw • Temporalis - closes jaw Muscles that move the head • *Sternocleidomastoid - flexes head • *Splenius capitis - extends head • Semispinalis capitis - extends head Muscles of the thorax • *Intercostals - lift ribs • *Diaphragm - enlarges thorax Muscles that move the shoulder girdle • *Trapezius - raises shoulders • Rhomboideus major rotates/retracts scapula • Levator scapulae elevates/retracts scapula • Serratus anterior - pulls shoulder down and forward • *Pectoralis minor - pulls shoulder down Muscles that move the upper arm • Flexors – Coracobrachialis - adduction – *Pectoralis major - flex upper arm • Extensors – Teres major - extension, medial rotation – *Latissimus dorsi - extends upper arm • Abductors – Supraspinatus – *Deltoid • Rotators - *rotator cuff – Subscapularis- medial rotation – Infraspinatus - outward rotation – Teres minor - outward rotation Muscles that move the forearm • Flexors – *Biceps brachii – Brachialis – Brachioradialis • Extensor – *Triceps brachii Muscles that move the hand • Flexors – Flexor carpi radialis and ulnaris – Palmaris longus – *Flexor digitorum profundus • Extensors – – – – Extensor carpi radialis longus Extensor carpi radialis brevis Extensor carpi ulnaris *Extensor digitorum Muscles of the abdominal wall • *external and internal obliques compresses abdoment - allows for side to side motion • *Rectus abdominis • Flexes waist • Transverse abdominus synergist Compresses abdomen Muscles of the back • *Trapezius – Extends head/neck • *Rhomboideus – Retracts scapula • Infrapinatus – Extends/rotate arm • Teres major and minor – Extends, adduts arm • *Latissimus dorsi - extends – arm Muscles of the pelvic floor • Levator ani • Superficial transversus perinei • Bulbospongiosus • Ischiocavernoses Muscles that move the thigh • Anterior group – *Psoas major – Iliacus • Posterior group – *Gluteus maximus, medius, minimus – Tensor fasciae latae • Adductors – Adductor longus – Adductor magnus – Gracilis Muscles that move the leg • Flexors – *Biceps femoris – Semitendinosus – Sartorius • Extensor – *Quadriceps femoris group • Rectus femoris • Vastus lateralis/medialis/intermedius Muscles that move the ankle foot and toes • Dorsal flexors – *Tibialis anterior – Peroneus tertius – Exensor digitorum longus • Plantar flexors – *Gastrocnemius – Soleus (synergist) – Flexor digitorum longus Ch. 11 The physiology of the muscular system Introduction • Purpose - move framework of body, produce heat, facilitate posture • Characteristics – Excitability - ability to be stimulated – Contractibility - ability to shorten producing movement – Extensibility - ability to stretch and return to resting length. Structure of muscle fibers • Description - each fiber - muscle cell (spans a joint) • Sarcolemma - cell membrane • Sarcoplasm - cytoplasm of muscle cell – Contains mitochondria, nuclei, myofibrils • Myofibrils - filaments – Myosin - thick – Actin - thin • Sarcomere - unit within myofibril – Extends from z line to z line. – Z lines produce striations • Sarcoplasmic reticulum (endoplasmic reticulum) – Contains transverse tubules (nerve impulse) Neuromuscular Junction • Where neuron and muscle fiber meet. • Abundant mitochondria present for ATP production • Neurotransmitters - chemical communicators located at the end of neuron in the Cytoplasm • Motor Unit – Mucle fibers contract at once when triggered by neurotransmitters – Recruitment - increase in number of motor units activated. Skeletal Muscle Contraction • Shortening of sarcomeres results in muscle pulling against attachments – Myosin - two twisted strands with crossbridges – Actin contains myosin binding sites • Sliding filament theory – Myosin cross-bridge attaches to binding site on actin filament and bends – Pulls actin filament, releases and attaches to next binding site, pulling again. – Energy from atp used to prepare the crossbridges. Stimulus for contraction – Neurotransmitter - Acetylcholine released from synaptic vesicles at end of axon of neuron. • Note - botulinus toxin prevents acetylcholine release. – Receptors detect neurotransmitter – Impulse spreads over sarcolemma then travels through transverse to sarcoplasmic reticulum – Calcium released by sarcoplasmic reticulum – High calcium moves Troponin and tropomyosin aside, exposing binding site – Myosin Crossbridge attaches to binding site – Crossbridge shortens pulling filaments across each other – Sarcomere shortens – Acetylcholinesterase decomposes acetylcholine – Calcium returns to sarcoplasmic reticulum – Link between actin and myosin is broken. Muscle contraction QuickTime™ and a decompressor are needed to see this picture. Oxygen supply and cellular respiration • During rest - enough oxygen to support aerobic cellular respiration. • Oxygen deficiency during exercise – Lactic acid end product of anaerobic respiration. - lactic acid diffuses out of muscle cells and is carried to liver. • Oxygen debt - amount of oxygen that liver cells require to convert lactic acid into glucose plus amt. muscle cells need to make atp to original concentration. • Muscle fatigue-muscle loses ability to contract during strenuous exercise. • Result of lactic acid accumulation (lower ph) • Muscle cramp - lack of ATP required to return calcium ions back to sarcoplasmic reticulum so muscle fibers can relax. • Heat production - energy produced by cellular respiration is lost as heat. Muscular responses • One method of studying muscle function - remove single fiber and connect to device that records response to electrical stimuli. • Muscle fibers remain unresponsive till they reach Threshold stimulus (stimulus of a certain strength) • All or none response • Summation - series of stimuli of increasing frequency • Recruitment of motor units-increase in number of activated motor units • Sustained contractions - muscle tone - achieved by continuous state of sustained contraction. • Treppe-staircase phenomenon - twitch contractions 1 second apart • Tetanus-multiple wave summation/no relaxation Recording a muscular contraction • Myogram - recording of electrically stimulated muscle contraction • Myograph - machine that records the contraction • Twitch-single short contraction • Latent period - time delay followed by period of contraction and relaxation. Muscle tone • Tonic contraction-continual partial contraction of a muscle • Flaccid - less tone than normal • Spastic-more tone than normal • Negative feedback mechanism controls tone • Graded strength - affected by: – Metabolic condition of fibers – Number of fibers contracting – Number of motor units recruited Physical training • Strength training- results in hypertrophy enlargement of fibers • Endurance training - increases ability to sustain moderate contractions for longer time. Increase of mitochondria. • Atrophy - result of disuse – Decreased capillary networks, decreased mitochondria, decreased filaments. Smooth muscle • • • • • • Fibers - elongated with tapered ends Lack striations Undeveloped sarcoplasmic reticulum Located in iris of eye and walls of hollow organs Display rhythmicity - allow for peristalsis Contraction uses acetylcholine and norepinephrine • Slower to contract and relax but can contract longer Cardiac muscle • Mechanism - same as smooth and skeletal • Difference: transverse tubules supply extra calcium allowing for contraction for longer periods. • Structure – Intercalated discs - join cells and cause cells to contract as a unit. – Rythmic – Self-exciting