Paper DNA Replication Purpose: Procedure: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. Name: I can describe the structure of a DNA molecule I know base pairing rules I can diagram DNA replication Please follow the instructions as we replicate DNA at your tables. After your DNA has been replicated, please answer the following questions on the answer sheet you have been given. What are the three parts found in each DNA nucleotide? What type of sugar is found in each DNA nucleotide? What are the four nitrogen bases found in DNA? DNA is a polymer – what does that mean? Which base does adenine always pair with in a DNA molecule? Why does adenine always pair with THAT base, why not another? Which base does guanine always pair with? What is Chargraff’s rule? Which two bases are called purines? What structural characteristic do purines share? What two bases are called pyrimidines? What structural characteristic do pyrimidines share? What molecules make up the backbone of the DNA strand? What type of bond holds the two strands of DNA together? Are these bonds weak or strong? What type of bond holds one nucleotide to the next one down in the line in the DNA strand? Are these bonds weak or strong? Build a paper DNA molecule with the WHITE nucleotides! 18. What do you notice about the left side of your molecule compared to the right side of your molecule? 19. What characteristic of the real DNA molecule does your paper model not show? Replicate your DNA molecule using the GREEN nucleotides! 20. Which enzyme breaks the hydrogen bonds between the Nitrogen bases to get the molecule ready for replication? 21. When does DNA replication occur (specifically)? 22. Which enzyme builds the new strands of DNA by adding complimentary DNA nucleotides? 23. When DNA is replicated, there is a leading and lagging strand. Which strand is built continuously and which is built in fragments? 24. What are the fragments called? 25. Which enzyme binds the fragments together to make a continuous strand? 26. After replication, what is the next phase of the cell cycle? 27. Which enzyme proofreads the new DNA strands and makes corrections if necessary? Paper DNA Replication Name: Paper DNA Replication Name: 1._____________________________ _________________________________ _____________________________ 2.________________________________________________ 3. ____________________ _______________________ _______________________ _______________________ 4. ____________________________________________________________________________________________ 5. ______________________________________________ 6. ___________________________________________________________________________________________ 7. ______________________________________________ 8._____________________________________________________________________________________________ 9. _____________________________ ____________________________________ 10. ___________________________________________________________________________________________ 11. ____________________________ ____________________________________ 12. ___________________________________________________________________________________________ 13. _____________________________________________ _____________________________________________ 14. _____________________________________________ 15. ____________________ 16. _____________________________________________ 17. ____________________ 18.____________________________________________________________________________________________ 19. ___________________________________________________________________________________________ 20._____________________________________________ 21._____________________________________________ 22._____________________________________________ 23. ___________________________________________________________________________________________ 24. ____________________________________________ 25._____________________________________________ 26. ____________________________________________ 27._____________________________________________