Brains, Bodies, and Behavior Brains, Bodies, and Behavior • • • • The Neuron Is the Building Block of the Nervous System Our Brains Control Our Thinking, Feeling, and Behavior Psychologists Study the Brain Using Many Different Methods Putting It All Together: The Nervous System and the Endocrine System The Neuron Is the Building Block of the Nervous System The Neuron Is the Building Block of the Nervous System • Learning Objectives 1. Describe the structure and functions of the neuron 2. Draw a diagram of the pathways of communication within and between neurons. 3. List three of the major neurotransmitters and describe their functions. The Neuron Is the Building Block of the Nervous System Major Parts of a Neuron Soma (Cell Body) contains the cell’s nucleus keeps the cell alive Dendrite collects information from other cells sends the information to the soma Axon transmits information away from the cell body, toward other neurons or muscles and glands The Neuron Is the Building Block of the Nervous System • Specialized parts of an axon – myelin sheath – layer of fatty tissue surrounding the axon • insulates the axon • speeds the transmission of the electrical signal – terminal button – branching toward the end of an axon • Image of a motor neuron, with dendrite, axon and cell body labeled and described Neurons Communicate Using Electricity and Chemicals Within a Neuron • Communication is electrical, taking the form of a charge called an action potential Between Neurons • Communication is chemical, via neurotransmitters which travel across the gap between two neurons Neurons Communicate Using Electricity and Chemicals Resting Potential the interior of a neuron is negatively charged relative to the area outside the neuron Action Potential when an electrical signal is passed from the dendrites, the neuron’s charge changes from negative to positive Refractory Period following an action potential, a neuron cannot fire again for a brief time Neurons Communicate Using Electricity and Chemicals • The myelin sheath wraps around the axon, but also leaves small gaps called the Nodes of Ranvier. • The action potential jumps from node to node as it travels down the axon Neurotransmitters: The Body’s Chemical Messengers synapse • areas where the terminal buttons at the end of an axon nearly touch another neuron’s dendrites neurotransmitter • chemicals that relay signals across the synapses between neurons reuptake • neurotransmitters in the synapse are reabsorbed into the transmitting terminal buttons Neurotransmitters: The Body’s Chemical Messengers action potential reaches terminal button neurotransmitter release neurotransmitters bind to receptor sites on dendrite neurotransmitter reuptake neurotransmitters travel across synapse • • When the nerve impulse reaches the terminal button, it triggers the release of neuro-transmitters into the synapse. The neuro-transmitters fit into receptors on the receiving dendrites in the manner of a lock and key Neurotransmitters: The Body’s Chemical Messengers Excitatory neurotransmitters – increase the likelihood that a neuron will fire Inhibitory neurotransmitters – decrease the likelihood that a neuron will fire Agonist • Drug that mimics or enhances the influence of a given neurotransmitter – e.g., cocaine is a dopamine agonist Antagonist • Drug that blocks or inhibits the activity of a given neurotransmitter – e.g., curare is an acetylcholine antagonist Neurotransmitters: The Body’s Chemical Messengers Neurotransmitters: The Body’s Chemical Messengers The Neuron Is the Building Block of the Nervous System • Key Takeaways – The Central Nervous System (CNS) is the collection of neurons that make up the brain and the spinal cord. – The Peripheral Nervous System (PNS) is the collection of neurons that link the CNS to our skin, muscles, and glands. – Neurons are specialized cells, found in the nervous system, which transmit information. Neurons contain a dendrite, a soma, and an axon. The Neuron Is the Building Block of the Nervous System • Key Takeaways, continued – Some axons are covered with a fatty substance known as the myelin sheath which surrounds the axon acting as an insulator, allowing faster transmission of the electrical signal – The dendrite is a treelike extension that receives information from other neurons and transmits electrical stimulation to the soma. – The axon is an elongated fiber that transfers information from the soma to the terminal buttons. The Neuron Is the Building Block of the Nervous System • Key Takeaways, continued – Neurotransmitters relay information chemically from the terminal buttons and across the synapses to the receiving dendrites using a type of lock and key system. – The many different neurotransmitters work together to influence cognition, memory, and behavior. – Agonists are drugs that mimic the actions of neurotransmitters, whereas antagonists are drugs that block the action of neurotransmitters. Our Brains Control Our Thinking, Feeling, and Behavior Our Brains Control Our Thinking, Feeling, and Behavior Learning Objectives: 1. Describe the structures and function of the “old brain,” and its influence on behavior. 2. Explain the structure of the cerebral cortex (its hemispheres and lobes) and the function of each area of the cortex. 3. Define the concepts of brain plasticity, neurogenesis, and brain lateralization. Our Brains Control Our Thinking, Feeling, and Behavior • The “Old Brain” – Includes the brain structures nearest the spinal cord – Regulates basic survival functions, such as breathing, moving, resting, and feeding – Contributes to experiences of emotion • • In addition to the old brain, humans have a large and highly developed outer brain layer known as the cerebral cortex. The cortex provides humans with excellent memory, outstanding cognitive skills, and the ability to experience complex emotions. The Old Brain: Wired For Survival Brainstem includes the medulla, pons, and reticular formation thalamus filters sensory information from spinal cord; relays information to cortex cerebellum coordinates voluntary movement Limbic System includes the amygdala, hippocampus, and hypothalamus The Old Brain: Wired For Survival The Brainstem Medulla nearest the spinal cord controls heart rate and breathing Pons helps control movement; plays a major role in balance and walking Reticular Formation filters stimuli from spinal cord plays a role in eating, walking, sexual activity, and sleeping The Old Brain: Wired For Survival The Old Brain: Wired For Survival The Limbic System Amygdala regulates our perceptions of and reactions to aggression and fear Hippocampus helps store information in long-term memory Hypothalamus links the nervous system to the endocrine system via the pituitary gland helps regulate body temperature, thirst, hunger, and sexual motivation The Old Brain: Wired For Survival The Cerebral Cortex Creates Consciousness and Thinking • cerebral cortex – the outer, bark-like layer of the human brain that allows us to use language, acquire complex skills, create tools, and live in social groups – contralateral control – the left side of the cortex responds to and controls the right side of the body, and vice versa • • The brain is divided into two hemispheres - left and right. Each hemisphere has four lobes -temporal, frontal, occipital and parietal. The Cerebral Cortex Creates Consciousness and Thinking Frontal Lobes thinking, planning, memory, and judgment; contain motor cortex Parietal Lobes process touch information; contain somatosensory cortex Temporal Lobes Occipital Lobes hearing and language; contain auditory cortex process visual information and contain visual cortex The Cerebral Cortex Creates Consciousness and Thinking • • In addition to its motor and sensory areas, the cortex contains association areas. In the association areas, sensory and motor information is combined and related to our stored knowledge. The Brain is Flexible: Neuroplasticity • • neuroplasticity – the brain’s ability to change its structure and function in response to experience or damage neurogenesis – the forming of new neurons The Left and Right Hemispheres • Brain Lateralization – The left and right hemispheres are specialized to perform different functions. – The corpus callosum is a band of fibers connecting the two hemispheres. – Sperry’s research on split brain patients contributed to our understanding of brain lateralization. The Left and Right Hemispheres Left Hemisphere -- language -- mathematics -- judging time and rhythm --sequencing complex movements Corpus Callosum connects left and right hemispheres Right Hemisphere -- perceptual skills -- recognizing objects and faces -- recognizing patterns and melodies -- drawing pictures Our Brains Control Our Thinking, Feeling, and Behavior • Key Takeaways – The old brain, including the brainstem, medulla, pons, reticular formation, thalamus, cerebellum, amygdala, hypothalamus and hippocampus regulates basic survival functions such as breathing, moving, resting, feeding, emotions and memory. – The cerebral cortex, made up of billions of neurons and glial cells, is divided into the right and left hemispheres and into four lobes. – The frontal lobes are primarily responsible for thinking, planning, memory and judgment. The parietal lobes are primarily responsible for bodily sensations and touch. The temporal lobes are primarily responsible for hearing and language. The occipital lobes are primarily responsible for vision. Other areas of the cortex act as association areas, responsible for integrating information. Our Brains Control Our Thinking, Feeling, and Behavior • Key Takeaways, continued – The brain changes as a function of experience and potential damage in a process known as plasticity. The brain can generate new neurons through neurogenesis. – The motor cortex controls voluntary movements. Body parts requiring the most control and dexterity take up the most space on the motor cortex. – The sensory cortex receives and processes bodily sensations. Body parts that are the most sensitive occupy the greatest amount of space on the sensory cortex. – The left cerebral hemisphere is primarily responsible for language and speech in most people, whereas the right hemisphere specializes in spatial and perceptual skills, visualization, and the ability to recognize patterns, faces, and melodies. Our Brains Control Our Thinking, Feeling, and Behavior • Key Takeaways, continued – The severing of the corpus callosum, which connects the two hemispheres, creates a “split brain patient,” with the effect of creating two separate minds operating in one person. – Studies with split-brain patients as research participants have been used to study brain lateralization. – Neuroplasticity allows the brain to adapt and change as a function of experience or damage. Psychologists Study the Brain Using Many Different Methods Psychologists Study the Brain Using Many Different Methods • Learning Objective: 1. Compare and contrast the techniques that scientists use to view and understand brain structures and functions. Psychologists Study the Brain Using Many Different Methods • Cadaver Approach – The most direct approach to understanding the structure of the brain Advantage Disadvantage brain can be fully studied the brain is no longer active Lesions Provide a Picture of What is Missing • Lesions – In living humans, lesions are areas of brain damage resulting from accidents, strokes, gunshots, or other injuries. – Lesions may also be created intentionally in animals. – Lesions allow scientists to observe the loss of function that results. Lesions Provide a Picture of What is Missing • • • Areas in the frontal lobes of Phineas Gage were damaged when a metal rod was blasted through it. Gage’s personality, emotions, and moral reasoning were influenced. The accident helped scientists understand the role of the frontal lobes in these processes. Recording Electrical Activity in the Brain • • In animals, detectors can be placed in the brain to study the electrical activity caused by the firing of specific neurons. In living humans, the electrical activity of the brain’s neurons can be studied using scalp electrodes – this is electroencephalography, or EEG. Recording Electrical Activity in the Brain Advantages of EEG • • • Useful in understanding brain abnormalities such as epilepsy Participants can move around during recordings Allows changes to brain activity to be tracked very quickly Disadvantage of EEG • Does not provide a clear picture of the brain’s structure Peeking Inside the Brain: Neuroimaging • Functional Magnetic Resonance Imaging (fMRI) – a type of brain scan that uses a magnetic field to create images of the activity in each brain area – detects the blood flow in each brain region – currently the most common method of learning about brain structure Peeking Inside the Brain: Neuroimaging Advantages of fMRI Disadvantage of fMRI provides detailed pictures of brain structures scanners are expensive non-invasive Peeking Inside the Brain: Neuroimaging • Transcranial Magnetic Stimulation (TMS) – procedure in which magnetic pulses are applied to a living person’s brain to temporarily and safely deactivate a small brain area – allows cause-and-effect conclusions about the influence of brain structures on thought and behavior Psychologists Study the Brain Using Many Different Methods • Key Takeaways – Studying the brains of cadavers can lead to discoveries about brain structure, but are limited due to the fact that the brain is no longer active. – Lesion studies are informative about the effects of different brain regions. – Electrophysiological recording may be used in animals to directly measure brain activity. Psychologists Study the Brain Using Many Different Methods • Key Takeaways, continued – Measures of electrical activity in the brain, such as electroencephalography (EEG) are used to assess brainwave patterns and activity. – Functional Magnetic Resonance Imaging (fMRI) measures blood flow in the brain during different activities, providing information about the activity of neurons and thus the functions of brain regions. – Transcranial Magnetic Stimulation (TMS) is used to temporarily and safely deactivate a small brain region, with the goal of testing the causal effects of the deactivation on behavior. The Nervous System and The Endocrine System The Nervous System and The Endocrine System • Learning Objectives: 1. Summarize the primary functions of the CNS and of the subsystems of the PNS. 2. Explain how the electrical components of the nervous system and the chemical components of the endocrine system work together to influence behavior. Electrical Control of Behavior: The Nervous System • Nerves – bundles of interconnected neurons that fire in synchrony sensory (afferent) neurons carry information from the sensory receptors motor (efferent) neurons transmit information to the muscles and glands interneurons communicate information among neurons Electrical Control of Behavior: The Nervous System Central Nervous System Brain Spinal Cord Electrical Control of Behavior: The Nervous System • • Reflexes – involuntary, nearly instantaneous movements in response to stimuli Triggered when powerful sensory information allows spinal cord interneurons to send a message back through the motor neurons without relaying the information to the brain Electrical Control of Behavior: The Nervous System Peripheral Nervous System connects CNS to sense receptors, glands, and muscles Autonomic Nervous System governs bodies internal activities Sympathetic Nervous System Somatic Nervous System controls external aspects of the body Parasympathetic Nervous System Electrical Control of Behavior: The Nervous System Sympathetic Nervous System • • Prepares the body for action, especially in response to stress Activates the organs and the glands in the endocrine system Parasympathetic Nervous System • • • Calms the body Slows heart rate and respiration Allows the body to recover from action The Body’s Chemicals Help Control Behavior: The Endocrine System • glands secrete hormones • Endocrine System – glands – cell groups – hormones – chemicals circulating in the body to regulate emotion and behavior The endocrine system interacts with the nervous system. The Body’s Chemicals Help Control Behavior: The Endocrine System • Pituitary Gland – small gland in the center of the brain – the “master gland” – secretes hormones that influence responses to pain – secretes hormones that signal the ovaries and testes to make sex hormones – controls ovulation and the menstrual cycle in women • Adrenal Glands – located on top of the kidneys – produce hormones that regulate body’s salt and water balance – involved in metabolism, the immune system, and sexual development and function – secrete the hormones epinephrine and norepinephrine when we are excited or threatened • Epinephrine and norepinephrine stimulate the sympathetic nervous system The Body’s Chemicals Help Control Behavior: The Endocrine System pancreas secretes hormones to supply body with energy pineal gland secretes melatonin to regulate sleep cycle The Body’s Chemicals Help Control Behavior: The Endocrine System Testes (Male Sex Glands) • Secrete Testosterone – Testosterone regulates body changes related to sexual development. – Testosterone levels are positively associated with aggressive behavior in both men and women. Ovaries (Female Sex Glands) • Secrete Estrogen and Progesterone – Estrogen is involved in the development of female sexual features. – Both hormones are involved in pregnancy and the regulation of the menstrual cycle. The Nervous System and The Endocrine System • Key Takeaways – The body uses both electrical and chemical systems to create homeostasis. – The CNS is made up of bundles of nerves that carry messages to and from the PNS – The Peripheral Nervous System is comprised of the Autonomic Nervous System (ANS) and the Peripheral Nervous System (PNS). The ANS is further divided into the sympathetic (activating) and parasympathetic (calming) nervous systems. These divisions are activated by glands and organs in the endocrine system. – Specific nerves, including sensory neurons, motor neurons, and interneurons, each have specific functions. The Nervous System and The Endocrine System • Key Takeaways, continued – The spinal cord may bypass the brain by responding rapidly using reflexes. – The pituitary gland is a master gland affecting many other glands. – Hormones produced by the pituitary and adrenal glands regulate growth, stress, sexual functions, and chemical balance in the body. – The adrenal glands produce epinephrine and norepinephrine, the hormones responsible for our reactions to stress. – The sex hormones, testosterone, estrogen, and progesterone play an important role in sex differences