First Anatomy and Physiology quiz/test on MONDAY!!! 1- systems and functions 2- science you should already know and why you need to know it Overview of the Systems of the Body _________________: blood circulations with heart and blood vessels _________________: processing food with mouth, stomach and intestines __________________: communicating within the body using hormones ___________________: defending against disease-causing agents ____________________: skin, hair and nails _____________________: structures involved in the transfer of lymph between tissues and the blood stream _______________________: moving the body ___________________: collecting, transferring and processing information with brain and nerves _________________: the sex organs _________________: the organs used for breathing, the lungs _________________________: structural support and protection through bones __________________________: the kidneys and associated structures involved in the production and excretion of urine Science you should already know and why you need to review it. Four macromolecules: * * * * Why are carbs important? Glucose is taken in by cells of the body and broken down to obtain it’s energy Too much glucose gets stored in liver Not enough glucose, liver releases it Diabetics need to regulate carb. Intake Low carbs diet craze – good or bad? Why are proteins important? Main component of muscles (skeletal, cardiac and smooth) Enzymes are proteins (ex lactase) Proteins in nerve cells allow for nervous impulse to transmit Why are lipids important? Main component of all cell membranes Many vitamins are fat soluble Cushioning and protection Too much or too little causes health problems Why are nucleic acids important? DNA is the nucleic acid that dictates all of you traits Genetic disorders are due to problems with DNA sequences RNA helps to build proteins for the body QUIZ time 1 2 3 4 – – – – Carbs Proteins Lipids Nucleic acids Enzymes work by? Lowering activation energy to break down or put together molecules Why Important? – Almost all chemical processes in the body are driven by enzymes. – If enzyme is not working = illness Ex. lactose intolerance ATP is important because? It is the key energy molecule that cells use for driving chemical reactions Glucose is converted into many ATPs ATP does work for all cells – Ex. ATP is needed everytime a muscle contracts or a nerve cell fires We eat and breathe because? We eat and breathe because? We eat mainly to obtain glucose so we can eventually energy for our cells (ATP) We breathe because oxygen is needed to fully break down glucose into ATPs Food and oxygen is required for the process of cellular respiration Chemical equation for eating and breathing Chemical equation for cellular respiration is C6H12O6 + 6O2 6CO2 + 6H2O + energy(ATP) Glucose + Oxygen Carbon Dioxide + Water + ATP Exercising requires Video How do we heal? The need to heal! Mitosis is important because? When cells are damaged or destroyed mitosis is the process that replaces the cells with new ones that are identical to the old ones When an organism grows, mitosis is the process that makes new cells Draw and label a typical animal cell below An ion is? Cation = positively charged ion due to a loss of electrons – Ex. Ca+ needed for a muscle to contract, Na+ and K+ needed for a nerve impulse Anion = negatively charged ion due to gain of electrons – Ex. HCO3 – maintains blood pH An isomer is? Molecules with the same chemical formula and often with the same kinds of bonds between atoms, but in which the atoms are arranged differently. – Ex glucose and fructose are both C6H12O6 but they are different – your cells use glucose directly but must convert fructose to use it Difference between structural and molecular formula is? Structural formula is a graphical picture of how a molecule is arranged Molecular formula is an expression of the types and numbers of atoms in a molecule – Glucose and fructose again as examples Ionic bonds are? An ionic bond is an electrical attraction between two oppositely charged atoms or groups of atoms Na+ and Cl- attract to become NaCl or salt Important because these chemicals disassociate easily in water and can then be used to form ion gradients Covalent bonds are? Bonds formed between elements due to sharing of electrons Very strong bonds Important because – Carbon chains are covalent, cellular structures and macromolecules are carbon based molecules – When a covalent bond is broken – lots of energy is released that can be used by the cells of the body (ex glucose broken down) Polar and non-polar molecules differ because? Polar molecules – “like” water, they dissolve in water (ex salts, water soluble vitamins, ions) Non-polar – “fear” water and don’t dissolve in water (ex, lipids, hydrocarbon chains) Why important? Basis for cells even existing, cell membrane is formed using polar and non-polar molecules MACROMOLECULES 4 Large Molecules Important to Life – Carbohydrates – Lipids – Proteins – Nucleic Acids Stuff to know! Chapter 2-1 Chapter 2-3 •Atomic # •Atomic mass •Atomic structure •Ionic bonds •Covalent bonds •Hydrogen bonds •Water chemistry – Solutions,Solvents,pH – polarity •Carbon chem •Carbohydrates •Lipids •Proteins •Nucleic Acids CARBOHYDRATES (CH2O)n •Functions= provides energy (glucose is energy source for cells Monomers = monosaccharides – Examples = glucose, fructose and galactose (all 3 = C6H12O6 so they are isomer) Two linked = disaccharides – Examples = sucrose (glucose and fructose) and lactose Polymer = polysaccharides – Examples = glycogen (animals) starch (plants) Why “bulk-up” on carbs? Why not eat carbs? CONDENSATION REACTION HOW WOULD THIS GET BROKEN DOWN? H20 HYDROLYSIS PROTEINS Monomers = amino acids All amino acids have – Amine group (NH2) – Carboxyl group (COOH) R-groups differ Dipeptide FUNCTIONS of PROTEINS Structural Hormones Transport Histones ENZYMES!!! Lock and Key Model What symptoms would you have if you had sickle cell anemia? 1 amino acid is wrong in the hemoglobin sequence = mis-shaped RBCs LIPIDS MONOMERS = fatty acids Saturated Unsaturated COMPLEX TRIGLYCERIDES PHOSPHOLIPIDS WAXES FUNCTIONS TRIGLYCERIDES – insulation and energy storage PHOSPHOLIPDS – main component in cell membranes HARDENING OF THE ARTERIES Fats such as cholesterol and saturated fatty acids build up in arteries What other factors contribute to arteriosclerosis? Concept Map Section 2-3 include that consist of that consist of that consist of that consist of which contain which contain which contain which contain Concept Map Section 2-3 Carbon Compounds include Carbohydrates Lipids Nucleic acids that consist of that consist of that consist of that consist of Sugars and starches Fats and oils Nucleotides Amino Acids which contain Carbon, hydrogen, oxygen which contain Carbon, hydrogen, oxygen Proteins which contain which contain Carbon,hydrogen, oxygen, nitrogen, phosphorus Carbon, hydrogen,oxygen, nitrogen, Section Outline Section 2-2 2–2 Properties of Water A.The Water Molecule 1. Polarity 2. Hydrogen Bonds B.Solutions and Suspensions 1. Solutions 2. Suspensions C.Acids, Bases, and pH 1. 2. 3. 4. The pH Scale Acids Bases Buffers Hydrogen bonds Caused by partial positive and negative charges Water is best example ﮦ+ ﮦ- Figure 2-9 NaCI Solution Section 2-2 ClCl- Na+ Na+ Water Water Figure 2-9 NaCI Solution Section 2-2 ClCl- Na+ Na+ Water Water pH Scale Increasingly Basic Section 2-2 Increasingly Acidic Neutral Oven cleaner Bleach Ammonia solution Soap Sea water Human blood Pure water Milk Normal rainfall Acid rain Tomato juice Lemon juice Stomach acid H2O sometimes breaks down into H+ and OH- Interest Grabber continued 1. What are the reactants when wood Section 2-4 Reactants are oxygen and cellulose. burns? 2. What are the products when wood burns? Products are carbon dioxide and water 3. What kinds of energy are given off when wood burns? Light and heat are given off. Some students may also mention sound (the crackling of a fire). 4. Wood doesn’t burn all by itself. What must you do to start a fire? What does this mean in terms of energy? To start a fire, you must light it with a match and kindling. You are giving the wood some energy in the form of heat. 5. Once the fire gets started, it keeps burning. Why don’t you need to keep restarting the fire? Once the fire gets going, it gives off enough heat to start more of the wood burning. Section Outline Section 2-4 2–4 Chemical Reactions and Enzymes A.Chemical Reactions B.Energy in Reactions 1. Energy Changes 2. Activation Energy C.Enzymes D. Enzyme Action 1. The Enzyme-Substrate Complex 2. Regulation of Enzyme Activity Effect of Enzymes Section 2-4 Reaction pathway without enzyme Activation energy without enzyme Reactants Reaction pathway with enzyme Activation energy with enzyme Products Figure 2-19 Chemical Reactions Section 2-4 Energy-Absorbing Reaction Energy-Releasing Reaction Activation energy Products Activation energy Reactants Reactants Products Figure 2-19 Chemical Reactions Section 2-4 Energy-Absorbing Reaction Energy-Releasing Reaction Activation energy Products Activation energy Reactants Reactants Products Enzyme/Substrate Complex Valence electrons are important because? The electrons in the outermost shell of atoms determine type of bonds to be formed Also these electrons have potential energy for our cells to use – When hydrogen loses it’s one valence electron it becomes nothing more than a proton = H+ – Proton “pumps” keep cells working Carbon is especially important to life because? Living organisms are carbon-based life forms. – The molecules that make up our cells (carbs, proteins, lipids and nucleic acids) are ALL made out of carbon chains