The Brain Using lesions helps to understand the working of the brain. What are lesions? Older Brain Structures • Earliest ancestors had a less complex brains system The Brainstem • Oldest, • Begins innermost where the spinal cords swells slightly after entering the skull, medulla Function Controls heartbeat and breathing • Above the medulla, pons Function Helps coordinate movements • Brainstem is the crossover point The Thalamus • Above the brainstem Function: Receives info from the senses, except smell Sends info to higher brain regions that deal with the senses Receives the higher brain replies, sends info to the medulla and cerebellum The Tools of Discovery – Having our Heads Examined • EEG Reads electoral activity in your brain • PET Shows brains use of glucose Like a weather radar, shows the “hot spots” Injects radioactive sugar • MRI Aligns atoms, then disorients them Functional MRI Reveals brains functioning's as well as its structure The Reticular (net-like) Formation • Inside the brainstem, between ears • Neurons which run from the spinal cord up through the thalamus Function Filters incoming stimuli Relays important info to together brain areas Controls arousal What happens if you stimulate it? Cut it? The Cerebellum (little brain) • Rear of brainstem Function Enables nonverbal learning and memory Judges time Modulates our emotions Discriminates sounds and texture Coordinates voluntary movement Alcohols affect Not as coordinated • Injured Hard to wake, keep balance, shake hands Movements jerky or exaggerated • Occurs without conscious effort, brain processes most info outside of our awareness The Limbic System • Between the new and old part of the brain • Made up of the Amygdala Hypothalamus Hippocampus • Function Processes conscious memories • Injury Can’t form new memories • Tied to emotions fear and anger and motives for food and sex The Amygdala • Tied to aggression and fear • Discuss the rhesus monkey and cat The Hypo (just below) thalamus • Bodily maintenance Hunger Body temperature Sexual behavior Maintain a steady internal state (homeostatic) Monitors the state of your body, tunes into your blood chemistry and any incoming orders from together brain parts. Discuss the examples Unfortunately, it is possible for the hypothalamus to lose its ability to communicate with leptin. When this happens, the hypothalamus continuously instructs the cells of the body to increase fat storage by lowering the metabolism, by being hungry and by burning sugar for energy - the exact opposite of what should be happening for the body to function its best and maintain a normal weight. What that means is that for the girl on the left, her hypothalamus is correctly sensing leptin and maintaining her body with normal weight, while for the girl on the right, her hypothalamus is not correctly sensing leptin and therefore, her body cannot lose weight, but continues to store fat, virtually regardless of how little she eats or how much she exercises. The Hypothalamus Cont.d’ • Rewards centers Addictive disorders may be due to reward deficiency syndrome The Cerebral Cortex • Like bark on a tree • Function Perceiving, thinking speaking Control and informational processing center Structure of the Cortex • Unfolded what? • 20 size of – 23 billion what? • 300 trillion what? • Hemispheres’ cortex is subdivided into four lobes separated by fissures (folds) Functions of the Cortex Motor Functions • Right controls left and vice versa. Mapping the Motor Cortex • Brain has no sensory receptors • Body areas requiring precise control like ? and ? occupy the greatest amount of cortical space Discuss experiments with paralyzed patients Sensory Functions • Receives information from the skin senses and movement of body parts • More sensitive the body region, the large the sensory cortex area. Discuss lips and whiskers. • Also have visual cortex in the occipital lobes • Helps identify words, detect emotions, recognize faces • Sound processed in auditory cortex in temporal lobe. Association Areas • Interprets, integrates, acts on sensory information and likes it with stored memories. • Hard to map • In all four lobes • Frontal lobe Judgment, planning, processing new memories Damage Alter personality, no inhibitions, moral judgment unrestrained Discuss Phineas Gage • Parietal lobes Enable mathematical and spatial reasoning • Temporal lobe Recognize faces The Brain’s Plasticity • Ability to modify itself after damage. • May produce new brain cells, neurogenesis • Sever brain and spinal cord neurons usually do not regenerated • Master stem cells found in the human embryo • Some brain areas are reassigned to specific areas • Some neural tissue can reorganize in response to damage • Plasticity may occur, especially with kids Discuss figure 4.17, blindness and deafness • Left hemisphere slow-growing, right may pick up the language Discuss possibilities Our Divided Brain • What is lateralization? • Thought the right side of the brain was minor. • Left side damage impairs reading, writing, speaking, arithmetic reasons, understanding Splitting the Brain • Severed the corpus callosum which carries messages between them • Discuss the experiment by Gazzaniga, and bothersome left-hand independence Right-Left Differences in the Intact Brain • Right hemisphere Perceptual task Self awareness Discuss people with stroke • Speaks or calculates in the left hemisphere • Discuss sedative into the neck artery Fetal Alcohol Syndrome • Brain of baby with no exposure to alcohol • Brain of baby with heavy prenatal exposure to alcohol